ES2059184T3 - Procedimiento para la preparacion de 2,4-diclorofluorobenceno. - Google Patents

Procedimiento para la preparacion de 2,4-diclorofluorobenceno.

Info

Publication number
ES2059184T3
ES2059184T3 ES92117010T ES92117010T ES2059184T3 ES 2059184 T3 ES2059184 T3 ES 2059184T3 ES 92117010 T ES92117010 T ES 92117010T ES 92117010 T ES92117010 T ES 92117010T ES 2059184 T3 ES2059184 T3 ES 2059184T3
Authority
ES
Spain
Prior art keywords
partial
weight
fluorbenzole
mixture
chlorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92117010T
Other languages
English (en)
Inventor
Theodor Dr Papenfuhs
Georg Dr Folz
Ralf Dr Pfirmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2059184T3 publication Critical patent/ES2059184T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/02—Monocyclic aromatic halogenated hydrocarbons
    • C07C25/13—Monocyclic aromatic halogenated hydrocarbons containing fluorine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCESO PARA FABRICACION DEL 2,4 ALTO RENDIMIENTO Y PUREZA SIN SEPARACION INTERMEDIA DE LOS ISOMEROS FORMADOS, EN EL QUE (1) SE NITRURA UNA MOL DE FLUORBENZOL CON UNA MEZCLA, COMPUESTA DE 35 HASTA 65 PARCIAL EN PESO 50 HASTA 90% DE ACIDO SULFURICO Y 35 HASTA 65% PARCIAL EN PESO DE ACIDO SULFONITRICO, COMPUESTO DE 35 HASTA 55 PARCIAL EN PESO 95 HASTA 98% DE ACIDO SULFURICO Y 45 HASTA 65 PARCIAL EN PESO 96 HASTA 98% DE ACIDO NITRICO, CON LA MEDIDA DE QUE SE ALCANCE EL EQUIVALENTE DEL AGENTE NO2+ ANITRURAL DEL 0,8 HASTA 2,0 POR CADA MOL DE FLUORBENZOL PARA SU UTILIZACION, EN UNA TEMPERATURA DE 20 HASTA 90 C PARA EL NITRO FLUORBENZOL, (2) SOBRE MEZCLA DE MATERIA PRIMA DE NITRO FLUORBENZOL QUE CONTIENE 100 G. ACTUA UNA CANTIDAD DE CLORO DE 25 HASTA 150 G. EN PRESENCIA DE UN CATALIZADOR DE CLORACION NUCLEAR EN UNA TEMPERATURA ENTRE 20 Y 100 C, Y (3) SOBRE LA MEZCLA DE MATERIA PRIMA CLORO FLUORNITROBENZOL QUE CONTIENE 100 G. SEGUN LA SEPARACION DEL CATALIZADOR DE CLORACION NUCLEAR ACTUA UNA CANTIDAD EQUIVALENTE DE CLORO APROXIMADA DE 18 G. HASTA 203 G. DE UN MEDIO QUE SUMINISTRA CLORO EN TEMPERATURA DESDE 110 HASTA 220 C Y DE ESTA FORMA A CONTINUACION SE AISLA EL 2,4
ES92117010T 1991-10-11 1992-10-06 Procedimiento para la preparacion de 2,4-diclorofluorobenceno. Expired - Lifetime ES2059184T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4133689 1991-10-11

Publications (1)

Publication Number Publication Date
ES2059184T3 true ES2059184T3 (es) 1994-11-01

Family

ID=6442489

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92117010T Expired - Lifetime ES2059184T3 (es) 1991-10-11 1992-10-06 Procedimiento para la preparacion de 2,4-diclorofluorobenceno.

Country Status (6)

Country Link
US (1) US5227545A (es)
EP (1) EP0539765B1 (es)
JP (1) JP3203067B2 (es)
CA (1) CA2080315A1 (es)
DE (1) DE59200298D1 (es)
ES (1) ES2059184T3 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010058421A2 (en) * 2008-11-18 2010-05-27 Aditya Birla Science & Technology Co. Ltd. A process for synthesis of 2, 4-dichloro-5- fluoroacetophenone (dcfa)
CN102617360B (zh) * 2012-03-01 2013-11-06 江西吉翔医药化工有限公司 3,5-二氯-2,4-二氟苯胺的合成方法
CN104974009A (zh) * 2015-06-05 2015-10-14 朱卫 二氯氟苯的合成方法
CN106631811A (zh) * 2016-11-23 2017-05-10 山东友帮生化科技有限公司 一种3‑氯‑4‑氟硝基苯的制备方法
CN113582805A (zh) * 2020-04-30 2021-11-02 浙江省常山长盛化工有限公司 一种以邻二氯苯为原料生产高纯度2,4-二氯氟苯的生产工艺
CN113248353B (zh) * 2021-07-01 2022-02-25 山东国邦药业有限公司 一种2,4-二氯-5-氟苯乙酮的制备方法
CN113248354B (zh) * 2021-07-07 2022-04-22 山东国邦药业有限公司 一种氟氯苯乙酮的合成方法
CN113429254A (zh) * 2021-07-22 2021-09-24 浙江解氏新材料股份有限公司 一种基于陶瓷填料塔的2，4-二氯氟苯的高效合成方法
CN115650855B (zh) * 2022-11-03 2024-08-02 山东东岳高分子材料有限公司 用微反应器制备对氟硝基苯和2，4-二硝基氟苯的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130521C (es) * 1962-12-19
EP0307481B1 (en) * 1987-03-25 1993-11-24 Nippon Kayaku Kabushiki Kaisha Process for preparing 3-chloro-4-fluoronitrobenzene
DE68919584T2 (de) * 1988-08-26 1995-06-01 Asahi Glass Co Ltd Verfahren zur Herstellung von Chlorfluorbenzolen.
US5157169A (en) * 1992-03-26 1992-10-20 Mallinckrodt Specialty Chemicals Company Preparation of 3-halo-halobenzenes and 1-halo-3,5-dihalobenzenes

Also Published As

Publication number Publication date
EP0539765A1 (de) 1993-05-05
JP3203067B2 (ja) 2001-08-27
EP0539765B1 (de) 1994-07-20
CA2080315A1 (en) 1993-04-12
DE59200298D1 (de) 1994-08-25
JPH05301833A (ja) 1993-11-16
US5227545A (en) 1993-07-13

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