ES2059546T3 - Empleo de un inhibidor de catecol-o-metil-transferasa (comt) una de sus sales o esteres fisiologicamente aceptables. - Google Patents

Empleo de un inhibidor de catecol-o-metil-transferasa (comt) una de sus sales o esteres fisiologicamente aceptables.

Info

Publication number
ES2059546T3
ES2059546T3 ES88312228T ES88312228T ES2059546T3 ES 2059546 T3 ES2059546 T3 ES 2059546T3 ES 88312228 T ES88312228 T ES 88312228T ES 88312228 T ES88312228 T ES 88312228T ES 2059546 T3 ES2059546 T3 ES 2059546T3
Authority
ES
Spain
Prior art keywords
catecol
comt
transferase
inhibitor
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88312228T
Other languages
English (en)
Inventor
Paivi Aho
Pentti Pohto
Inge-Britt Linden
Reijo Backstrom
Erkki Honkanen
Erkki Nissinen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Yhtyma Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878730190A external-priority patent/GB8730190D0/en
Application filed by Orion Yhtyma Oy filed Critical Orion Yhtyma Oy
Application granted granted Critical
Publication of ES2059546T3 publication Critical patent/ES2059546T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A61K31/06—Phenols the aromatic ring being substituted by nitro groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

DERIVADOS DE CATECOL QUE HAN SIDO PREVIAMENTE SUGERIDOS SON UTILES EN EL TRATAMIENTO Y PROFILAXIS DE ULCERAS Y LESIONES EN EL TACTO GASTROINTESTINAL.
ES88312228T 1987-12-24 1988-12-22 Empleo de un inhibidor de catecol-o-metil-transferasa (comt) una de sus sales o esteres fisiologicamente aceptables. Expired - Lifetime ES2059546T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878730190A GB8730190D0 (en) 1987-12-24 1987-12-24 New use of catechol-o-methyl transferase(comt)inhibitors & their physiologically acceptable salts & esters
GB888820729A GB8820729D0 (en) 1987-12-24 1988-09-01 Substituted beta-diketones

Publications (1)

Publication Number Publication Date
ES2059546T3 true ES2059546T3 (es) 1994-11-16

Family

ID=26293247

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88312228T Expired - Lifetime ES2059546T3 (es) 1987-12-24 1988-12-22 Empleo de un inhibidor de catecol-o-metil-transferasa (comt) una de sus sales o esteres fisiologicamente aceptables.

Country Status (17)

Country Link
US (1) US5001152A (es)
EP (1) EP0323162B1 (es)
JP (1) JPH02196715A (es)
AU (1) AU617397B2 (es)
BE (1) BE1003759A5 (es)
CH (1) CH683395A5 (es)
DE (1) DE3843324A1 (es)
DK (1) DK713288A (es)
ES (1) ES2059546T3 (es)
HU (1) HU200684B (es)
IE (1) IE883816L (es)
IL (1) IL88734A (es)
IT (1) IT1227914B (es)
LU (1) LU87412A1 (es)
MT (1) MTP1031B (es)
PH (1) PH27037A (es)
SE (1) SE8804608L (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
GB9004348D0 (en) * 1990-02-27 1990-04-25 Orion Yhtymae Oy New use of catechol derivatives and their physiologically acceptable salts and esters
GB9002337D0 (en) * 1990-02-02 1990-04-04 Orion Yhtymae Oy Compounds useful in treating inflammatory bowel disease
US5185370A (en) * 1988-09-01 1993-02-09 Orion-Yhtyma Oy Substituted β-diketones and their use
IL91382A (en) * 1988-09-01 1995-06-29 Orion Yhtymae Oy Alkenyl or arylmethylene-substituted beta-diketones their preparation and pharmaceutical compositions containing them
JPH05301838A (ja) * 1991-10-15 1993-11-16 Mitsubishi Kasei Corp スチレン誘導体
GB9626472D0 (en) * 1996-12-20 1997-02-05 Aperia Anita C New use of comt inhibitors
FI981521A0 (fi) 1998-07-01 1998-07-01 Orion Corp Substituoidut beta-diketonit ja niiden käyttö
FI20000635A0 (fi) * 2000-03-17 2000-03-17 Orion Yhtymae Oyj COMT-inhibiittoreiden käyttö analgeettina
GB0015228D0 (en) * 2000-06-21 2000-08-16 Portela & Ca Sa Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB902586A (en) * 1960-01-01 1962-08-01 Shell Res Ltd Herbicidal compositions and novel compounds for use therein
GB1188364A (en) * 1967-05-02 1970-04-15 May & Baker Ltd Quinoline Derivatives
BE759266A (fr) * 1969-11-24 1971-05-24 Hoffmann La Roche Procede pour la preparation de derives de l'indole
CA1190223A (en) * 1977-11-01 1985-07-09 National Research Development Corporation Substrates for enzymes
FR2504004A1 (fr) * 1981-04-17 1982-10-22 Roussel Uclaf Application a titre de medicaments de derives d'acides phenyl aliphatique carboxyliques
JPS5890534A (ja) * 1981-11-25 1983-05-30 Ono Pharmaceut Co Ltd ２−アミノフエノ−ル誘導体、その製造方法およびその誘導体を有効成分として含有する治療剤
ES8505914A1 (es) * 1983-05-13 1985-06-16 Yamanouchi Pharma Co Ltd Un procedimiento para la produccion de un derivado de catecol
FR2557097B1 (fr) * 1983-12-22 1986-06-13 Rhone Poulenc Spec Chim Procede de preparation de bromobenzaldehydes hydroxy et/ou alkoxy substitues
FR2557098B1 (fr) * 1983-12-22 1986-06-13 Rhone Poulenc Spec Chim Procede de preparation de bromobenzaldehydes hydroxy et/ou alkoxy substitues
US4760089A (en) * 1985-09-09 1988-07-26 Smithkline Beckman Corporation Irreversible dopamine-β-hydroxylase inhibitors
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
DK49688A (da) * 1987-03-20 1988-09-21 Hoffmann La Roche Propiolophenonderivater

Also Published As

Publication number Publication date
BE1003759A5 (fr) 1992-06-09
LU87412A1 (fr) 1989-06-14
IL88734A0 (en) 1989-07-31
IE883816L (en) 1989-06-24
EP0323162B1 (en) 1993-09-15
EP0323162A2 (en) 1989-07-05
HU200684B (en) 1990-08-28
AU2745988A (en) 1989-06-29
IT1227914B (it) 1991-05-14
DE3843324A1 (de) 1989-07-06
CH683395A5 (de) 1994-03-15
DK713288D0 (da) 1988-12-21
AU617397B2 (en) 1991-11-28
EP0323162A3 (en) 1990-11-14
MTP1031B (en) 1990-10-04
SE8804608L (sv) 1989-06-25
SE8804608D0 (sv) 1988-12-21
IL88734A (en) 1994-01-25
PH27037A (en) 1993-02-01
HUT49053A (en) 1989-08-28
IT8823107A0 (it) 1988-12-23
US5001152A (en) 1991-03-19
JPH02196715A (ja) 1990-08-03
DK713288A (da) 1989-06-25

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