ES2059691T3 - Gen y estructura de gen que codifica una aminotransferasa y microorganismos que expresan este gen. - Google Patents

Gen y estructura de gen que codifica una aminotransferasa y microorganismos que expresan este gen.

Info

Publication number
ES2059691T3
ES2059691T3 ES89122939T ES89122939T ES2059691T3 ES 2059691 T3 ES2059691 T3 ES 2059691T3 ES 89122939 T ES89122939 T ES 89122939T ES 89122939 T ES89122939 T ES 89122939T ES 2059691 T3 ES2059691 T3 ES 2059691T3
Authority
ES
Spain
Prior art keywords
gen
aminotransferase
microorganisms
express
codes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89122939T
Other languages
English (en)
Inventor
Klaus Dr Bartsch
Arno Dr Schulz
Eugen Dr Uhlmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3842174A external-priority patent/DE3842174A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2059691T3 publication Critical patent/ES2059691T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA PRODUCCION DEL ACIDO L-2-AMINO-4-METUILFOSFINOBUTIRICO (L-PPT) A TRAVES DE LA TRANSAMINACION DEL ACIDO (3-CARBOXI-3-OXOPROPIL)-METILFOSFONICO CON AYUDA DE LA TRANSAMINASA ESPECIFICA (L-PPT) DE E COLI -DH-1 ES MUY EFECTIVA CUANDO SE AISLA EL GEN CODIFICADOR PARA LA ENZIMA, SE INSTALA EN UN PLASMIDO Y SE TRANSFORMA POR UN MICROORGANISMO.
ES89122939T 1988-12-15 1989-12-12 Gen y estructura de gen que codifica una aminotransferasa y microorganismos que expresan este gen. Expired - Lifetime ES2059691T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3842174A DE3842174A1 (de) 1988-12-15 1988-12-15 Gen und genstruktur, codierend fuer eine aminotransferase, und mikroorganismen, die dieses gen exprimieren
DE3932015A DE3932015A1 (de) 1988-12-15 1989-09-26 Gen und genstruktur, codierend fuer eine aminotransferase, mikroorganismen, die dieses gen exprimieren, und transaminierungsverfahren unter verwendung des expressionsprodukts

Publications (1)

Publication Number Publication Date
ES2059691T3 true ES2059691T3 (es) 1994-11-16

Family

ID=25875159

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89122939T Expired - Lifetime ES2059691T3 (es) 1988-12-15 1989-12-12 Gen y estructura de gen que codifica una aminotransferasa y microorganismos que expresan este gen.

Country Status (10)

Country Link
US (4) US5221737A (es)
EP (1) EP0373597B1 (es)
JP (1) JP2986492B2 (es)
KR (1) KR0159764B1 (es)
AU (1) AU626357B2 (es)
DE (2) DE3932015A1 (es)
DK (1) DK634289A (es)
ES (1) ES2059691T3 (es)
IL (1) IL92688A (es)
NZ (1) NZ231748A (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3818851A1 (de) * 1988-06-03 1989-12-14 Hoechst Ag Neue transaminase, ihre herstellung und ihre verwendung
DE3932015A1 (de) * 1988-12-15 1991-04-04 Hoechst Ag Gen und genstruktur, codierend fuer eine aminotransferase, mikroorganismen, die dieses gen exprimieren, und transaminierungsverfahren unter verwendung des expressionsprodukts
US6455287B1 (en) 1995-02-23 2002-09-24 Wyeth Mechanical disruption of bacterial cells for plasmid recovery
DE19919848A1 (de) 1999-04-30 2000-11-02 Aventis Cropscience Gmbh Verfahren zur Herstellung von L-Phosphinothricin durch enzymatische Transaminierung mit Aspartat
US8498207B2 (en) * 2008-06-26 2013-07-30 Reverb Networks Dynamic load balancing
US20110090820A1 (en) 2009-10-16 2011-04-21 Osama Hussein Self-optimizing wireless network
US9826416B2 (en) * 2009-10-16 2017-11-21 Viavi Solutions, Inc. Self-optimizing wireless network
US8385900B2 (en) * 2009-12-09 2013-02-26 Reverb Networks Self-optimizing networks for fixed wireless access
US8509762B2 (en) 2011-05-20 2013-08-13 ReVerb Networks, Inc. Methods and apparatus for underperforming cell detection and recovery in a wireless network
EP2754271B1 (en) 2011-09-09 2019-11-13 Reverb Networks Inc. Methods and apparatus for implementing a self optimizing-organizing network manager
US9258719B2 (en) 2011-11-08 2016-02-09 Viavi Solutions Inc. Methods and apparatus for partitioning wireless network cells into time-based clusters
WO2013069645A1 (ja) * 2011-11-10 2013-05-16 ヒューマン・メタボローム・テクノロジーズ株式会社 エタノールアミンリン酸の測定方法
US9008722B2 (en) 2012-02-17 2015-04-14 ReVerb Networks, Inc. Methods and apparatus for coordination in multi-mode networks
US9113353B1 (en) 2015-02-27 2015-08-18 ReVerb Networks, Inc. Methods and apparatus for improving coverage and capacity in a wireless network
CN116121315A (zh) 2016-03-02 2023-05-16 巴斯夫欧洲公司 制造l-草胺膦的方法
CN107119084B (zh) * 2017-03-23 2019-12-17 浙江大学 一种利用转氨酶和乙烯合成酶生产l-草铵膦的方法
CN107630052B (zh) * 2017-03-29 2018-05-29 武汉茵茂特生物技术有限公司 L-草铵膦的生物转化方法
CN110343676B (zh) 2018-04-03 2020-06-23 上海弈柯莱生物医药科技有限公司 一种l-谷氨酸脱氢酶突变体及其应用
CN111019916B (zh) 2018-11-23 2020-12-08 弈柯莱生物科技(上海)股份有限公司 一种d-氨基酸氧化酶突变体及其应用
CN111979208B (zh) 2019-05-23 2023-01-10 弈柯莱生物科技(上海)股份有限公司 一种l-谷氨酸脱氢酶突变体及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6178378A (ja) * 1984-09-27 1986-04-21 Ajinomoto Co Inc 芳香族アミノ酸生合成遺伝子を含有する組換えｄｎａ及びそれを有するコリネ型細菌
EP0183175B1 (en) * 1984-11-20 1990-03-14 Ajinomoto Co., Inc. Coryneform bacteria carrying recombinant dna and a process for producing aromatic amino acids using said bacteria
DE3786707D1 (de) * 1986-06-04 1993-09-02 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin durch transaminierung.
US4968629A (en) * 1986-08-20 1990-11-06 Hematology Marketing Associates, Inc. Blood diluent for automatic and semi-automatic determination of white cells and method of utilizing same
DE3636722A1 (de) * 1986-10-29 1988-05-05 Hoechst Ag Klonierung und verwendung des transaminase-gens ilve
DE3818851A1 (de) * 1988-06-03 1989-12-14 Hoechst Ag Neue transaminase, ihre herstellung und ihre verwendung
EP0349965A3 (en) * 1988-07-04 1990-06-13 Meiji Seika Kaisha Ltd. Novel genes encoding transaminase
DE3932015A1 (de) * 1988-12-15 1991-04-04 Hoechst Ag Gen und genstruktur, codierend fuer eine aminotransferase, mikroorganismen, die dieses gen exprimieren, und transaminierungsverfahren unter verwendung des expressionsprodukts

Also Published As

Publication number Publication date
DE3932015A1 (de) 1991-04-04
EP0373597A3 (de) 1991-08-28
US5888782A (en) 1999-03-30
KR900009981A (ko) 1990-07-06
DE58905773D1 (de) 1993-11-04
JP2986492B2 (ja) 1999-12-06
DK634289A (da) 1990-06-16
AU4614689A (en) 1990-06-21
EP0373597A2 (de) 1990-06-20
KR0159764B1 (ko) 1998-11-16
IL92688A0 (en) 1990-09-17
NZ231748A (en) 1991-10-25
JPH02207789A (ja) 1990-08-17
DK634289D0 (da) 1989-12-14
US5221737A (en) 1993-06-22
US6051408A (en) 2000-04-18
US6210934B1 (en) 2001-04-03
EP0373597B1 (de) 1993-09-29
AU626357B2 (en) 1992-07-30
IL92688A (en) 1996-10-31

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