ES2060563T3 - Principios activos pulverulentos estabilizados, composiciones contenidas, su proceso de obtencion y sus aplicaciones. - Google Patents

Principios activos pulverulentos estabilizados, composiciones contenidas, su proceso de obtencion y sus aplicaciones.

Info

Publication number
ES2060563T3
ES2060563T3 ES93402877T ES93402877T ES2060563T3 ES 2060563 T3 ES2060563 T3 ES 2060563T3 ES 93402877 T ES93402877 T ES 93402877T ES 93402877 T ES93402877 T ES 93402877T ES 2060563 T3 ES2060563 T3 ES 2060563T3
Authority
ES
Spain
Prior art keywords
cellulose
stabilised
active agents
agent
vinylpyrrolidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93402877T
Other languages
English (en)
Other versions
ES2060563T1 (es
Inventor
Guy Derrieu
Bernard Raynier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Virbac SA
Original Assignee
Laboratoires Virbac SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9436026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2060563(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratoires Virbac SA filed Critical Laboratoires Virbac SA
Publication of ES2060563T1 publication Critical patent/ES2060563T1/es
Application granted granted Critical
Publication of ES2060563T3 publication Critical patent/ES2060563T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/74—Fixation, conservation, or encapsulation of flavouring agents with a synthetic polymer matrix or excipient, e.g. vinylic, acrylic polymers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A61K8/8182—Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/624—Coated by macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Detergent Compositions (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Glanulating (AREA)
  • Grain Derivatives (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Seeds, Soups, And Other Foods (AREA)

Abstract

PRINCIPIOS ACTIVOS PULVERULENTOS ESTABILIZADOS, COMPOSICIONES QUE LOS CONTIENEN ASI COMO PROCESO DE OBTENCION DE TALES PRINCIPIOS ACTIVOS ESTABILIZADOS QUE PERMITEN OBTENER COMPOSICIONES FARMACEUTICAS, DIETETICAS, ALIMENTARIAS O COSMETICAS, SECAS Y ESTABLES, EN LAS CUALES LAS PROPIEDADES DE DICHOS PRINCIPIOS ACTIVOS NO ESTAN NI MODIFICADAS NI ALTERADAS. TALES PRINCIPIOS ACTIVOS PULVERULENTOS ESTAN ESTABILIZADOS POR REVESTIMIENTO CON UNA COMPOSICION DE REVESTIMIENTO QUE COMPRENDE: ENOS UN AGENTE FILMOGENO, EN PROPORCIONES COMPRENDIDAS ENTRE 2 Y 25% EN PESO DE LA MASA FINAL, SELECCIONADO ENTRE POLIVINIL PIRROLIDONAS (POVIDONA), ALCOHOLES POLIVINILICOS, COPOLIMERO VINILPIRROLIDONA-ACETATO DE VINILO, COPOLIMERO VINILPIRROLIDONA-ALCOHOL POLIVINILICO, DERIVADOS CELULOSICOS TALES COMO ACETATO DE CELULOSA, ACETATO DE CELULOSA FTALATO, BUTIRATO DE CELULOSA, ETILCELULOSA, METILCELULOSA, POLIMEROS Y COPOLIMEROS ACRILICOS Y METACRILICOS Y CERAS VEGETALES, ANIMALES O SINTETICAS, Y AL MENOS UN AGENTE POROGENO, EN PROPORCIONES COMPRENDIDAS ENTRE 0 Y 5% PREFERENTEMENTE ENTRE 0,5 Y 5% EN PESO DE LA MASA FINAL, SELECCIONADO ENTRE LA LACTOSA MICROCRISTALINA, POLIETILENOS GLICOLES DE BAJO PESO MOLECULAR, EL CARBONATO DE CALCIO, FOSFATO DE CALCIO, SACAROSA, CLORURO DE SODIO Y CLORURO DE POTASIO. EL PRODUCTO ACTIVO PULVERULENTO ESTABILIZADO, BAJO LA FORMA DE MICROPARTICULAS, PRESENTA UNA GRANULOMETRIA COMPRENDIDA ENTRE 50 Y 1000 (MU)M, PREFERENTEMENTE ENTRE 200 Y 500 (MU)M.
ES93402877T 1992-11-30 1993-11-29 Principios activos pulverulentos estabilizados, composiciones contenidas, su proceso de obtencion y sus aplicaciones. Expired - Lifetime ES2060563T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214365A FR2698560B1 (fr) 1992-11-30 1992-11-30 Principes actifs pulvérulents stabilisés, compositions les contenant, leur procédé d'obtention et leurs applications.

Publications (2)

Publication Number Publication Date
ES2060563T1 ES2060563T1 (es) 1994-12-01
ES2060563T3 true ES2060563T3 (es) 1997-09-16

Family

ID=9436026

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93402877T Expired - Lifetime ES2060563T3 (es) 1992-11-30 1993-11-29 Principios activos pulverulentos estabilizados, composiciones contenidas, su proceso de obtencion y sus aplicaciones.

Country Status (13)

Country Link
US (1) US5595762A (es)
EP (1) EP0600775B1 (es)
JP (1) JPH06292825A (es)
AT (1) ATE152617T1 (es)
AU (1) AU667588B2 (es)
CA (1) CA2110370C (es)
DE (2) DE600775T1 (es)
DK (1) DK0600775T3 (es)
ES (1) ES2060563T3 (es)
FR (1) FR2698560B1 (es)
GR (2) GR940300063T1 (es)
NZ (1) NZ250331A (es)
ZA (1) ZA938938B (es)

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CA2110370A1 (en) 1994-05-31
JPH06292825A (ja) 1994-10-21
NZ250331A (en) 1997-05-26
EP0600775B1 (fr) 1997-05-07
GR940300063T1 (en) 1994-09-30
ZA938938B (en) 1994-09-28
GR3024231T3 (en) 1997-10-31
FR2698560A1 (fr) 1994-06-03
DE69310484D1 (de) 1997-06-12
US5595762A (en) 1997-01-21
FR2698560B1 (fr) 1995-02-03
AU5197193A (en) 1994-06-09
AU667588B2 (en) 1996-03-28
CA2110370C (en) 2009-09-22
DE69310484T2 (de) 1997-12-11
ES2060563T1 (es) 1994-12-01
ATE152617T1 (de) 1997-05-15
DK0600775T3 (da) 1997-10-13
DE600775T1 (de) 1995-04-06
EP0600775A1 (fr) 1994-06-08

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