ES2060676T3 - Metodo, reactivo, estuche y anticuerpo monoclonal para diagnosticar cancer en organos digestivos humanos por determinacion de glutation-s-transferasa humana. - Google Patents

Metodo, reactivo, estuche y anticuerpo monoclonal para diagnosticar cancer en organos digestivos humanos por determinacion de glutation-s-transferasa humana.

Info

Publication number
ES2060676T3
ES2060676T3 ES89101717T ES89101717T ES2060676T3 ES 2060676 T3 ES2060676 T3 ES 2060676T3 ES 89101717 T ES89101717 T ES 89101717T ES 89101717 T ES89101717 T ES 89101717T ES 2060676 T3 ES2060676 T3 ES 2060676T3
Authority
ES
Spain
Prior art keywords
human
glutation
reagent
transferase
monoclonal antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89101717T
Other languages
English (en)
Inventor
Kenji Hosoda
Hitomi Honda
Takaharu Kubota
Hideaki Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP63268292A external-priority patent/JPH0750115B2/ja
Priority claimed from JP63282546A external-priority patent/JPH02131595A/ja
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of ES2060676T3 publication Critical patent/ES2060676T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

UN METODO PARA DETERMINAR INMUNOLOGICAMENTE GLUTATIONA S-TRANSFERASA ACIDA HUMANA EN UNA MUESTRA DE ENSAYO HUMANA, QUE CONSISTE EN PONER LA MUESTRA DE ENSAYO EN CONTACTO CON UN PRIMER ANTICUERPO LIGADO A UN SOPORTE INSOLUBLE Y UN SEGUNDO ANTICUERPO MARCADO, SIENDO EL PRIMER O SEGUNDO ANTICUERPOS UN ANTICUERPO POLICLONAL CAPAZ DE RECONOCER GLUTATIONA S-TRANSFERASA ACIDA HUMANA O UN FRAGMENTO EQUIVALENTE DEL ANTICUERPO POLICLONAL, Y SIENDO EL OTRO ANTICUERPO UNO MONOCLONAL CAPAZ DE RECONOCER ESPECIFICAMENTE GLUTATIONA S-TRANSFERASA ACIDA HUMANA O UN FRAGMENTO EQUIVALENTE DEL ANTICUERPO MONOCLONAL, UN METODO PARA DIAGNOSTICAR CANCER EN UN ORGANO DIGESTIVO HUMANO UTILIZANDO EL METODO ANTERIOR, UN REACTIVO PARA ESTE, UN CONJUNTO PARA ELLO Y UN ANTICUERPO MONOCLONAL PARA USAR EL EL.
ES89101717T 1988-02-01 1989-02-01 Metodo, reactivo, estuche y anticuerpo monoclonal para diagnosticar cancer en organos digestivos humanos por determinacion de glutation-s-transferasa humana. Expired - Lifetime ES2060676T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1960288 1988-02-01
JP63268292A JPH0750115B2 (ja) 1988-02-01 1988-10-26 ヒト酸性グルタチオンｓ―トランスフェラーゼの測定方法
JP63282546A JPH02131595A (ja) 1988-11-10 1988-11-10 ヒトの胎盤由来グルタチオンｓ−トランスフェラーゼに対するモノクローナル抗体

Publications (1)

Publication Number Publication Date
ES2060676T3 true ES2060676T3 (es) 1994-12-01

Family

ID=27282694

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89101717T Expired - Lifetime ES2060676T3 (es) 1988-02-01 1989-02-01 Metodo, reactivo, estuche y anticuerpo monoclonal para diagnosticar cancer en organos digestivos humanos por determinacion de glutation-s-transferasa humana.

Country Status (4)

Country Link
EP (1) EP0328939B1 (es)
AU (1) AU608117B2 (es)
DE (1) DE68911550T2 (es)
ES (1) ES2060676T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051356A (en) * 1988-06-13 1991-09-24 Eastman Kodak Company Specific binding composition comprising a low pI protein or carbohydrate and a diagnostic test kit and method of use
US5217868A (en) * 1992-05-01 1993-06-08 Syncor Limited Measurement of an enzyme marker as an aid to diagnosis of liver transplant rejection
EP0692716A1 (en) * 1994-07-12 1996-01-17 Bayer Ag Method of assaying for glutathione- S-transferase and diagnostic test therefrom
AU2002220668A1 (en) * 2000-10-31 2002-05-15 Bayer Aktiengesellschaft Regulation of human glutathione-s-transferase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3686766T2 (de) * 1985-11-21 1993-04-22 Teijin Ltd Monoklonaler antikoerper gegen glutathion s-transferase und dessen verwendung zur diagnose von krebs.

Also Published As

Publication number Publication date
AU608117B2 (en) 1991-03-21
EP0328939A3 (en) 1990-05-30
DE68911550T2 (de) 1994-05-11
DE68911550D1 (de) 1994-02-03
EP0328939B1 (en) 1993-12-22
AU2952489A (en) 1989-08-03
EP0328939A2 (en) 1989-08-23

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