ES2061236T3 - Derivados de la urea, su preparacion y los medicamentos que les contienen. - Google Patents

Derivados de la urea, su preparacion y los medicamentos que les contienen.

Info

Publication number
ES2061236T3
ES2061236T3 ES91906784T ES91906784T ES2061236T3 ES 2061236 T3 ES2061236 T3 ES 2061236T3 ES 91906784 T ES91906784 T ES 91906784T ES 91906784 T ES91906784 T ES 91906784T ES 2061236 T3 ES2061236 T3 ES 2061236T3
Authority
ES
Spain
Prior art keywords
pct
preparation
radical
medicines
urea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91906784T
Other languages
English (en)
Inventor
Jean-Dominique Bourzat
Marc Capet
Claude Cotrel
Claude Guyon
Franco Manfre
Gerard Roussel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of ES2061236T3 publication Critical patent/ES2061236T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

COMPUESTOS DE FORMULA (I) EN LA QUE R1 REPRESENTA UN RADICAL ALKILO, R2 REPRESENTA UN RADICAL FENILO O UNA CADENA -CH2)M-COR4 EN LA QUE M ES IGUAL A 0, 1 O 2 Y R4 REPRESENTA UN RADICAL HIDROXI, ALCOXI O AMINO, R3 REPRESENTA UN ATOMO DE HIDROGENO O UN RADICAL ALKILO, ALCOXI O ALKILTIO, N ES IGUAL A 0 O 1, SU PREPARACION Y LOS MEDICAMENTOS QUE LOS CONTIENEN.
ES91906784T 1990-03-13 1991-03-11 Derivados de la urea, su preparacion y los medicamentos que les contienen. Expired - Lifetime ES2061236T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9003187A FR2659653B1 (fr) 1990-03-13 1990-03-13 Derives de l'uree, leur preparation et les medicaments les contenant.

Publications (1)

Publication Number Publication Date
ES2061236T3 true ES2061236T3 (es) 1994-12-01

Family

ID=9394668

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91906784T Expired - Lifetime ES2061236T3 (es) 1990-03-13 1991-03-11 Derivados de la urea, su preparacion y los medicamentos que les contienen.

Country Status (16)

Country Link
US (1) US5338760A (es)
EP (1) EP0520016B1 (es)
JP (1) JPH05504970A (es)
AT (1) ATE112552T1 (es)
AU (1) AU637220B2 (es)
CA (1) CA2074365A1 (es)
DE (1) DE69104475T2 (es)
ES (1) ES2061236T3 (es)
FR (1) FR2659653B1 (es)
HU (1) HUT61574A (es)
IE (1) IE910821A1 (es)
IL (1) IL97511A0 (es)
NZ (1) NZ237379A (es)
PT (1) PT97027A (es)
WO (1) WO1991013862A1 (es)
ZA (1) ZA911767B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667864B2 (fr) * 1990-03-07 1994-08-05 Rhone Poulenc Sante Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant.
US5389682A (en) * 1992-09-18 1995-02-14 Warner-Lambert Company Agents acting at cholecystokinin receptors
FR2700168B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
FR2700167B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine et thiazolidine, leur préparation et les médicaments les contenant.
CZ267695A3 (en) * 1993-04-15 1996-04-17 Glaxo Wellcome Inc 1,5-benzodiazepine derivatives, process of their preparation, their use and pharmaceutical preparations containing thereof
GB9307833D0 (en) * 1993-04-15 1993-06-02 Glaxo Inc Modulators of cholecystokinin and gastrin
PT739903E (pt) * 1994-02-09 2002-05-31 Shionogi & Co Derivado carbamoilmetilureia
ES2164258T3 (es) * 1995-08-07 2002-02-16 Shionogi & Co Procedimiento de preparacion de derivados de carbamoilmetilurea.
US6972296B2 (en) 1999-05-07 2005-12-06 Encysive Pharmaceuticals Inc. Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
SI21096B (sl) * 2001-10-09 2012-05-31 Encysive Pharmaceuticals Inc Derivati karboksilne kisline ki inhibirajo vezavo integrinov na njihove receptorje
DE602005004765T2 (de) * 2004-03-16 2009-02-12 Nippon Shokubai Co. Ltd. Additiv für hydraulisches material

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2646847B1 (fr) * 1989-05-12 1991-07-12 Rhone Poulenc Sante N-phenyl amides, leurs procedes de preparation et les medicaments les contenant

Also Published As

Publication number Publication date
IL97511A0 (en) 1992-06-21
HUT61574A (en) 1993-01-28
ATE112552T1 (de) 1994-10-15
WO1991013862A1 (fr) 1991-09-19
FR2659653A1 (fr) 1991-09-20
HU9202919D0 (en) 1992-12-28
ZA911767B (en) 1991-12-24
PT97027A (pt) 1991-11-29
US5338760A (en) 1994-08-16
AU7570491A (en) 1991-10-10
JPH05504970A (ja) 1993-07-29
IE910821A1 (en) 1991-09-25
NZ237379A (en) 1992-11-25
EP0520016A1 (fr) 1992-12-30
CA2074365A1 (fr) 1991-09-14
AU637220B2 (en) 1993-05-20
FR2659653B1 (fr) 1992-05-22
DE69104475D1 (de) 1994-11-10
DE69104475T2 (de) 1995-02-23
EP0520016B1 (fr) 1994-10-05

Similar Documents

Publication Publication Date Title
FI880494A0 (fi) Nya 5-alkoxi-2,4 -diaminoalkylbenzener samt dessa innehaollande haorfaergningsmedel.
TW274547B (es)
NZ237052A (en) N-phenyl-n-acetamidoglycinamide derivatives and pharmaceutical compositions
IL97476A0 (en) N-phenylglycinamide derivatives,their preparation,pharmaceutical compositions containing them and their application
FI894061A0 (fi) Menetelmä lääkeaineina käyttökelpoisten , -disubstituoitujen N-sykloalkyylialkyylibentsyyliamiinien valmistamiseksi ja niiden synteesivälituotteita
DE59509537D1 (de) Pyrimidin- oder triazincarbonsäurederivate zur verwendung als arzneimittel
DE69104475D1 (de) Harnstoffderivate, ihre herstellung und deren enthaltende arzneimittel.
ES2057802T3 (es) Nuevos derivados de 3-amino-cromano, procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DK0465369T3 (da) N-substituerede derivater af alpha-mercaptoalkylaminer, deres fremstilling og anvendelse som lægemidler, farmaceutiske præparater med indhold deraf samt mellemprodukter
ES2105145T3 (es) Nuevos derivados de la pirrolidina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
SE8303913L (sv) Heterocykliska foreningar
ES2057901T3 (es) Derivados de benzotiazol, su preparacion y los medicamentos que les contienen.
ES2062772T3 (es) N-fenil n-alcoxicarbonilalquilo glicinamidas, su preparacion y los medicamentos que les contienen.
ES2140393T3 (es) Compuestos de penem.
ZA894399B (en) New derivatives of phenothiazine,their preparation and the compositions which contain them
FI943644A0 (fi) Uudet happoanhydridit, niiden valmistus ja käyttö

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 520016

Country of ref document: ES