ES2061544T3 - Nuevos derivados de glucopiranosa. - Google Patents
Nuevos derivados de glucopiranosa.Info
- Publication number
- ES2061544T3 ES2061544T3 ES88106313T ES88106313T ES2061544T3 ES 2061544 T3 ES2061544 T3 ES 2061544T3 ES 88106313 T ES88106313 T ES 88106313T ES 88106313 T ES88106313 T ES 88106313T ES 2061544 T3 ES2061544 T3 ES 2061544T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- chem
- general formula
- integer
- similar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical class OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 5
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 230000001939 inductive effect Effects 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 230000002708 enhancing effect Effects 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 2
- -1 sulfoxymethyl group Chemical group 0.000 abstract 2
- 102000000589 Interleukin-1 Human genes 0.000 abstract 1
- 108010002352 Interleukin-1 Proteins 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000007969 cellular immunity Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000002297 mitogenic effect Effects 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
NUEVO DERIVADO DE GLUCOPIRANOSA DE FORMULA GENERAL (I), EN LA QUE R1 REPRESENTA UN ATOMO DE H, UN GRUPO OH O ALCOXI DE 1 A 4 C; R2 REPRESENTA LOS GRUPOS A, B, D O E ( EN CADA FORMULA T Y Q REPRESENTAN CADA UNO UN ENTERO DE 11 A 15, M'' ES UN NUMERO DE 6 A 12, N UN ENTERO DE 6 A 10 Y T'' Y N'' UN ENTERO DE 9 A 13; G REPRESENTA UN ENLACE SENCILLO O UN GRUPO ALQUILENO DE Y A 4 C; R2A REPRESENTA UN ATOMO DE H, UN GRUPO ALQUILO O ALCOXI DE 1 A 7 C O UN ATOMO DE HALOGENO); R3 REPRESENTA DIVERSOS GRUPOS QUE SE INDICAN Y R4 REPRESENTA UN ATOMO DE H O UN GRUPO HIDROXIMETILO O SULFOXIMETILO; O SUS SALES NO-TOXICAS QUE POSEEN ACTIVIDAD REFORZADORA DE LA INMUNIDAD CELULAR ( POR EJEMPLO ACTIVIDAD MITOGENICA) DE TEJIDOS VIVOS, POR LO QUE PUEDEN SER UTILES COMO AGENTES MEJORADORES DE LA INMUNIDAD Y POSEEN ACTIVIDAD INDUCTORA DE TNF, DE IL-1 Y DE IFN Y POR ELLO SE PUEDEN EMPLEAR COMO AGENTES ANTITUMORALES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10629887 | 1987-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2061544T3 true ES2061544T3 (es) | 1994-12-16 |
Family
ID=14430121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88106313T Expired - Lifetime ES2061544T3 (es) | 1987-05-01 | 1988-04-20 | Nuevos derivados de glucopiranosa. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0288888B1 (es) |
| JP (1) | JP2514070B2 (es) |
| KR (1) | KR960015408B1 (es) |
| AT (1) | ATE98250T1 (es) |
| DE (1) | DE3886085T2 (es) |
| ES (1) | ES2061544T3 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0655749B2 (ja) * | 1989-09-20 | 1994-07-27 | 日本たばこ産業株式会社 | リピッドａ単糖類縁体 |
| EP0482206A4 (en) * | 1990-04-12 | 1992-08-19 | Japan Tobacco Inc. | 4,6-o-hydroxyphosphorylglucosamine derivative |
| KR20010043248A (ko) * | 1998-05-06 | 2001-05-25 | 우에노 도시오 | 글루코피라노스 유도체를 유효 성분으로 하는 면역 억제제 |
| KR100824449B1 (ko) * | 2006-12-22 | 2008-04-23 | (주)디티브이인터랙티브 | Ｄｍｂ 수신기의 정상동작 검출용 방송 신호발생기 및정상동작 검출시스템 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4374831A (en) * | 1981-12-28 | 1983-02-22 | American Cyanamid Company | Modulators of the complement system comprising bis-glucopyranosyl arylene sulfate derivatives |
| EP0143840B1 (en) * | 1983-05-06 | 1990-08-29 | Wisconsin Alumni Research Foundation | Monosaccharide compounds having immunostimulating activity |
| ATE72443T1 (de) * | 1985-12-06 | 1992-02-15 | Ono Pharmaceutical Co | Glucopyranose-derivate. |
-
1988
- 1988-04-20 AT AT88106313T patent/ATE98250T1/de not_active IP Right Cessation
- 1988-04-20 DE DE3886085T patent/DE3886085T2/de not_active Expired - Fee Related
- 1988-04-20 ES ES88106313T patent/ES2061544T3/es not_active Expired - Lifetime
- 1988-04-20 EP EP88106313A patent/EP0288888B1/en not_active Expired - Lifetime
- 1988-04-30 KR KR1019880005006A patent/KR960015408B1/ko not_active Expired - Fee Related
- 1988-05-02 JP JP63107702A patent/JP2514070B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE98250T1 (de) | 1993-12-15 |
| DE3886085D1 (de) | 1994-01-20 |
| JP2514070B2 (ja) | 1996-07-10 |
| EP0288888B1 (en) | 1993-12-08 |
| DE3886085T2 (de) | 1994-06-23 |
| KR880013963A (ko) | 1988-12-22 |
| EP0288888A3 (en) | 1990-08-16 |
| EP0288888A2 (en) | 1988-11-02 |
| JPS6452793A (en) | 1989-02-28 |
| KR960015408B1 (ko) | 1996-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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