ES2063347T3 - Deposicion catalizada de indicador. - Google Patents

Deposicion catalizada de indicador.

Info

Publication number
ES2063347T3
ES2063347T3 ES90905997T ES90905997T ES2063347T3 ES 2063347 T3 ES2063347 T3 ES 2063347T3 ES 90905997 T ES90905997 T ES 90905997T ES 90905997 T ES90905997 T ES 90905997T ES 2063347 T3 ES2063347 T3 ES 2063347T3
Authority
ES
Spain
Prior art keywords
analyte
informer
analytic
deposit
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90905997T
Other languages
English (en)
Inventor
Mark Norman Bobrow
Richard Calvin Ebersole
Gerald Joseph Litt
John Richard Moran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of ES2063347T3 publication Critical patent/ES2063347T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA PRESENTE INVENCION ESTA RELACIONADA CON UN METODO PARA CATALIZAR LA DEPOSICION DE INFORMADOR Y MEJORAR LA DETECCION O CUANTIFICACION DE UN ANALITO EN UNA MUESTRA AMPLIANDO LA SEÑAL DETECTORA QUE COMPRENDE LA INMOVILIZACION DE UN SISTEMA DE ACTIVACION DE ENZIMAS ANALITO-DEPENDIENTES QUE CATALIZA LA DEPOSICION DEL INFORMADOR ACTIVANDO UN CONJUGADO FORMADO POR UN SUSTRATO ETIQUETADO DEFECTIBLEMENTE ESPECIFICO PARA EL SISTEMA ENZIMATICO, DICHO CONJUGADO REACCIONA CON EL SISTEMA DE ACTIVACION DE ENZIMAS ANALITO-DEPENDIENTES PARA FORMAR UN CONJUGADO ACTIVADO QUE SE DEPOSITA SUSTANCIALMENTE DONDE SE INMOVILICE EL RECEPTOR PARA EL CONJUGADO ACTIVADO, NO SIENDO REACTIVO DICHO RECEPTOR RESPECTO ALSISTEMA DE ACTIVACION DE ENZIMAS ANALITO-DEPENDIENTES. EN OTRA REALIZACION, LA INVENCION ESTA RELACIONADA CON UN ENSAYO PARA DETECTAR O CUANTIFICAR LA PRESENCIA O AUSENCIA DE UN ANALITO EN UNA MUESTRA UTILIZANDO LA DEPOSICION CATALIZADA DE INFORMADOR PARA AMPLIAR LA SEÑAL DEL INFORMADOR. TAMBIEN SE DESCRIBEN COMPUESTOS NUEVOS QUE SE PUEDEN UTILIZAR COMO REACTIVOS PARA PREPARAR CONJUGADOS TIPO HABA.
ES90905997T 1989-03-29 1990-03-28 Deposicion catalizada de indicador. Expired - Lifetime ES2063347T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33035789A 1989-03-29 1989-03-29
US49422690A 1990-03-20 1990-03-20

Publications (1)

Publication Number Publication Date
ES2063347T3 true ES2063347T3 (es) 1995-01-01

Family

ID=26987247

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90905997T Expired - Lifetime ES2063347T3 (es) 1989-03-29 1990-03-28 Deposicion catalizada de indicador.

Country Status (7)

Country Link
EP (1) EP0465577B1 (es)
JP (1) JP2948904B2 (es)
AU (1) AU645491B2 (es)
DE (1) DE69007473T2 (es)
ES (1) ES2063347T3 (es)
RU (1) RU2102759C1 (es)
WO (1) WO1990011523A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0795610A1 (en) * 1996-03-13 1997-09-17 Becton, Dickinson and Company In situ hybridization signal amplification based on biotinylated tyramine deposition
GB9712818D0 (en) * 1996-07-08 1997-08-20 Cambridge Antibody Tech Labelling and selection of specific binding molecules
EP0996855A4 (en) * 1997-06-04 2001-08-01 Au Membrane & Biotech Res Inst BIOSENSOR USING OPTICALLY SENSITIVE PARTS
DE10015418C2 (de) * 2000-03-28 2001-04-19 Eisenblaetter Gerd Gmbh Schleifwerkzeug und Verfahren zu dessen Herstellung
RU2197732C1 (ru) * 2001-05-30 2003-01-27 Государственный научно-исследовательский институт биологического приборостроения Способ обнаружения и идентификации клеток микроорганизмов и вирусов
RU2213974C1 (ru) * 2002-04-09 2003-10-10 Баженов Алексей Иванович Способ одновременного определения нескольких аналитов
US8758989B2 (en) * 2006-04-06 2014-06-24 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
JP5744743B2 (ja) 2008-11-17 2015-07-08 ヘッドウェイ テクノロジーズ, インク.Headway Technologies, Inc. 共有結合形成反応ペアを用いた標的分子の粒子ベースの検出における方法および組成物
JP5850746B2 (ja) 2008-11-17 2016-02-03 ヘッドウェイ テクノロジーズ, インク.Headway Technologies, Inc. 連結分子を用いた標的分子の粒子ベースの検出における方法および組成物
WO2012112563A2 (en) 2011-02-16 2012-08-23 Magic Technologies, Inc. Methods and compositions for the target-localized anchoring of detectable label
ES2678211T3 (es) 2012-03-27 2018-08-09 Ventana Medical Systems, Inc. Conjugados de señalización y procedimientos de uso
TWI653449B (zh) 2018-01-31 2019-03-11 國立交通大學 光子晶體與磁珠結合的螢光免疫檢測裝置和方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984002193A1 (en) * 1982-12-03 1984-06-07 Du Pont Chromogenic support immunoassay
DK147184A (da) * 1983-04-18 1984-10-19 Du Pont Fremgangsmaade og reagens til kvantitativ immunokemisk analyse
IL72269A0 (en) * 1983-11-30 1984-10-31 Miles Lab Specific binding assay methods and reagent systems

Also Published As

Publication number Publication date
EP0465577B1 (en) 1994-03-16
AU5410190A (en) 1990-10-22
RU2102759C1 (ru) 1998-01-20
DE69007473T2 (de) 1994-07-21
AU645491B2 (en) 1994-01-20
JPH04504206A (ja) 1992-07-30
WO1990011523A3 (en) 1991-02-21
WO1990011523A2 (en) 1990-10-04
DE69007473D1 (de) 1994-04-21
EP0465577A1 (en) 1992-01-15
JP2948904B2 (ja) 1999-09-13

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