ES2063858T3 - Preparacion del acido estearidonico. - Google Patents
Preparacion del acido estearidonico.Info
- Publication number
- ES2063858T3 ES2063858T3 ES90109553T ES90109553T ES2063858T3 ES 2063858 T3 ES2063858 T3 ES 2063858T3 ES 90109553 T ES90109553 T ES 90109553T ES 90109553 T ES90109553 T ES 90109553T ES 2063858 T3 ES2063858 T3 ES 2063858T3
- Authority
- ES
- Spain
- Prior art keywords
- stearidonic acid
- fatty acids
- preparation
- reinjection
- saponification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- OPGOLNDOMSBSCW-CLNHMMGSSA-N Fursultiamine hydrochloride Chemical compound Cl.C1CCOC1CSSC(\CCO)=C(/C)N(C=O)CC1=CN=C(C)N=C1N OPGOLNDOMSBSCW-CLNHMMGSSA-N 0.000 title abstract 4
- JIWBIWFOSCKQMA-UHFFFAOYSA-N stearidonic acid Natural products CCC=CCC=CCC=CCC=CCCCCC(O)=O JIWBIWFOSCKQMA-UHFFFAOYSA-N 0.000 title abstract 4
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- 150000004665 fatty acids Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000001435 Thromboembolism Diseases 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 239000003480 eluent Substances 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000004007 reversed phase HPLC Methods 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
- C11C1/007—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids using organic solvents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Fats And Perfumes (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PARA PREPARAR ACIDO ESTEARIDONICO A PARTIR DE UNA MEZCLA DE ACIDOS GRASOS QUE PORVIENEN DE LA SAPONIFICACION DE UN LIPIDO QUE LA CONTIENE, SE UTILIZA CROMATOGRAFIA LIQUIDA DE ALTA RESOLUCION EN FASE INVERSA ELIGIENDO LA COMPOSICION DE ELUYENTE Y LA CONCENTRACION DE LOS ACIODS GRASOS EN LAS DISOLUCIONES INYECTADAS EN LA COLUMNA. UNA REINYECCION DE LA FRACCION ENRIQUECIDA OBTENIDA CONDUCE AL ACIDO ESTEARIDONICO DE 98 % DE PUREZA. EL ACIDO ESTEARIDONICO ENTRA EN LA FORMULACION DE COMPOSICIONES FARMACEUTICAS CONTRA LAS ENFERMEDADES CARDIOVASCULARES Y TROMBO-EMBOLICAS ASOCIADAS A LA AGREGACION PLAQUETARIA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1919/89A CH678181A5 (es) | 1989-05-22 | 1989-05-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2063858T3 true ES2063858T3 (es) | 1995-01-16 |
Family
ID=4221649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90109553T Expired - Lifetime ES2063858T3 (es) | 1989-05-22 | 1990-05-19 | Preparacion del acido estearidonico. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5130449A (es) |
| EP (1) | EP0399417B1 (es) |
| AT (1) | ATE112760T1 (es) |
| AU (1) | AU626082B2 (es) |
| CH (1) | CH678181A5 (es) |
| DE (1) | DE69013216T2 (es) |
| DK (1) | DK0399417T3 (es) |
| ES (1) | ES2063858T3 (es) |
| ZA (1) | ZA903455B (es) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5234952A (en) * | 1988-12-23 | 1993-08-10 | Nestec S.A. | Reduction of thrombogenicity with lipids of blackcurrant seed |
| FR2679109B1 (fr) * | 1991-07-18 | 1994-03-11 | Institut Recherche Biologique Sa | Nouveaux complements nutritionnels ou dietetiques anti-vieillissement a base d'acide gras poly-insature. |
| JPH08512336A (ja) * | 1993-04-29 | 1996-12-24 | ノルスク・ヒドロ・アクシェセルスカープ | 脂肪酸およびその誘導体のクロマトグラフィーによる分画方法 |
| EP0682006B1 (fr) * | 1994-05-09 | 1999-04-07 | Societe Des Produits Nestle S.A. | Procédé de préparation d'un concentrat d'esters d'acides gras polyinsaturés |
| ES2203806T3 (es) * | 1996-06-03 | 2004-04-16 | Croda International Plc | Compuestos y usos de los mismos. |
| US6340485B1 (en) | 1996-06-03 | 2002-01-22 | Croda International Plc | Compositions and uses thereof |
| AU731692C (en) * | 1996-10-11 | 2001-10-11 | Scarista Limited | Pharmaceutical preparation comprising eicosapentaenoic acid and/or stearidonic acid |
| US6149964A (en) * | 1998-05-21 | 2000-11-21 | Beech-Nut Nutrition Corporation | Egg yolk-containing baby food compositions and methods therefor |
| US7413759B2 (en) * | 1998-05-21 | 2008-08-19 | Beech-Nut Nutrition Corporation | Method of enhancing cognitive ability in infant fed DHA containing baby-food compositions |
| US7141266B2 (en) * | 1998-05-21 | 2006-11-28 | Beech-Nut Nutrition Corporation | Baby-food compositions enhancing visual acuity and methods therefor |
| US6579551B1 (en) | 1998-05-21 | 2003-06-17 | Beech-Nut Nutrition Corporation | Baby-food compositions containing egg yolk and methods therefor |
| DE60012934T2 (de) | 1999-02-26 | 2005-08-25 | Martek Biosciences Corp. | Verfahren zum Abtrennen von einem Docosahexaensäure enthaltenden Triglycerid aus einem Triglyceridgemisch |
| US6395778B1 (en) | 2000-01-11 | 2002-05-28 | Omegatech, Inc. | Process for making an enriched mixture of polyunsaturated fatty acid esters |
| FR2804023B1 (fr) * | 2000-01-26 | 2002-09-20 | Johnson & Johnson Consumer Fr | Complement nutritionnel a base d'huile de pepins de cassis |
| KR20010008387A (ko) * | 2000-11-30 | 2001-02-05 | 이성권 | 결정화방법을 이용한 고순도 불포화지방산의 분리 정제 방법 |
| EP1489915A4 (en) * | 2002-03-08 | 2005-09-14 | Monsanto Technology Llc | TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES |
| EP2295529B2 (en) * | 2002-07-11 | 2022-05-18 | Basf As | Use of a volatile environmental pollutants-decreasing working fluid for decreasing the amount of pollutants in a fat for alimentary or cosmetic use |
| SE0202188D0 (sv) * | 2002-07-11 | 2002-07-11 | Pronova Biocare As | A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product |
| CA2881252C (en) * | 2003-08-21 | 2017-02-28 | Monsanto Technology Llc | Soybean oil having 5 to 50% sda and less than 10% gla |
| EP1734947B1 (en) | 2004-04-16 | 2015-04-15 | Monsanto Technology, LLC | Expression of fatty acid desaturases in corn |
| US20050266051A1 (en) * | 2004-05-27 | 2005-12-01 | The Procter & Gamble Company | Pet food compositions and methods |
| WO2006052664A2 (en) | 2004-11-04 | 2006-05-18 | Monsanto Technology Llc | Processes for preparation of oil compositions |
| WO2007103160A2 (en) * | 2006-03-03 | 2007-09-13 | Monsanto Technology Llc | Stearidonic acid for improving cardiovascular health |
| AR059811A1 (es) | 2006-03-10 | 2008-04-30 | Monsanto Technology Llc | Semillas de soja, composiciones de soja, y metodos para producirlas |
| US8060617B2 (en) * | 2008-12-19 | 2011-11-15 | Cisco Technology, Inc. | Reserving network resources during scheduling of meeting event |
| US9480271B2 (en) | 2009-09-15 | 2016-11-01 | Monsanto Technology Llc | Soybean seed and oil compositions and methods of making same |
| US8372465B2 (en) * | 2010-02-17 | 2013-02-12 | Bunge Oils, Inc. | Oil compositions of stearidonic acid |
| WO2024262581A1 (ja) * | 2023-06-22 | 2024-12-26 | 株式会社ニッスイ | 高度不飽和脂肪酸エステル組成物の製造方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4701468A (en) * | 1983-04-15 | 1987-10-20 | Roussel-Uclaf | Oxidized triglycerides having therapeutic utility |
| CH663951A5 (fr) * | 1984-10-10 | 1988-01-29 | Nestle Sa | Procede d'enrichissement selectif en acides gras polyinsatures d'un melange contenant des acides gras fractions enrichies obtenues et compositions les contenant. |
| CH669208A5 (fr) * | 1986-12-17 | 1989-02-28 | Nestle Sa | Procede de fractionnement en continu d'un melange d'acides gras. |
-
1989
- 1989-05-22 CH CH1919/89A patent/CH678181A5/fr not_active IP Right Cessation
-
1990
- 1990-05-03 AU AU54748/90A patent/AU626082B2/en not_active Ceased
- 1990-05-07 ZA ZA903455A patent/ZA903455B/xx unknown
- 1990-05-09 US US07/521,311 patent/US5130449A/en not_active Expired - Fee Related
- 1990-05-19 DE DE69013216T patent/DE69013216T2/de not_active Expired - Fee Related
- 1990-05-19 DK DK90109553.9T patent/DK0399417T3/da not_active Application Discontinuation
- 1990-05-19 AT AT90109553T patent/ATE112760T1/de not_active IP Right Cessation
- 1990-05-19 EP EP90109553A patent/EP0399417B1/fr not_active Expired - Lifetime
- 1990-05-19 ES ES90109553T patent/ES2063858T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0399417A3 (fr) | 1992-01-22 |
| CH678181A5 (es) | 1991-08-15 |
| EP0399417B1 (fr) | 1994-10-12 |
| DE69013216T2 (de) | 1995-03-02 |
| US5130449A (en) | 1992-07-14 |
| ZA903455B (en) | 1991-02-27 |
| DK0399417T3 (da) | 1995-02-06 |
| EP0399417A2 (fr) | 1990-11-28 |
| ATE112760T1 (de) | 1994-10-15 |
| AU626082B2 (en) | 1992-07-23 |
| DE69013216D1 (de) | 1994-11-17 |
| AU5474890A (en) | 1990-11-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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