ES2069201T3 - Una via para la preparacion de glicales en las series alal y gulal. - Google Patents

Una via para la preparacion de glicales en las series alal y gulal.

Info

Publication number
ES2069201T3
ES2069201T3 ES91302544T ES91302544T ES2069201T3 ES 2069201 T3 ES2069201 T3 ES 2069201T3 ES 91302544 T ES91302544 T ES 91302544T ES 91302544 T ES91302544 T ES 91302544T ES 2069201 T3 ES2069201 T3 ES 2069201T3
Authority
ES
Spain
Prior art keywords
gulal
series
glicales
alal
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91302544T
Other languages
English (en)
Inventor
Randall L Halcomb
Samuel J Danishefsky
Mark D Wittman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University filed Critical Yale University
Application granted granted Critical
Publication of ES2069201T3 publication Critical patent/ES2069201T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Vehicle Body Suspensions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Ceramic Products (AREA)

Abstract

SULFOXIDAS ANOMERICOS AXIALES GENERADOS MEDIANTE AJUSTES TIOFENOL FERRIER DE DERIVADOS DE GLUCOL Y GALACTAL SE UTILIZAN PARA SINTETIZAR GLICOLES DE LAS SERIES GULAL Y ALLAL. UNA APLICACION DEL METODO CONDUCE A LA SINTESIS DEL TIOGUCIDO ESPERAMICIN.
ES91302544T 1990-03-23 1991-03-22 Una via para la preparacion de glicales en las series alal y gulal. Expired - Lifetime ES2069201T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/498,262 US5104982A (en) 1990-03-23 1990-03-23 Route to glycals in the allal and gulal series

Publications (1)

Publication Number Publication Date
ES2069201T3 true ES2069201T3 (es) 1995-05-01

Family

ID=23980287

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91302544T Expired - Lifetime ES2069201T3 (es) 1990-03-23 1991-03-22 Una via para la preparacion de glicales en las series alal y gulal.

Country Status (9)

Country Link
US (2) US5104982A (es)
EP (1) EP0448412B1 (es)
JP (1) JPH0680657A (es)
AT (1) ATE118491T1 (es)
CA (1) CA2037754A1 (es)
DE (1) DE69107316T2 (es)
DK (1) DK0448412T3 (es)
ES (1) ES2069201T3 (es)
GR (1) GR3015115T3 (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1603609A (en) * 1977-04-14 1981-11-25 Chembiomed Ltd O-protected 2-azido-2-deoxy-glycosyl nitrates
US4362720A (en) * 1977-04-14 1982-12-07 Chembiomed Ltd. Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
US4935503A (en) * 1988-05-05 1990-06-19 Biomira, Inc. Azidochlorination and diazidization of glycals

Also Published As

Publication number Publication date
DK0448412T3 (da) 1995-07-24
EP0448412A2 (en) 1991-09-25
US5278301A (en) 1994-01-11
JPH0680657A (ja) 1994-03-22
EP0448412B1 (en) 1995-02-15
GR3015115T3 (en) 1995-05-31
US5104982A (en) 1992-04-14
ATE118491T1 (de) 1995-03-15
CA2037754A1 (en) 1991-09-24
DE69107316D1 (de) 1995-03-23
EP0448412A3 (en) 1991-11-13
DE69107316T2 (de) 1995-07-13

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