ES2069272T3 - Hexapeptidos con grupos esteres sulfato. - Google Patents

Hexapeptidos con grupos esteres sulfato.

Info

Publication number
ES2069272T3
ES2069272T3 ES91901058T ES91901058T ES2069272T3 ES 2069272 T3 ES2069272 T3 ES 2069272T3 ES 91901058 T ES91901058 T ES 91901058T ES 91901058 T ES91901058 T ES 91901058T ES 2069272 T3 ES2069272 T3 ES 2069272T3
Authority
ES
Spain
Prior art keywords
elevated
ala
pro
sub
square
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91901058T
Other languages
English (en)
Inventor
James Donald Rosamond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Corp
Original Assignee
Fisons Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Corp filed Critical Fisons Corp
Application granted granted Critical
Publication of ES2069272T3 publication Critical patent/ES2069272T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/595Gastrins; Cholecystokinins [CCK]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/595Gastrins; Cholecystokinins [CCK]
    • C07K14/5955Gastrins; Cholecystokinins [CCK] at least 1 amino acid in D-form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Led Devices (AREA)
  • Hydroponics (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

COMPUESTOS DE LA FORMULA (I), EN DONDE M ES MET, DMET, MEMET, METO, AHX, DAHX, MEAHX, LEU, MELEU, PRO, ILE, MEILE, ALA O LYS; G ES GLY, DALA, PRO, ALA, (BETA)ALA O SAR; W ES TRP, METRP, ALA O NAL; X ES MET, MEMET, METO, AHX, MEAHX, LEU, MELEU, PRO, ILE, MEILE, ALA O LYS; J ES ASP, DASP, MEASP, ALA O ASN; F ELEVADO 1 ES (S)-NH, (R)-NH, (S)-R ELEVADO 1N O (R)-R (AL CUADRADO) N; F (AL CUADRADO) ES H , CL, I, BR, F, NO SUB 2, NH SUB 2, R ELEVADO 3 O OR ELEVADO 4; Z ES NH SUB 2, NHR ELEVADO 5 O NR ELEVADO 5R ELEVADO 6; R ELEVADO 1, R (AL CUADRADO) , R ELEVADO 3, R ELEVADO 5 Y R ELEVADO 6 SON C1 A 6 ALQUILO; Y R ELEVADO 4 ES H O C1 A 6 ALQUILO Y LAS SALES FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS, QUE SON NUEVOS Y UTILES COMO PRODUCTOS FARMACEUTICOS. EN PARTICULAR, SON UTILES PARA EL TRATAMIENTO DE LA OBESIDAD Y PARA ESTIMULAR LA CONTRACCION DE LA VESICULA BILIAR.
ES91901058T 1989-11-27 1990-11-16 Hexapeptidos con grupos esteres sulfato. Expired - Lifetime ES2069272T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44127589A 1989-11-27 1989-11-27

Publications (1)

Publication Number Publication Date
ES2069272T3 true ES2069272T3 (es) 1995-05-01

Family

ID=23752246

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91901058T Expired - Lifetime ES2069272T3 (es) 1989-11-27 1990-11-16 Hexapeptidos con grupos esteres sulfato.

Country Status (19)

Country Link
EP (1) EP0495013B1 (es)
JP (1) JPH05500962A (es)
KR (1) KR927003630A (es)
AT (1) ATE119544T1 (es)
AU (1) AU644128B2 (es)
CA (1) CA2030720A1 (es)
DE (1) DE69017704T2 (es)
DK (1) DK0495013T3 (es)
ES (1) ES2069272T3 (es)
FI (1) FI922404L (es)
HU (2) HU00168A9 (es)
IE (1) IE66837B1 (es)
IL (1) IL96465A (es)
LV (1) LV11623A (es)
NO (1) NO922094L (es)
NZ (1) NZ236167A (es)
PT (1) PT95996B (es)
WO (1) WO1991008225A1 (es)
ZA (1) ZA909415B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5502164A (en) * 1989-11-27 1996-03-26 Fisons Corporation Peptide compounds having therapeutic activity
MX9207458A (es) * 1991-12-20 1993-11-01 Fisons Corp Compuestos de peptido que tienen actividad terapeutica.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6915336D0 (pt) * 1969-05-27 1973-03-13 Squibb & Sons Inc Reptidios contendo tirosina-o-sulfato
DD128973B1 (de) * 1976-11-29 1979-11-28 Hartmut Niedrich Verfahren zur herstellung von peptiden,die tyrosinsulfat enthalten
US4217353A (en) * 1978-05-19 1980-08-12 E. I. Du Pont De Nemours And Company Method for inducing anorexia
NZ218607A (en) * 1985-12-19 1989-10-27 Pennwalt Corp Tri-to acta-peptides with sulphate ester groups: obesity treatment
US5086042A (en) * 1985-12-19 1992-02-04 Fisons Corporation Peptides with sulfate ester groups
IE873084L (en) * 1986-11-18 1988-05-18 Pfizer Hospital Prod Peptides with sulfate ester groups
US4808701A (en) * 1987-03-30 1989-02-28 Hoffmann-La Roche Inc. Cyclic peptides having appetite regulating activity

Also Published As

Publication number Publication date
CA2030720A1 (en) 1991-05-28
IE904239A1 (en) 1991-06-05
FI922404A7 (fi) 1992-05-26
AU6964491A (en) 1991-06-26
WO1991008225A1 (en) 1991-06-13
AU644128B2 (en) 1993-12-02
HU211694A9 (en) 1995-12-28
NO922094D0 (no) 1992-05-26
NO922094L (no) 1992-07-08
JPH05500962A (ja) 1993-02-25
IL96465A (en) 1994-12-29
PT95996B (pt) 1998-01-30
ATE119544T1 (de) 1995-03-15
DE69017704D1 (de) 1995-04-13
DE69017704T2 (de) 1995-07-20
EP0495013A1 (en) 1992-07-22
HU00168A9 (en) 1995-07-28
PT95996A (pt) 1991-09-13
FI922404A0 (fi) 1992-05-26
KR927003630A (ko) 1992-12-18
DK0495013T3 (da) 1995-07-24
LV11623A (lv) 1996-12-20
FI922404L (fi) 1992-05-26
NZ236167A (en) 1991-12-23
ZA909415B (en) 1991-11-27
EP0495013B1 (en) 1995-03-08
IE66837B1 (en) 1996-02-07
IL96465A0 (en) 1991-08-16

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