ES2069894T3 - Una preparacion anticoagulante. - Google Patents
Una preparacion anticoagulante.Info
- Publication number
- ES2069894T3 ES2069894T3 ES91912208T ES91912208T ES2069894T3 ES 2069894 T3 ES2069894 T3 ES 2069894T3 ES 91912208 T ES91912208 T ES 91912208T ES 91912208 T ES91912208 T ES 91912208T ES 2069894 T3 ES2069894 T3 ES 2069894T3
- Authority
- ES
- Spain
- Prior art keywords
- epi
- anticoagulant preparation
- anticoagulant
- preparation
- mucopolisacaride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 229940127219 anticoagulant drug Drugs 0.000 title 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000001112 coagulating effect Effects 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Shaping By String And By Release Of Stress In Plastics And The Like (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Materials For Medical Uses (AREA)
Abstract
PARA LA PROFILAXIS O EL TRATAMIENTO DE ENFERMEDADES DE LA COAGULACION O DEL CANCER SE ADMINISTRA UN INHIBIDOR DE LA LINEA EXTRINSICA (EPI) JUNTO CON HEPARINA U OTRO MUCOPOLISACARIDO AL PACIENTE. DE ESTA FORMA SE OBTIENE UNA ACTIVIDAD COAGULANTE INCREMENTADA ASI COMO UN INCREMENTO DE LA VIDA MEDIA DEL EPI INYECTADO EN EL PLASMA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK148890A DK148890D0 (da) | 1990-06-19 | 1990-06-19 | Farmaceutisk praeparat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2069894T3 true ES2069894T3 (es) | 1995-05-16 |
Family
ID=8105367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91912208T Expired - Lifetime ES2069894T3 (es) | 1990-06-19 | 1991-05-30 | Una preparacion anticoagulante. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0535129B1 (es) |
| JP (1) | JP3362038B2 (es) |
| AT (1) | ATE119781T1 (es) |
| AU (1) | AU645581B2 (es) |
| BG (1) | BG61181B1 (es) |
| CA (1) | CA2085101A1 (es) |
| DE (1) | DE69108242T2 (es) |
| DK (2) | DK148890D0 (es) |
| ES (1) | ES2069894T3 (es) |
| HU (1) | HU221323B1 (es) |
| WO (1) | WO1991019514A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6291427B1 (en) | 1990-08-27 | 2001-09-18 | G.D. Searle & Co. | Anticoagulant combination of LACI and sulfated polysaccharides |
| US5849703A (en) * | 1990-08-27 | 1998-12-15 | G. D. Searle & Co. | Pre-formed anticoagulant heparin/TFPI complexes |
| DK261490D0 (da) * | 1990-10-31 | 1990-10-31 | Novo Nordisk As | New pharmaceutical compound |
| US5276015A (en) * | 1992-03-18 | 1994-01-04 | Washington University | Method of inhibiting microvascular thrombosis |
| US20030171292A1 (en) | 1992-06-01 | 2003-09-11 | Creasey Abla A. | Method for using lipoprotein associated coagulation inhibitor to treat sepsis |
| US6063764A (en) * | 1992-06-01 | 2000-05-16 | Washington University & Chiron Corp. | Method for using lipoprotein associated coagulation inhibitor to treat sepsis |
| KR950701820A (ko) * | 1992-06-11 | 1995-05-17 | 로저 에이. 윌리암스 | 패혈증 및 패혈증-연관 옹고장애의 예방 및 치료(prophylaxs and treatment of sepsis and sepsis-associated coagulation disorders) |
| ZA941414B (en) * | 1993-03-02 | 1994-09-28 | Novo Nordisk A G | Non-glycosylated TFPI analogues |
| US5981471A (en) * | 1997-02-06 | 1999-11-09 | Entremed, Inc. | Compositions and methods for inhibiting cellular proliferation |
| EA200400548A1 (ru) | 2001-10-15 | 2005-06-30 | Чирон Корпорейшн | Лечение тяжёлой пневмонии путём введения ингибитора пути тканевого фактора (tfpi) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3170001D1 (en) * | 1980-09-30 | 1985-05-23 | Bayer Ag | Method for the production of an antithrombin-heparin complex and pharmaceutical compositions containing the complex |
| US4689323A (en) * | 1983-09-26 | 1987-08-25 | Miles Laboratories, Inc. | Covalently bound heparin--antithrombin-III complex |
| IL79255A0 (en) * | 1986-06-26 | 1986-09-30 | Hadassah Med Org | Composition for metastasis prevention |
| US4900723A (en) * | 1988-04-29 | 1990-02-13 | E. R. Squibb & Sons, Inc. | Method of preventing or reducing venous thrombosis using a thromboxane A2 receptor antagonist in conjunction with heparin and combination |
| DK408089D0 (da) * | 1989-08-18 | 1989-08-18 | Novo Nordisk As | Proteiner |
-
1990
- 1990-06-19 DK DK148890A patent/DK148890D0/da not_active Application Discontinuation
-
1991
- 1991-05-30 DE DE69108242T patent/DE69108242T2/de not_active Expired - Fee Related
- 1991-05-30 DK DK91912208.5T patent/DK0535129T3/da active
- 1991-05-30 AT AT91912208T patent/ATE119781T1/de not_active IP Right Cessation
- 1991-05-30 CA CA002085101A patent/CA2085101A1/en not_active Abandoned
- 1991-05-30 JP JP51133391A patent/JP3362038B2/ja not_active Expired - Fee Related
- 1991-05-30 WO PCT/DK1991/000145 patent/WO1991019514A1/en not_active Ceased
- 1991-05-30 AU AU80604/91A patent/AU645581B2/en not_active Ceased
- 1991-05-30 HU HU9204036A patent/HU221323B1/hu not_active IP Right Cessation
- 1991-05-30 ES ES91912208T patent/ES2069894T3/es not_active Expired - Lifetime
- 1991-05-30 EP EP91912208A patent/EP0535129B1/en not_active Expired - Lifetime
-
1992
- 1992-12-18 BG BG97199A patent/BG61181B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2085101A1 (en) | 1991-12-20 |
| AU8060491A (en) | 1992-01-07 |
| ATE119781T1 (de) | 1995-04-15 |
| WO1991019514A1 (en) | 1991-12-26 |
| HUT63578A (en) | 1993-09-28 |
| EP0535129A1 (en) | 1993-04-07 |
| AU645581B2 (en) | 1994-01-20 |
| HU221323B1 (en) | 2002-09-28 |
| DK148890D0 (da) | 1990-06-19 |
| BG97199A (bg) | 1993-12-24 |
| JP3362038B2 (ja) | 2003-01-07 |
| BG61181B1 (bg) | 1997-02-28 |
| DE69108242D1 (de) | 1995-04-20 |
| DE69108242T2 (de) | 1995-07-06 |
| DK0535129T3 (da) | 1995-08-07 |
| HU9204036D0 (en) | 1993-03-29 |
| EP0535129B1 (en) | 1995-03-15 |
| JPH05507926A (ja) | 1993-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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