ES2070292T3 - Derivados de 4-amino cromano y de 4-amidino(3,2-c)-pirano piridina, procedimiento de obtencion y composiciones farmaceuticas que los contienen. - Google Patents

Derivados de 4-amino cromano y de 4-amidino(3,2-c)-pirano piridina, procedimiento de obtencion y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2070292T3
ES2070292T3 ES90403124T ES90403124T ES2070292T3 ES 2070292 T3 ES2070292 T3 ES 2070292T3 ES 90403124 T ES90403124 T ES 90403124T ES 90403124 T ES90403124 T ES 90403124T ES 2070292 T3 ES2070292 T3 ES 2070292T3
Authority
ES
Spain
Prior art keywords
sub
derivatives
obtaining
contain
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90403124T
Other languages
English (en)
Inventor
Georges Garcia
Patrick Gautier
Dino Nisato
Richard Roux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8914518A external-priority patent/FR2654103B1/fr
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of ES2070292T3 publication Critical patent/ES2070292T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A DERIVADOS DE AMIDINO-4 CROMANO Y DE AMIDINO-4 PIRANO [3, 2-C] PIRIDINA, A UN PROCESO PARA SU OBTENCION Y A LAS COMPOSICIONES FARMACEUTICAS QUE LAS CONTIENEN. DICHOS DERIVADOS TIENEN ACTIVIDADES DE ANTIHIPERTENSION Y DE ANTIARITMIA. RESPONDEN A LA FORMULA: EN LA QUE: A + B = -CH = CH-CH = NN O, C-Z R SUB 1 = H, CN, NO SUB 2, C SUB 1 OH, C SUB 1 2-, (VACIO) -SO SUB 2-; R SUB 2 = H R SUB 3 = OH O OCOCH SUB 3 O R SUB 2 + R SUB 3 = DOBLE ENLACE.
ES90403124T 1989-11-06 1990-11-06 Derivados de 4-amino cromano y de 4-amidino(3,2-c)-pirano piridina, procedimiento de obtencion y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2070292T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8914518A FR2654103B1 (fr) 1989-11-06 1989-11-06 Derives d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques les contenant.
FR909001258A FR2657872B2 (fr) 1989-11-06 1990-02-02 Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant.

Publications (1)

Publication Number Publication Date
ES2070292T3 true ES2070292T3 (es) 1995-06-01

Family

ID=26227645

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90403124T Expired - Lifetime ES2070292T3 (es) 1989-11-06 1990-11-06 Derivados de 4-amino cromano y de 4-amidino(3,2-c)-pirano piridina, procedimiento de obtencion y composiciones farmaceuticas que los contienen.

Country Status (21)

Country Link
US (2) US5116849A (es)
EP (1) EP0427606B1 (es)
JP (1) JPH07103117B2 (es)
KR (1) KR910009708A (es)
AR (1) AR248021A1 (es)
AT (1) ATE118004T1 (es)
AU (1) AU635080B2 (es)
CA (1) CA2029278A1 (es)
DE (1) DE69016592T2 (es)
DK (1) DK0427606T3 (es)
ES (1) ES2070292T3 (es)
FI (1) FI95249C (es)
FR (1) FR2657872B2 (es)
GR (1) GR3015684T3 (es)
HU (2) HU215111B (es)
IE (1) IE66726B1 (es)
IL (1) IL96168A (es)
MX (1) MX9203616A (es)
NO (1) NO176517C (es)
NZ (1) NZ235944A (es)
PT (1) PT95791A (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387587A (en) * 1986-12-23 1995-02-07 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
US5284838A (en) * 1987-06-23 1994-02-08 Elf Sanofi Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma
FR2657872B2 (fr) * 1989-11-06 1992-06-12 Sanofi Sa Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant.
ATE191716T1 (de) * 1992-08-17 2000-04-15 Chugai Pharmaceutical Co Ltd Benzopyran und benzoxazin-derivate
US5500442A (en) * 1994-06-10 1996-03-19 American Home Products Corporation Cyclobut-3-ene-1,2-dione derivatives as smooth muscle relaxants
US5470861A (en) * 1994-08-04 1995-11-28 Hoffmann-La Roche Inc. Method of promoting hair growth
GB2397054B (en) * 2003-01-07 2006-02-15 Jensen A collection bin for a laundry

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3682331D1 (de) * 1985-06-08 1991-12-12 Beecham Group Plc Pyrano(3,2-c)pyridinderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
FI90343C (fi) * 1987-06-23 1994-01-25 Merck Patent Gmbh Menetelmä korkeaa verenpainetta alentavien ja rytmihäiriöitä vastustavien trans-2,2-dimetyylikroman-3-olijohdannaisten valmistamiseksi
FR2621587B1 (fr) * 1987-10-12 1990-02-09 Sanofi Sa Derives du dimethyl-2,2 chromene, procede pour leur preparation et composition pharmaceutiques les contenant
GB8800199D0 (en) * 1988-01-06 1988-02-10 Beecham Group Plc Pharmaceutical preparation
US5021432A (en) * 1988-04-26 1991-06-04 Yoshitomi Pharmaceutical Industries, Ltd. Benzopyran compound and its pharmaceutical use
US4988723A (en) * 1988-06-02 1991-01-29 Fujisawa Pharmaceutical Co., Ltd. Benzopyran derivatives and their use as anti-hypertensives
DE3823533A1 (de) * 1988-07-12 1990-02-08 Beiersdorf Ag Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate
CA2015296C (en) * 1989-05-31 2001-08-07 Karnail Atwal Pyranyl cyanoguanidine derivatives
JP2906349B2 (ja) * 1989-11-01 1999-06-21 住友重機械工業株式会社 光ディスク基板の製造方法
FR2657872B2 (fr) * 1989-11-06 1992-06-12 Sanofi Sa Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant.
US5061813A (en) * 1990-04-02 1991-10-29 E. R. Squibb & Sons, Inc. Substituted cyanoimino benzopyranes

Also Published As

Publication number Publication date
NZ235944A (en) 1992-02-25
DE69016592T2 (de) 1995-08-03
FR2657872A2 (fr) 1991-08-09
GR3015684T3 (en) 1995-07-31
CA2029278A1 (en) 1991-05-27
IL96168A (en) 1995-03-15
KR910009708A (ko) 1991-06-28
NO176517B (no) 1995-01-09
EP0427606A1 (fr) 1991-05-15
HU215111B (hu) 1998-12-28
NO176517C (no) 1995-04-19
NO904805D0 (no) 1990-11-05
AU635080B2 (en) 1993-03-11
IL96168A0 (en) 1991-07-18
FI905445A0 (fi) 1990-11-02
HUT59395A (en) 1992-05-28
IE66726B1 (en) 1996-01-24
AR248021A1 (es) 1995-05-31
PT95791A (pt) 1991-09-13
JPH07103117B2 (ja) 1995-11-08
FI95249C (fi) 1996-01-10
MX9203616A (es) 1992-07-01
IE903975A1 (en) 1991-05-08
EP0427606B1 (fr) 1995-02-01
FR2657872B2 (fr) 1992-06-12
JPH03169878A (ja) 1991-07-23
US5225415A (en) 1993-07-06
HU211234A9 (en) 1995-11-28
DK0427606T3 (da) 1995-06-06
FI95249B (fi) 1995-09-29
US5116849A (en) 1992-05-26
ATE118004T1 (de) 1995-02-15
DE69016592D1 (de) 1995-03-16
NO904805L (no) 1991-05-07
AU6564490A (en) 1991-05-09
HU907000D0 (en) 1991-05-28

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