ES2070828T3 - Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma. - Google Patents

Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma.

Info

Publication number
ES2070828T3
ES2070828T3 ES87870039T ES87870039T ES2070828T3 ES 2070828 T3 ES2070828 T3 ES 2070828T3 ES 87870039 T ES87870039 T ES 87870039T ES 87870039 T ES87870039 T ES 87870039T ES 2070828 T3 ES2070828 T3 ES 2070828T3
Authority
ES
Spain
Prior art keywords
bacteria
protein production
ribosoma
stimulation
new linkage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87870039T
Other languages
English (en)
Inventor
Peter Olafs Olins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Application granted granted Critical
Publication of ES2070828T3 publication Critical patent/ES2070828T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA NUEVOS SITIOS DE UNION A RIBOSOMAS QUE SON UTILES PARA AUMENTAR LA PRODUCCION DE PROTEINAS EN BACTERIAS. TMBIEN SE PROPORCIONAN METODOS, GENES, BACTERIAS Y COMPUESTOS INTERMEDIOS UTILES QUE EMPLEAN LOS NUEVOS SITIOS DE UNION A RIBOSOMAS. TAMBIEN SE PROPORCIONA UN NUEVO SITIO DE INTERACCION DIFERENTE DE UNA SECUENCIA SHINE-DALGARNO ENTRE EL ARN RIBOSOMICO 16S Y EL ARN MENSAJERO.
ES87870039T 1986-03-27 1987-03-26 Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma. Expired - Lifetime ES2070828T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84515986A 1986-03-27 1986-03-27
US582187A 1987-02-04 1987-02-04

Publications (1)

Publication Number Publication Date
ES2070828T3 true ES2070828T3 (es) 1995-06-16

Family

ID=26674811

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87870039T Expired - Lifetime ES2070828T3 (es) 1986-03-27 1987-03-26 Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma.

Country Status (12)

Country Link
EP (1) EP0241446B1 (es)
JP (1) JP2511948B2 (es)
AT (1) ATE119200T1 (es)
AU (1) AU597951B2 (es)
CA (1) CA1340091C (es)
DE (1) DE3751100T2 (es)
DK (1) DK154487A (es)
ES (1) ES2070828T3 (es)
HU (1) HUT43625A (es)
IE (1) IE67890B1 (es)
IL (1) IL82017A (es)
NZ (1) NZ219789A (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2970811B2 (ja) * 1987-10-30 1999-11-02 オンコゲン ア リミテッド パートナーシップ 原核生物細胞中にポリペプチドを調製するための発現システム
US5268284A (en) * 1988-03-11 1993-12-07 The Upjohn Company Ribosome binding site
AU3341089A (en) * 1988-03-11 1989-10-05 Upjohn Company, The Ribosome binding site
JPH0213382A (ja) * 1988-03-30 1990-01-17 Monsanto Co グラムネガテイブ微生物での構造遺伝子の調節発現法
US5279947A (en) * 1988-08-24 1994-01-18 Sanofi DNA sequence participating in the regulation of the expression of a DNA sequence coding for a precursor of a polypeptide, expression vectors and process for the periplasmic production of the polypeptide
FR2636644B1 (fr) * 1988-08-24 1990-12-28 Sanofi Sa Sequence d'adn participant a la regulation de l'expression d'une sequence d'adn codant pour un precurseur d'un polypeptide, vecteurs d'expression et procede de production periplasmique du polypeptide
US5089473A (en) 1988-08-29 1992-02-18 Monsanto Company Somatotropin variants and their use
GR1002113B (en) * 1988-09-02 1996-02-02 Oncogen Expression systems for preparation of polypeptides in prokaryotic cells
US6271444B1 (en) 1998-07-10 2001-08-07 Calgene Llc Enhancer elements for increased translation in plant plastids
EP1022337B1 (en) * 1999-01-20 2006-07-26 Bayer HealthCare AG Plasmids, their construction and their use in the manufacture of interleukin-4 and interleukin-4 muteins
DE69929638T2 (de) 1999-01-20 2006-09-21 Bayer Healthcare Ag Plasmide, deren Konstruktion und Anwendung zur Herstellung von Interleukin-4 und dessen Muteine
JP2005230001A (ja) * 2004-01-20 2005-09-02 Mariusu:Kk リボソームｒｎａ塩基配列に相補的な１本鎖ｄｎａオリゴマーを用いたたんぱく質翻訳調節因子及びリボソームｒｎａ塩基配列に相補的な１本鎖ｄｎａオリゴマーを用いたイニシエーションファクター並びにリボソームｒｎａ塩基配列に相補的な１本鎖ｄｎａオリゴマーを用いたたんぱく質翻訳調節方法
WO2008091531A2 (en) * 2007-01-19 2008-07-31 Eli Lilly And Company Elements for improved expression of bovine somatotropin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
GR81701B (es) * 1983-01-18 1984-12-12 Lilly Co Eli
EP0178863A1 (en) * 1984-10-15 1986-04-23 Schering Corporation Novel expression systems utilizing bacteriophage T7 promoters and gene sequences
US5037806A (en) 1985-02-22 1991-08-06 Monsanto Company Biologically active method using somatotropins

Also Published As

Publication number Publication date
JP2511948B2 (ja) 1996-07-03
IE67890B1 (en) 1996-05-01
AU7066187A (en) 1987-10-01
ATE119200T1 (de) 1995-03-15
HUT43625A (en) 1987-11-30
DK154487A (da) 1987-12-21
NZ219789A (en) 1990-09-26
IL82017A0 (en) 1987-10-20
JPS63289A (ja) 1988-01-05
CA1340091C (en) 1998-10-20
DE3751100T2 (de) 1995-09-07
IE870782L (en) 1987-09-27
IL82017A (en) 1996-01-19
EP0241446B1 (en) 1995-03-01
AU597951B2 (en) 1990-06-14
EP0241446A2 (en) 1987-10-14
DK154487D0 (da) 1987-03-26
EP0241446A3 (en) 1988-11-09
DE3751100D1 (de) 1995-04-06

Similar Documents

Publication Publication Date Title
ES2070828T3 (es) Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma.
GR3030811T3 (en) Proteins produced by human lymphocytes, dna sequence coding these proteins, and pharmaceutical and biological uses thereof
ES2099096T3 (es) Una citoquina humana, la interleuquina 9.
BE891659A (fr) Molecules d'adn de recombinant et procedes d'obtention de proteines.
ATE377076T1 (de) Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen
IL112873A0 (en) Rapamycin-fkbp12 binding proteins their isolation and their use
NZ296748A (en) Peripheral nervous system specific sodium channel proteins, DNA coding therefor, compositions and methods
DK666888D0 (da) Human vaevsfaktor-relaterende dna-segmenter, polypeptider og antistoffer
EP0731636A4 (en) APOPTOSIS-MODULATING PROTEINS, DNA-ENCODING, AND METHOD FOR THEIR USE
ES8103976A1 (es) Un metodo de producir proteinas de interferon humano de for-ma le
PT917571E (pt) Gene relacionado com agouti
DE69839444D1 (de) Smad 6 und dessen anwendungen
DK346385D0 (da) Genetiske sekvenser, hermed kodede interferon-peptider af type i og organismer, der producerer disse
DE69737651D1 (de) Cortistatin: neuropeptide, zusammensetzungen und methoden
DE69728897D1 (de) Saeugetierchemokine
ZA916171B (en) Protein structure of the plant toxin gelonin
ZA978503B (en) Vertebrate smoothened proteins
ES2150937T3 (es) Autotaxina: proteina estimulante de la motilidad util en el diagnostico y terapia del cancer.
BR9713632A (pt) Citocina de mamìfero relacionada com a il-10
PT914417E (pt) Dnase ii humana
ATE275207T1 (de) Dna zur abschätzung des progressionspotentials von zervixläsionen
IT8521507A0 (it) Vettore di clonaggio, molecole di dna ricombinante, ceppi di bacillus subtilis trasformati con dette molecole e metodi per l'espressione di geni eterologhi e produzione e secrezione di proteine codificate da detti geni.
MX9803086A (es) Nuevo adn y proceso para preparar proteina usando el adn.
DE69636737D1 (de) Neues immunoregulatorisches protein lst-1
MX9600765A (es) Proteina y metodos para producir la proteina.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 241446

Country of ref document: ES