ES2070866T3 - Vacunas recombinantes contra la coccidiosis. - Google Patents

Vacunas recombinantes contra la coccidiosis.

Info

Publication number
ES2070866T3
ES2070866T3 ES89110056T ES89110056T ES2070866T3 ES 2070866 T3 ES2070866 T3 ES 2070866T3 ES 89110056 T ES89110056 T ES 89110056T ES 89110056 T ES89110056 T ES 89110056T ES 2070866 T3 ES2070866 T3 ES 2070866T3
Authority
ES
Spain
Prior art keywords
surface antigens
dna
vaccines against
recombinant vaccines
eimeria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89110056T
Other languages
English (en)
Inventor
Werner Altenburger
Mary-Helen Binger
Richard Anthony Chizzonite
Richard Allen Kramer
Peter Thomas Lomedico
Stephen J Mcandrew
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2070866T3 publication Critical patent/ES2070866T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

ESTA INVENCION SE PROPORCIONA SECUENCIAS DE DNA QUE CODIFICAN ANTIGENOS SUPERFICIALES DE EIMERIA, VECTORES RECOMBINANTES QUE CONTIENEN DICHAS SECUENCIAS DE DNA, ORGANISMOS HUESPED TRANSFORMADOS QUE CONTIENEN TALES VECTORES Y METODOS PARA PRODUCIR LOS ANTIGENOS USANDO LOS MICROORGANISMOS TRANSFORMADOS. TAMBIEN SE PROPORCIONAN METODOS PARA LA PROTECCION DE POLLOS FRENTE A LA COCCIDIASIS USANDO LOS ANTIGENOS SUPERFICIALES DE EIMERIA. LOS ANTIGENOS SUPERFICIALES PUEDEN SER ADMINISTRADOS PARA DICHA PROTECCION BIEN COMO PROTEINAS PURIFICADAS O EN FORMA DE DNA QUE CODIFICA LAS PROTEINAS EN UN VECTOR VIRICO ADECUADO TAL COMO VIRUS DE VACCINIA.
ES89110056T 1988-06-03 1989-06-02 Vacunas recombinantes contra la coccidiosis. Expired - Lifetime ES2070866T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20272188A 1988-06-03 1988-06-03

Publications (1)

Publication Number Publication Date
ES2070866T3 true ES2070866T3 (es) 1995-06-16

Family

ID=22750986

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89110056T Expired - Lifetime ES2070866T3 (es) 1988-06-03 1989-06-02 Vacunas recombinantes contra la coccidiosis.

Country Status (22)

Country Link
US (2) US5661015A (es)
EP (1) EP0344808B1 (es)
JP (1) JP3051130B2 (es)
KR (1) KR0156545B1 (es)
CN (3) CN1040126C (es)
AR (1) AR241942A1 (es)
AT (1) ATE120489T1 (es)
AU (1) AU635704B2 (es)
CA (1) CA1340538C (es)
DE (1) DE68921923T2 (es)
DK (1) DK272889A (es)
ES (1) ES2070866T3 (es)
FI (1) FI101453B1 (es)
HU (1) HU212505B (es)
IE (1) IE67544B1 (es)
IL (1) IL90489A0 (es)
MC (1) MC2039A1 (es)
NO (1) NO303876B1 (es)
NZ (1) NZ229377A (es)
PT (1) PT90727B (es)
YU (1) YU47880B (es)
ZA (1) ZA893740B (es)

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US5174993A (en) * 1981-12-24 1992-12-29 Health Research Inc. Recombinant avipox virus and immunological use thereof
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
US5279960A (en) * 1984-07-05 1994-01-18 Enzon Corp. 25 KD coccidial antigen of eimeria tenella
US5824656A (en) * 1988-01-15 1998-10-20 Merck & Co., Inc. Recombinant and native group B eimeria tenella immunogens useful as coccidiosis vaccines
EP0432168B1 (en) * 1988-07-05 1996-10-16 British Technology Group Usa Inc Genetically engineered coccidiosis vaccine
ZA902147B (en) * 1989-03-28 1990-12-28 Akzo Nv Coccidiosis vaccine
DE68909041T2 (de) * 1989-06-21 1994-01-13 Akzo Nv Eimeria tenella-Vakzin.
ZA9010461B (en) * 1990-01-26 1991-10-30 Hoffmann La Roche Recombinant coccidiosis vaccines-5-7 eimeria surface antigen
CA2106093A1 (en) * 1991-03-14 1992-09-15 David E. Harwood Recombinant anticoccidial vaccine
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
WO1996040233A1 (en) 1995-06-07 1996-12-19 Pfizer Inc. In ovo vaccination against coccidiosis
CA2223700C (en) 1995-06-07 2002-05-07 Pfizer Inc. In ovo vaccination against coccidiosis
ES2253746T3 (es) * 1995-07-03 2006-06-01 Akzo Nobel N.V. Vacuna contra la coccidiosis aviar.
AU2590997A (en) * 1996-03-29 1997-10-22 Life Technologies, Inc. Method for increasing viability and transformation efficiency of bacteria during storage at low temperatures
US6632923B1 (en) * 1996-11-27 2003-10-14 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
US6627205B2 (en) 1997-12-01 2003-09-30 Pfizer Incorporated Ovo vaccination against coccidiosis
NZ500033A (en) * 1998-10-07 2001-06-29 Akzo Nobel Nv Hydrophilic eimeria polypeptides for use as coccidiosis vaccines
US6984378B1 (en) 1999-02-26 2006-01-10 Pfizer, Inc. Method for the purification, recovery, and sporulation of cysts and oocysts
ZA200400479B (en) * 2001-07-06 2006-05-31 Abic Biolog Lab Teva Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use
KR20040021678A (ko) 2001-08-30 2004-03-10 엠브렉스, 인코포레이티드 난포낭을 생산하기 위한 개선된 방법
KR100490669B1 (ko) * 2001-08-30 2005-05-19 (주)아비코아생명공학연구소 조류 콕시듐증을 유발하는 에이메리아 종의 포자소체 표면항원에 대한 ｓｃＦｖ 재조합 항체
JP3995541B2 (ja) * 2002-06-28 2007-10-24 株式会社ゲン・コーポレーション 抗鶏コクシジウム症組成物
DE10330235A1 (de) * 2003-07-04 2005-01-20 Bayer Healthcare Ag Neues Eimeria Gen und Protein sowie deren Verwendung
WO2005023866A2 (en) * 2003-09-10 2005-03-17 Baxter International Inc. Peptides that inhibit complement activation
EP1742656B1 (en) * 2004-03-12 2010-06-16 University Of Georgia Research Foundation, Inc. Novel peanut skin extract as a vaccine adjuvant
US7087425B2 (en) * 2004-03-31 2006-08-08 Embrex, Inc. Method of purifying oocysts using enzymatic digestion of fecal debris
US20110078828A1 (en) * 2004-09-10 2011-03-31 Guardian Biotechnologies Inc. Multi epitope vaccine for poultry
EP1666489B1 (en) * 2004-12-01 2007-11-21 Zeon Corporation DNA encoding an antigenic protein of eimeria apical membrane antigen 1 and use thereof
CN100398156C (zh) * 2005-11-23 2008-07-02 南京农业大学 用于预防鸡球虫病的免疫调节型dna疫苗
US20080194006A1 (en) * 2007-02-08 2008-08-14 Embrex, Inc. Methods of releasing sporocysts from oocysts using controlled shear forces
US11701683B2 (en) 2010-12-22 2023-07-18 The Procter & Gamble Company Methods for foil stamping parts having asymmetrical edges
US10758601B2 (en) 2016-12-22 2020-09-01 Intervet Inc. Eimeria vaccine with improved efficacy
CA3142023A1 (en) * 2019-05-28 2020-12-03 Case Western Reserve University Compositions and methods for preserving dna methylation
AU2021281223A1 (en) 2020-05-27 2023-01-05 Case Western Reserve University Compositions and methods for preserving DNA methylation
CN115806990A (zh) * 2022-12-12 2023-03-17 佛山市正典生物技术有限公司 一种表达禽4型腺病毒fiber2蛋白和荧光标签的重组球虫载体及其检测方法

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US4237224A (en) 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
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US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
WO1986000528A1 (en) * 1984-07-05 1986-01-30 Genex Corporation Cloned gene and method for making and using the same
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EP0241139A3 (en) * 1986-03-13 1989-04-19 Merck & Co. Inc. Anti-idiotypic vaccine for coccidiosis
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EP0373168B1 (en) * 1987-03-06 1996-11-13 Amgen Boulder Inc. Polypeptide useful in diagnosis of coccidia infection and recombinant-dna methods for manufacturing same
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NZ227597A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Eimeria tenella group b immunogens and their production
NZ227595A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Recombinant production of eimeria tenella antigens and their use
AU620366B2 (en) * 1988-02-12 1992-02-20 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated response and method of producing the same
DE3926461A1 (de) * 1989-07-15 1991-01-24 Suttner Gmbh & Co Kg Ventilpistole, insbesondere fuer ein hochdruckreinigungsgeraet

Also Published As

Publication number Publication date
CN1186695A (zh) 1998-07-08
DK272889A (da) 1989-12-04
NO892251D0 (no) 1989-06-02
PT90727A (pt) 1989-12-29
FI892714L (fi) 1989-12-04
HUT52963A (en) 1990-09-28
FI101453B (fi) 1998-06-30
KR910000183A (ko) 1991-01-29
EP0344808A1 (en) 1989-12-06
JPH037594A (ja) 1991-01-14
PT90727B (pt) 1994-11-30
CA1340538C (en) 1999-05-11
CN1040126C (zh) 1998-10-07
MC2039A1 (fr) 1990-05-30
DE68921923T2 (de) 1995-08-10
US5661015A (en) 1997-08-26
AU3601689A (en) 1989-12-07
ATE120489T1 (de) 1995-04-15
NZ229377A (en) 1992-06-25
KR0156545B1 (ko) 1998-11-16
NO303876B1 (no) 1998-09-14
AR241942A1 (es) 1993-01-29
CN1038837A (zh) 1990-01-17
CN1187368A (zh) 1998-07-15
AU635704B2 (en) 1993-04-01
YU47880B (sh) 1996-05-20
IE891812L (en) 1989-12-03
ZA893740B (en) 1990-02-28
EP0344808B1 (en) 1995-03-29
HU212505B (en) 1996-07-29
DE68921923D1 (de) 1995-05-04
IE67544B1 (en) 1996-04-17
CN1077438C (zh) 2002-01-09
CN1076204C (zh) 2001-12-19
FI892714A0 (fi) 1989-06-02
US20030175311A1 (en) 2003-09-18
FI101453B1 (fi) 1998-06-30
JP3051130B2 (ja) 2000-06-12
NO892251L (no) 1989-12-04
IL90489A0 (en) 1990-01-18
YU113889A (en) 1991-10-31
DK272889D0 (da) 1989-06-02

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