ES2070902T3 - Complejos de cinc y ceftiofur. - Google Patents

Complejos de cinc y ceftiofur.

Info

Publication number
ES2070902T3
ES2070902T3 ES89300589T ES89300589T ES2070902T3 ES 2070902 T3 ES2070902 T3 ES 2070902T3 ES 89300589 T ES89300589 T ES 89300589T ES 89300589 T ES89300589 T ES 89300589T ES 2070902 T3 ES2070902 T3 ES 2070902T3
Authority
ES
Spain
Prior art keywords
ceftiofur
zinc
complexes
antibiotic
zinc ceftiofur
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89300589T
Other languages
English (en)
Inventor
Alexander R Cazers
K Thomas Koshy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ES2070902T3 publication Critical patent/ES2070902T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

SE HA ENCONTRADO QUE LOS COMPLEJOS DE CLETIOFUR DE CINC, P.E. HIDROCLORURO DE CELTIFUR DE CINC Y COMPLEJOS SODICOS DE CELTIOFUR DE CINC POSEEN LA BUENA ACTIVIDAD ANTIBIOTICA DEL DELTIOFUR MIENTRAN QUE TIENEN UNA VELOCIDAD DE DISOLUCION BAJA Y PROPIEDADES DE VIDA MEDIA LARGA, PERMITIENDO LA FORMULACION DE PREPARADOS DE CELTIOFUR DE LARGA DURACION UTILES EN TERAPIA CON ANTIBIOTICOS DE ANIMALES DE SANGRE CALIENTE. LA INVENCION PROPORCIONA COMPOSICIONES FARMACEUTICAS DE TALES COMPLEJOS DE CELTIOFUR DE CINC Y UN METODO PARA SU EMPLEO EN VETERINARIA.
ES89300589T 1988-02-16 1989-01-23 Complejos de cinc y ceftiofur. Expired - Lifetime ES2070902T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/156,360 US4877782A (en) 1988-02-16 1988-02-16 Zinc ceftiofur complexes

Publications (1)

Publication Number Publication Date
ES2070902T3 true ES2070902T3 (es) 1995-06-16

Family

ID=22559250

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89300589T Expired - Lifetime ES2070902T3 (es) 1988-02-16 1989-01-23 Complejos de cinc y ceftiofur.

Country Status (9)

Country Link
US (1) US4877782A (es)
EP (2) EP0329286B1 (es)
JP (1) JPH03502793A (es)
AT (1) ATE121093T1 (es)
DE (1) DE68922127T2 (es)
DK (1) DK178190A (es)
ES (1) ES2070902T3 (es)
NZ (1) NZ227872A (es)
WO (1) WO1989007600A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611461B2 (en) * 1987-07-29 1991-06-13 Pharmacia & Upjohn Company Controlled release of antibiotic salts from an implant
KR100296810B1 (ko) * 1993-03-12 2001-10-24 로렌스 티. 마이젠헬더 결정성세프티오퍼유리산
US5614551A (en) * 1994-01-24 1997-03-25 The Johns Hopkins University Inhibitors of fatty acid synthesis as antimicrobial agents
US5736151A (en) * 1996-12-09 1998-04-07 Pharmacia & Upjohn Company Antibiotic oil suspensions
JP4319835B2 (ja) * 2000-11-22 2009-08-26 サンド・アクチエンゲゼルシヤフト セフチオフルナトリウム塩の製造方法
KR100423895B1 (ko) * 2001-02-19 2004-03-24 주식회사 엘지생명과학 셉티오퍼 하이드로클로라이드의 현탁제 조성물
US6555679B2 (en) 2001-10-03 2003-04-29 Orchid Chemicals & Pharmaceuticals Ltd. Method for preparation of ceftiofur sodium from its hydrohalide salts
US6555680B1 (en) 2001-12-10 2003-04-29 Orchid Chemicals & Pharmaceuticals Ltd. Method for the preparation of ceftiofur sodium
US6800756B2 (en) * 2002-05-03 2004-10-05 Orchid Chemicals And Pharmaceuticals, Ltd. Method for the preparation of ceftiofur sodium and its intermediates
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
CN109575053A (zh) * 2019-01-14 2019-04-05 天津市中升挑战生物科技有限公司 一种锌配合物及其制备方法
CN109464391A (zh) * 2019-01-14 2019-03-15 天津市中升挑战生物科技有限公司 一种注射液及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356264A (en) * 1980-04-11 1982-10-26 International Minerals & Chemical Corp. Zinc-containing antibiotic agents
FR2479229B1 (fr) * 1980-03-26 1986-01-17 Clin Midy Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives
IT1181672B (it) * 1984-10-25 1987-09-30 Upjohn Co Cefalosporina alogenidrato cristallino
WO1987001117A2 (en) * 1985-08-12 1987-02-26 The Upjohn Company Conversion of cephalosporin hydrohalide salt to alkali metal salt

Also Published As

Publication number Publication date
DK178190D0 (da) 1990-07-26
DE68922127T2 (de) 1995-10-12
JPH03502793A (ja) 1991-06-27
US4877782A (en) 1989-10-31
DK178190A (da) 1990-07-26
ATE121093T1 (de) 1995-04-15
EP0329286A1 (en) 1989-08-23
DE68922127D1 (de) 1995-05-18
WO1989007600A1 (en) 1989-08-24
EP0393150A1 (en) 1990-10-24
EP0329286B1 (en) 1995-04-12
NZ227872A (en) 1991-07-26

Similar Documents

Publication Publication Date Title
IL74497A0 (en) Pharmaceutical compositions and phenyl carbamate derivatives
SE8602723D0 (sv) Thiazoles, their production and pharmaceutical compositions containing them
IL94433A0 (en) Aminophenol derivatives,their preparation and pharmaceutical compositions containing them
MY101791A (en) New benzimidazole derivatives
GR3026218T3 (en) Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid
ES2070902T3 (es) Complejos de cinc y ceftiofur.
IL89840A0 (en) Substituted flavonoid compounds and salts thereof,their preparation and pharmaceutical compositions containing them
HUT51269A (en) Process for producing benzimidazole derivatives and pharmaceutical compositions comprising same
DE3271532D1 (en) Salts of n-substituted-2-pyrrolidone-4-carboxylic acids as humectants
MY100900A (en) Substituted phenylsulfonyloxybenzimidazolecarbamates, processes for their preparation and their use as medicaments.
ES2002083A6 (es) Un metodo para preparar derivados de piroglutamida
IT1227072B (it) Clavulanato di potassio, procedimento per la sua produzione e composizione farmaceutica
GR3002679T3 (en) Dihydropyridinamides, process for their preparation and their use in medicines
IE40957L (en) 4- o-ó,d-glucopyranosyl -6-o-ó,d- xylohexopyranosyl -2-¹deoxystreptamine
ES8707734A1 (es) Procedimiento para la obtencion de cefalosporinas
PT80221A (en) Improved process for preparing benzamide derivatives useful as anticonvulsant agents
ES8600758A1 (es) Procedimiento para preparar derivados de1,3-dioxolanilo
GR3021769T3 (en) N-(isoquinolein-5-yl)-sulfonyl azacycloalkanes, their process of preparation and pharmaceutical compositions containing them
DK0675900T3 (da) Antibiotika GE 37468 A, B og C
IL77009A0 (en) Biphenylyloxy and biphenylylalkoxy aryl acyl urea derivatives,processes for the preparation thereof and pesticidal compositions containing the same
DE3473826D1 (en) N,n-diethyl-5-methyl-2h-1-benzothiopyrano-(4,3,2-cd)-indazole-2-ethanamine, compositions comprising the same and uses therefor
ITMI921855A1 (it) Derivati di catecolammine, processo per la loro preparazione e composizioni farmaceutiche che li contengono
ES8704903A1 (es) Un metodo para preparar 6-cloro-2-metil-1h-2,3,4,5-tetrahidro-3-benzazepen-n-oxido.
MD457G2 (ro) Derivaţi noi de naftiridină, procedeu de preparare a lor, compoziţii farmaceutice care le conţin, utilizarea lor ca medicamente de antireproducere
IL67400A0 (en) 3,7alpha-diazacyclohepta(j,k)fluorene derivatives,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 329286

Country of ref document: ES