IT1227072B - Clavulanato di potassio, procedimento per la sua produzione e composizione farmaceutica - Google Patents
Clavulanato di potassio, procedimento per la sua produzione e composizione farmaceuticaInfo
- Publication number
- IT1227072B IT1227072B IT8847572A IT4757288A IT1227072B IT 1227072 B IT1227072 B IT 1227072B IT 8847572 A IT8847572 A IT 8847572A IT 4757288 A IT4757288 A IT 4757288A IT 1227072 B IT1227072 B IT 1227072B
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- production
- pharmaceutical composition
- potassium clavulanate
- clavulanate
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- ABVRVIZBZKUTMK-JSYANWSFSA-M potassium clavulanate Chemical compound [K+].[O-]C(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 ABVRVIZBZKUTMK-JSYANWSFSA-M 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US878187A | 1987-01-29 | 1987-01-29 | |
| US7494487A | 1987-07-17 | 1987-07-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8847572A0 IT8847572A0 (it) | 1988-06-27 |
| IT1227072B true IT1227072B (it) | 1991-03-14 |
Family
ID=26678616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8847572A IT1227072B (it) | 1987-01-29 | 1988-01-27 | Clavulanato di potassio, procedimento per la sua produzione e composizione farmaceutica |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0277008B1 (it) |
| JP (2) | JP2648321B2 (it) |
| KR (1) | KR960004535B1 (it) |
| AT (1) | AT399154B (it) |
| AU (1) | AU620538B2 (it) |
| BE (1) | BE1000734A3 (it) |
| CA (1) | CA1326486C (it) |
| CH (1) | CH677671A5 (it) |
| DE (1) | DE3853962T2 (it) |
| DK (1) | DK175709B1 (it) |
| ES (2) | ES2074048T3 (it) |
| FR (1) | FR2610196B1 (it) |
| GB (1) | GB2200355B (it) |
| GR (1) | GR1000035B (it) |
| IE (1) | IE880217L (it) |
| IT (1) | IT1227072B (it) |
| LU (1) | LU87123A1 (it) |
| NZ (1) | NZ223316A (it) |
| PT (1) | PT86631B (it) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2435859A (en) * | 1945-06-06 | 1948-02-10 | John E Whitman | Garment hanger |
| US2494711A (en) * | 1946-06-28 | 1950-01-17 | Kusher Hyman | Garment hanger |
| US3474943A (en) * | 1967-02-21 | 1969-10-28 | Frank Mcbain | Skirt hanger |
| SE7805391L (sv) * | 1978-05-11 | 1979-11-12 | Karner & Co Ab | Kledhengare |
| GB9205071D0 (en) * | 1992-03-09 | 1992-04-22 | Wellcome Found | Therapeutic nucleosides |
| AT400033B (de) | 1992-03-10 | 1995-09-25 | Biochemie Gmbh | Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben |
| SE9401169L (sv) * | 1994-04-08 | 1995-10-09 | Corimed Gmbh | Förfarande för framställning av ett antibekteriellt aktivt ämne samt användning därav |
| GB9426261D0 (en) | 1994-12-24 | 1995-02-22 | Spurcourt Ltd | Clavulanic acid salts |
| GB9515809D0 (en) * | 1995-08-02 | 1995-10-04 | Smithkline Beecham Plc | Process |
| AT403375B (de) * | 1995-11-15 | 1998-01-26 | Biochemie Gmbh | Verfahren zur fällung von alkalisalzen der clavulansäure |
| US6414142B1 (en) * | 1996-06-13 | 2002-07-02 | Smithkline Beecham Corporation | Process for preparing potassium clavulanate |
| ATE260096T1 (de) * | 1999-04-01 | 2004-03-15 | Dsm Ip Assets Bv | Agglomerate durch kristallisation |
| BRPI0110774B8 (pt) | 2000-05-13 | 2021-05-25 | Smithkline Beecham Plc | processo para purificação de um sal de ácido clavulânico |
| US20060275219A1 (en) * | 2003-06-10 | 2006-12-07 | Taisho Pharmaceutical Co., Ltd. | Radial spherical crystallization product, process for producing the same, and dry powder preparation containing the crystallization product |
| CN100384853C (zh) * | 2004-05-10 | 2008-04-30 | 河北张药股份有限公司 | 替卡西林钠的合成方法 |
| KR102459377B1 (ko) * | 2022-03-18 | 2022-10-28 | 주식회사 에이치투뉴트리션 | 무알콜 단백질 맥주의 제조방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1508977A (en) * | 1974-04-20 | 1978-04-26 | Beecham Group Ltd | Beta-lactam antibiotic from streptomyces clavuligerus |
| GB1504425A (en) * | 1975-08-20 | 1978-03-22 | Beecham Group Ltd | Salts of clavulanic acid |
| GB2003863B (en) * | 1977-09-01 | 1982-03-31 | Beecham Group Ltd | Chemical process |
| DE3063683D1 (en) * | 1979-08-24 | 1983-07-14 | Beecham Group Plc | Amine salt of clavulanic acid, its preparation and use |
| US4454069A (en) * | 1979-08-24 | 1984-06-12 | Beecham Group Limited | Clavulanic acid salts and their preparation from the tertiary butyl amine salt |
| EP0080862B1 (en) * | 1981-12-02 | 1985-09-25 | Beecham Group Plc | Pharmaceutical formulation comprising beta-lactam antibiotics |
| FR2586561B1 (fr) * | 1985-09-05 | 1988-05-20 | Rhone Poulenc Sante | Procede de preparation d'agglomerats spheriques de paracetamol et produits obtenus |
-
1988
- 1988-01-27 GB GB8801765A patent/GB2200355B/en not_active Expired - Lifetime
- 1988-01-27 IT IT8847572A patent/IT1227072B/it active
- 1988-01-27 PT PT86631A patent/PT86631B/pt unknown
- 1988-01-27 ES ES88300704T patent/ES2074048T3/es not_active Expired - Lifetime
- 1988-01-27 DK DK198800404A patent/DK175709B1/da not_active IP Right Cessation
- 1988-01-27 EP EP88300704A patent/EP0277008B1/en not_active Expired - Lifetime
- 1988-01-27 IE IE880217A patent/IE880217L/xx not_active IP Right Cessation
- 1988-01-27 ES ES8800226A patent/ES2008418A6/es not_active Expired
- 1988-01-27 NZ NZ223316A patent/NZ223316A/xx unknown
- 1988-01-27 GR GR880100031A patent/GR1000035B/el not_active IP Right Cessation
- 1988-01-27 CA CA000557422A patent/CA1326486C/en not_active Expired - Lifetime
- 1988-01-27 DE DE3853962T patent/DE3853962T2/de not_active Expired - Lifetime
- 1988-01-27 AT AT0016388A patent/AT399154B/de not_active IP Right Cessation
- 1988-01-28 BE BE8800098A patent/BE1000734A3/fr not_active IP Right Cessation
- 1988-01-28 AU AU10927/88A patent/AU620538B2/en not_active Expired
- 1988-01-28 KR KR1019880000765A patent/KR960004535B1/ko not_active Expired - Lifetime
- 1988-01-28 CH CH299/88A patent/CH677671A5/de not_active IP Right Cessation
- 1988-01-29 FR FR888801033A patent/FR2610196B1/fr not_active Expired - Lifetime
- 1988-01-29 LU LU87123A patent/LU87123A1/fr unknown
- 1988-01-29 JP JP63021144A patent/JP2648321B2/ja not_active Expired - Lifetime
-
1996
- 1996-12-03 JP JP8339027A patent/JP2716966B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU1092788A (en) | 1988-08-04 |
| BE1000734A3 (fr) | 1989-03-21 |
| LU87123A1 (fr) | 1988-05-03 |
| AT399154B (de) | 1995-03-27 |
| ES2074048T3 (es) | 1995-09-01 |
| DK40488A (da) | 1988-07-30 |
| GB2200355B (en) | 1990-08-01 |
| JP2648321B2 (ja) | 1997-08-27 |
| ES2008418A6 (es) | 1989-07-16 |
| GR1000035B (el) | 1990-03-12 |
| GB8801765D0 (en) | 1988-02-24 |
| GB2200355A (en) | 1988-08-03 |
| FR2610196A1 (fr) | 1988-08-05 |
| DK40488D0 (da) | 1988-01-27 |
| KR890002166A (ko) | 1989-04-08 |
| PT86631B (pt) | 1992-01-31 |
| DE3853962D1 (de) | 1995-07-20 |
| IE880217L (en) | 1988-07-29 |
| NZ223316A (en) | 1989-10-27 |
| EP0277008B1 (en) | 1995-06-14 |
| KR960004535B1 (ko) | 1996-04-06 |
| CH677671A5 (it) | 1991-06-14 |
| EP0277008A1 (en) | 1988-08-03 |
| GR880100031A (en) | 1988-12-16 |
| DK175709B1 (da) | 2005-01-31 |
| AU620538B2 (en) | 1992-02-20 |
| JP2716966B2 (ja) | 1998-02-18 |
| DE3853962T2 (de) | 1996-02-08 |
| JPS63270687A (ja) | 1988-11-08 |
| ATA16388A (de) | 1994-08-15 |
| PT86631A (pt) | 1988-02-01 |
| JPH09169771A (ja) | 1997-06-30 |
| CA1326486C (en) | 1994-01-25 |
| IT8847572A0 (it) | 1988-06-27 |
| FR2610196B1 (fr) | 1991-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19990129 |