ES2070997T3 - Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos. - Google Patents
Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos.Info
- Publication number
- ES2070997T3 ES2070997T3 ES90203076T ES90203076T ES2070997T3 ES 2070997 T3 ES2070997 T3 ES 2070997T3 ES 90203076 T ES90203076 T ES 90203076T ES 90203076 T ES90203076 T ES 90203076T ES 2070997 T3 ES2070997 T3 ES 2070997T3
- Authority
- ES
- Spain
- Prior art keywords
- turkeys
- herpes viruses
- recombinant herpes
- vector vaccines
- vaccines derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
- C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/816—Viral vaccine for avian species, e.g. poultry or other birds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
ESTA INVENCION SE REFIERE A UN VIRUS RECOMBINANTE DEL HERPES DE LOS PAVOS (HVT) QUE CONTIENE UN GEN HETEROLOGO INCORPORADO EN UNA REGION DE INSERCION DEL GENOMA DE HVT. LA INVENCION SE REFIERE TAMBIEN A UNA VACUNA DE VECTOR QUE COMPRENDE UN HVT RECOMBINANTE QUE EXPRESA UN POLIPEPTIDO ANTIGENICO HETEROLOGO E INDUCE UNA ADECUADA RESPUESTA INMUNOLOGICA SOBRE LA INFECCION DE UN ANIMAL RECEPTOR ADECUADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP89203071 | 1989-12-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2070997T3 true ES2070997T3 (es) | 1995-06-16 |
Family
ID=8202517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90203076T Expired - Lifetime ES2070997T3 (es) | 1989-12-04 | 1990-11-21 | Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5187087A (es) |
| EP (1) | EP0431668B1 (es) |
| JP (1) | JP3194751B2 (es) |
| KR (1) | KR0179994B1 (es) |
| CN (1) | CN1056878C (es) |
| AU (1) | AU633663B2 (es) |
| BR (1) | BR1100637A (es) |
| CA (1) | CA2031164C (es) |
| DE (1) | DE69016956T2 (es) |
| ES (1) | ES2070997T3 (es) |
| HU (1) | HU214904B (es) |
| NZ (1) | NZ236294A (es) |
| ZA (1) | ZA909570B (es) |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5961982A (en) * | 1985-09-06 | 1999-10-05 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
| US5928648A (en) * | 1985-09-06 | 1999-07-27 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
| US5965138A (en) * | 1985-09-06 | 1999-10-12 | Syntro Corporation | Recombinant chimeric virus and uses thereof |
| WO1990002803A2 (en) * | 1988-09-13 | 1990-03-22 | Rhone-Merieux S.A. | Viral vaccines |
| FR2693472B1 (fr) * | 1992-06-26 | 1994-12-23 | Rhone Merieux | Mutants du virus de la rhinotrachéite infectieuse bovine, délétés dans l'un des gènes des glycoprotéines mineures, vaccins préparés à partir de ces souches, méthodes de production et méthodes d'utilisation. |
| FR2659349B1 (fr) * | 1990-03-12 | 1993-12-24 | Rhone Merieux | Virus herpes recombinants notamment pour la realisation de vaccins, leur procede de preparation, les plasmides realises au cours de ce procede et les vaccins obtenus. |
| EP0473210B1 (en) * | 1990-07-30 | 1994-04-13 | Akzo Nobel N.V. | Recombinant Marek's disease virus |
| FR2666589B1 (fr) * | 1990-09-07 | 1994-08-05 | Rhone Merieux | Nouveaux virus herpes recombinants, vaccin a base de ces recombinants, leur procede de preparation, genes, vecteurs et plasmides utilises dans ce procede. |
| ZA918426B (en) * | 1990-10-31 | 1992-12-30 | Akzo Nv | Chicken anemia virus vaccine and diagnostic |
| DE4110962A1 (de) * | 1991-04-05 | 1992-10-08 | Bayer Ag | Equine herpesviren (ehv), die fremd-dna enthalten, verfahren zu ihrer herstellung und ihre verwendung in impfstoffen |
| AU657144B2 (en) * | 1991-07-09 | 1995-03-02 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Recombinant Marek's disease virus, process for preparing the same and vaccine containing the same |
| US5853733A (en) * | 1993-02-26 | 1998-12-29 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
| US6913751B2 (en) | 1992-06-12 | 2005-07-05 | Schering-Plough Veterinary Corporation | Recombinant avian herpesvirus useful in vaccine production |
| JP3529134B2 (ja) | 1992-07-30 | 2004-05-24 | アクゾ・ノベル・エヌ・ベー | 組換えネコヘルペスウイルスのベクターワクチン |
| US5403582A (en) * | 1993-01-21 | 1995-04-04 | Nippon Zeon Co., Ltd. | Vaccine comprising fowlpox virus recombinants expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus |
| EP0609739A1 (en) * | 1993-02-02 | 1994-08-10 | American Cyanamid Company | Method of reversing immunosuppression in vaccines |
| US6875856B2 (en) | 1993-09-24 | 2005-04-05 | Syntro Corporation | Recombinant infectious laryngotracheitis virus and uses thereof |
| EP0745127A4 (en) * | 1994-01-11 | 1999-10-20 | Cornell Res Foundation Inc | CONTROLLING MARE'S DISEASE BY PREVENTING LATENCY AND DEVELOPING TUMOR CELLS |
| WO1995021255A1 (en) * | 1994-02-07 | 1995-08-10 | Cornell Research Foundation, Inc. | Compositions useful in controlling marek's disease |
| FR2719056B1 (fr) * | 1994-04-20 | 1996-09-06 | Rhone Merieux | Herpesvirus transformés pour exprimer gD in vitro. |
| US5833980A (en) * | 1995-10-27 | 1998-11-10 | Board Of Trustess Operating Michigan State University | Sustainable cell line for the production of the Marek's disease vaccines |
| US6048535A (en) | 1997-06-12 | 2000-04-11 | Regents Of The University Of Minnesota | Multivalent in ovo avian vaccine |
| WO1999018215A1 (en) * | 1997-10-03 | 1999-04-15 | Nippon Zeon Co., Ltd. | Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same |
| WO1999043839A1 (en) | 1998-02-27 | 1999-09-02 | The Trustees Of The University Of Pennsylvania | Vaccines, immunotherapeutics and methods for using the same |
| CN1120238C (zh) * | 1998-05-04 | 2003-09-03 | 本元正阳基因技术股份有限公司 | 以粘粒为基础构建重组单纯疱疹病毒及其用途 |
| EP1038952A3 (en) | 1998-12-09 | 2001-06-27 | Pfizer Products Inc. | Processes for preparation of Marek's Disease Virus using continuous avian cell lines |
| KR20010103788A (ko) | 1999-03-03 | 2001-11-23 | 멕코나시 에블린 에이치. | 백신 및 유전자요법 조성물 및 이들의 제조 및 사용방법 |
| AU779395B2 (en) | 1999-04-30 | 2005-01-20 | Institut De Recherche Cliniques De Montreal (Ircm) | Mutant human CD80 and compositions for and methods of making and using the same |
| AU6698900A (en) * | 1999-07-16 | 2001-02-05 | Agricultural Research Service | Live recombinant vaccine against avian leukosis virus using a marek's disease virus (mdv) virus as vector |
| DK1301637T3 (da) * | 2000-07-14 | 2008-09-29 | Univ Pennsylvania | DNA-vacciner, der koder for HIV accessoriske proteiner |
| AU2002211490A1 (en) * | 2000-10-04 | 2002-04-15 | The Trustees Of The University Of Pennsylvania | Compositions and methods of using capsid protein from flaviviruses and pestiviruses |
| AR031405A1 (es) * | 2000-11-21 | 2003-09-24 | Wyeth Corp | Metodos y vacunas para conferir proteccion in ovo contra la rinotraqueitis del pavo |
| US7314715B2 (en) | 2001-06-14 | 2008-01-01 | Schering-Plough Animal Health Corporation | Recombinant avian herpesvirus useful in vaccine production |
| NZ570709A (en) | 2003-06-13 | 2010-04-30 | Univ Pennsylvania | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
| AU2004249191B2 (en) | 2003-06-13 | 2011-01-06 | The Trustees Of The University Of Pennsylvania | Vaccines, immunotherapeutics and methods for using the same |
| WO2007050095A2 (en) | 2004-11-19 | 2007-05-03 | The Trustees Of The University Of Pennsylvania | Improved vaccines and methods for using the same |
| ATE533782T1 (de) * | 2006-01-13 | 2011-12-15 | Univ Pennsylvania | Impfstoffe und immuntherapeutika mit codon- optimiertem il-15 und verwendungsverfahren dafür |
| US9259463B2 (en) | 2006-01-16 | 2016-02-16 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Chlamydia vaccine |
| KR102511874B1 (ko) | 2006-07-28 | 2023-03-20 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 개선된 백신 및 이의 사용 방법 |
| EP2274442B1 (en) * | 2008-04-04 | 2016-06-29 | The Trustees Of The University Of Pennsylvania | Consensus sequences of chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same |
| EP2265715B1 (en) | 2008-04-04 | 2016-12-28 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using il-28 and compositions and methods of using the same |
| EP2291397A1 (en) * | 2008-06-23 | 2011-03-09 | Intervet International BV | Recombinant herpesvirus of turkeys encoding for interleukin-12 |
| JP5753090B2 (ja) | 2008-10-29 | 2015-07-22 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 改良型hcvワクチンおよびその使用方法 |
| US8921536B2 (en) | 2008-10-29 | 2014-12-30 | The Trustees Of The University Of Pennsylvania | HCV vaccines and methods for using the same |
| CA2653478A1 (en) * | 2009-01-23 | 2010-07-23 | Gregg Martin | Automated wash system for industrial vehicles |
| US9050287B2 (en) | 2009-01-23 | 2015-06-09 | The Trustees Of The University Of Pennsylvania | Vaccines for human papilloma virus and methods for using the same |
| KR20120093163A (ko) | 2009-09-14 | 2012-08-22 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | Il-15 수용체 알파 및/또는 이를 인코딩하는 핵산 분자를 포함하는 백신 및 면역 치료제, 및 이를 이용하는 방법 |
| BR112012010357B1 (pt) | 2009-11-02 | 2022-05-24 | Inovio Pharmaceuticals, Inc. | Proteínas de consenso de vírus de doença de febre aftosa (fmdv), sequências de codificação para as mesmas e vacinas feitas a partir das mesmas |
| US8298820B2 (en) | 2010-01-26 | 2012-10-30 | The Trustees Of The University Of Pennsylvania | Influenza nucleic acid molecules and vaccines made therefrom |
| WO2011097640A1 (en) | 2010-02-08 | 2011-08-11 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same |
| CN103370079B (zh) | 2010-10-18 | 2016-08-10 | 英特维特国际股份有限公司 | 针对家禽中禽流感的火鸡疱疹病毒作为载体的疫苗 |
| WO2012065164A2 (en) | 2010-11-12 | 2012-05-18 | The Trustees Of The University Of Pennsylvania | Consensus prostate antigens nucleic acid molecule encoding the same and vaccine and uses comprising the same |
| CA2826199A1 (en) | 2011-01-31 | 2012-08-09 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof |
| US9238679B2 (en) | 2011-02-11 | 2016-01-19 | The Trustees Of The University Of Pennslyvania | Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same |
| US9403879B2 (en) | 2011-02-11 | 2016-08-02 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecule encoding hepatitis B virus core protein and vaccine comprising the same |
| EP2681232A1 (en) * | 2011-03-02 | 2014-01-08 | Intervet International B.V. | Infectious bronchitis virus (ibv) spike protein as subunit vaccine |
| KR102314421B1 (ko) | 2011-07-11 | 2021-10-19 | 이노비오 파마수티컬즈, 인크. | 교차-보호성 아레나바이러스 백신 및 이의 사용 방법 |
| KR102373828B1 (ko) | 2011-10-12 | 2022-03-14 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 인간 파필로마 바이러스에 대한 백신 및 이것을 사용하는 방법 |
| IN2014CN02681A (es) * | 2011-10-21 | 2015-07-03 | Intervet Int Bv | |
| WO2013057235A1 (en) | 2011-10-21 | 2013-04-25 | Intervet International B.V. | Recombinant nonpathogenic mdv vector providing multivalent immunity |
| KR20140084236A (ko) | 2011-10-24 | 2014-07-04 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 개선된 hcv 백신 및 이것을 사용하는 방법 |
| HRP20190525T4 (hr) | 2011-11-30 | 2023-01-20 | Boehringer Ingelheim Animal Health USA Inc. | Rekombinantni vektori gallid herpesvirusa 3 (mdv serotip 2) koji eksprimiraju antigene ptičjih patogena i njihove uporabe |
| US9101598B2 (en) | 2011-11-30 | 2015-08-11 | Merial, Inc. | Recombinant Gallid herpesvirus 3 (MDV serotype 2) vectors expressing antigens of avian pathogens and uses thereof |
| US9114108B2 (en) | 2011-11-30 | 2015-08-25 | Merial, Inc. | Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof |
| CN104245719B (zh) | 2011-12-12 | 2016-09-14 | 宾夕法尼亚大学托管会 | 包含改进的il-12基因构建体的组合物和疫苗、免疫治疗剂及其使用方法 |
| US9750795B2 (en) | 2011-12-12 | 2017-09-05 | The Trustees Of The University Of Pennsylvania | Proteins comprising MRSA PBP2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat MRSA infections |
| EP2644702A1 (en) | 2012-03-30 | 2013-10-02 | Ceva Sante Animale | Multivalent recombinant avian herpes virus and vaccine for immunizing avian species |
| WO2013155205A1 (en) | 2012-04-10 | 2013-10-17 | The Trustees Of The University Of Pennsylvania | Human respiratory syncytial virus concensus antigens, nucleic acid constructs and vaccines made thereform, and methods of using same |
| WO2014165291A1 (en) | 2013-03-12 | 2014-10-09 | The Trustees Of The University Of Pennsylvania | Improved vaccines for human papilloma virus and methods for using the same |
| MX428954B (es) | 2013-03-15 | 2025-11-13 | Univ Pennsylvania | Vacunación mejorada contra la hormona liberadora de la hormona de crecimiento (ghrh) humana. |
| WO2014145951A2 (en) | 2013-03-15 | 2014-09-18 | The Trustees Of The University Of Pennsylvania | Foot and mouth disease virus (fmdv) consensus proteins, coding sequences therefor and vaccines made therefrom |
| CN104046597A (zh) * | 2014-06-05 | 2014-09-17 | 北京市农林科学院 | 表达鹦鹉热衣原体pmpD-N基因的HVT重组体及其构建 |
| AR103245A1 (es) | 2014-12-24 | 2017-04-26 | Intervet Int Bv | Vacuna vectorial basada en hvt (herpes virus de los pavos) frente a nd (enfermedad de newcastle) - ibd (enfermedad de gumboro) mejorada |
| CN109310750B (zh) | 2016-06-17 | 2022-08-12 | 英特维特国际股份有限公司 | 编码传染性喉气管炎病毒和传染性法氏囊病病毒抗原的重组非致病性马立克氏病病毒构建体 |
| RU2752836C2 (ru) | 2016-12-14 | 2021-08-09 | БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. | Рекомбинантные hvt-векторы, экспрессирующие множественные антигены патогенов птиц, и содержащие их вакцины |
| CN111542599A (zh) | 2017-10-12 | 2020-08-14 | 英特维特国际股份有限公司 | 编码多种异源抗原的重组非致病性马尔克氏病病毒构建体 |
| CN111479583A (zh) | 2017-12-13 | 2020-07-31 | 艾诺奥医药品有限公司 | 靶向存活素的癌症疫苗和其用途 |
| JP2021506255A (ja) | 2017-12-13 | 2021-02-22 | イノビオ ファーマシューティカルズ,インコーポレイティド | Prameを標的とするがんワクチンおよびその使用 |
| CA3084135C (en) | 2017-12-13 | 2024-03-05 | Inovio Pharmaceuticals, Inc. | Cancer vaccines targeting muc16 and uses thereof |
| CN111479590A (zh) | 2017-12-13 | 2020-07-31 | 艾诺奥医药品有限公司 | 靶向间皮素的癌症疫苗及其使用 |
| RU2759681C1 (ru) | 2017-12-13 | 2021-11-16 | Иновио Фармасьютикалз, Инк. | Противораковые вакцины, нацеленные на boris, и способы их применения |
| CN114616325A (zh) * | 2019-09-11 | 2022-06-10 | 硕腾服务有限责任公司 | 表达禽病原体抗原的重组火鸡疱疹病毒载体和其用途 |
| WO2021123104A1 (en) | 2019-12-20 | 2021-06-24 | Intervet International B.V. | Multivalent hvt vector vaccine |
| US20240252624A1 (en) | 2020-06-17 | 2024-08-01 | Teshome Mebatsion | Recombinant hvt vectors expressing influenza hemagglutinin and immunogenic compositions, and production and uses thereof |
| KR102432779B1 (ko) | 2020-10-07 | 2022-08-16 | 서울과학기술대학교 산학협력단 | 일원화된 흑색 산화물 입자 합성 방법 |
| MX2023007634A (es) | 2020-12-24 | 2023-07-14 | Intervet Int Bv | Vacuna de vector hvt multivalente. |
| JP2025515050A (ja) | 2022-05-05 | 2025-05-13 | インターベット インターナショナル ベー. フェー. | 新規多価hvtベクターワクチン |
| TW202528544A (zh) | 2023-08-25 | 2025-07-16 | 德商百靈佳殷格翰維美迪加股份有限公司 | Hvt aiv載體及其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4859587A (en) * | 1984-06-04 | 1989-08-22 | Institut Merieux | Recombinant herpes simplex viruses, vaccines and methods |
| DE3853819T2 (de) * | 1987-03-19 | 1995-09-21 | Synergen Inc | Virales vektorsystem zum einführen fremder dns-expressionserzeugnisse in gallinaceenvögeln. |
| DE3854190T2 (de) * | 1987-07-27 | 1996-03-28 | Syntro Corp | Attenuierte herpesviren, herpesviren, die für eine aminosäuresequenz kodierende fremde dns beeinhalten und sie enthaltende impfstoffe. |
| JP2779447B2 (ja) * | 1988-03-20 | 1998-07-23 | 財団法人阪大微生物病研究会 | 弱毒マレック病ウイルス・ベクターを用いる組換え遺伝子作成法、及び該ウイルスの組換え体 |
-
1990
- 1990-11-21 ES ES90203076T patent/ES2070997T3/es not_active Expired - Lifetime
- 1990-11-21 DE DE69016956T patent/DE69016956T2/de not_active Expired - Lifetime
- 1990-11-21 EP EP90203076A patent/EP0431668B1/en not_active Expired - Lifetime
- 1990-11-28 ZA ZA909570A patent/ZA909570B/xx unknown
- 1990-11-29 CA CA002031164A patent/CA2031164C/en not_active Expired - Lifetime
- 1990-11-30 US US07/621,193 patent/US5187087A/en not_active Expired - Lifetime
- 1990-11-30 NZ NZ236294A patent/NZ236294A/en unknown
- 1990-12-03 HU HU908031A patent/HU214904B/hu unknown
- 1990-12-03 AU AU67698/90A patent/AU633663B2/en not_active Expired
- 1990-12-03 CN CN90110319A patent/CN1056878C/zh not_active Expired - Lifetime
- 1990-12-04 JP JP41928690A patent/JP3194751B2/ja not_active Expired - Lifetime
- 1990-12-04 KR KR1019900019817A patent/KR0179994B1/ko not_active Expired - Lifetime
-
1993
- 1993-02-16 US US08/018,489 patent/US5470734A/en not_active Expired - Lifetime
-
1997
- 1997-05-13 BR BR1100637A patent/BR1100637A/pt active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP0431668B1 (en) | 1995-02-15 |
| JPH05103667A (ja) | 1993-04-27 |
| CA2031164C (en) | 2001-10-16 |
| US5187087A (en) | 1993-02-16 |
| CN1052896A (zh) | 1991-07-10 |
| US5470734A (en) | 1995-11-28 |
| NZ236294A (en) | 1992-05-26 |
| DE69016956D1 (de) | 1995-03-23 |
| ZA909570B (en) | 1991-10-30 |
| CA2031164A1 (en) | 1991-06-05 |
| DE69016956T2 (de) | 1995-07-20 |
| AU6769890A (en) | 1991-06-06 |
| CN1056878C (zh) | 2000-09-27 |
| AU633663B2 (en) | 1993-02-04 |
| BR1100637A (pt) | 2000-03-21 |
| KR0179994B1 (ko) | 1999-04-01 |
| JP3194751B2 (ja) | 2001-08-06 |
| HU908031D0 (en) | 1991-06-28 |
| HUT57264A (en) | 1991-11-28 |
| EP0431668A1 (en) | 1991-06-12 |
| HU214904B (hu) | 1998-07-28 |
| KR910012233A (ko) | 1991-08-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69632235D1 (de) | Newcastle-Krankheitsvirus-Kombinationsimpfstoff | |
| CA2031164A1 (en) | Recombinant herpesvirus of turkeys and live vector vaccines derived thereof | |
| CY1110359T1 (el) | Εμβολια με βαση σιρκοϊους χοιρων | |
| EA199800638A1 (ru) | Смесь рекомбинантных векторов вируса коровьей оспы в качестве полиоболоченных вирусных вакцин против вируса иммунного дефицита человека | |
| ATE295895T1 (de) | Genetischer impfstoff gegen den immunschwäche virus | |
| HU9401056D0 (en) | Porcine reproductive respiratory syndrome vaccine and diagnostic | |
| ES2001752A6 (es) | Procedimiento para producir una vacuna de herpesvirus, y para produciruna vacuna multivalente. | |
| HUP9802819A2 (hu) | Hősokkfehérje-alapú oltóanyagok és immunterápiák | |
| PT101052A (pt) | Proteinas hibridas uteis na preparacao de vacinas | |
| LU91592I2 (fr) | Combinaison d'anatoxine diphtérique, d'anatoxine tétanique, d'anatoxine coquelucheuse, d'hémagglutinine filamenteuse, de pertactine, d'antigène de surface recombinant du virus de l'hépatite B (protéine S) et de virus poliomyélitique inactivé type 1, type2 et type 3 (Infanrix Penta) | |
| IL130075A0 (en) | A vaccine for eliciting an immune response to an antigen in an animal | |
| PE97298A1 (es) | Composicion para vacunas | |
| DK0838222T3 (da) | Vaccinesammensætninger, der omfatter inaktiverede immunogener og levende kyllingeanæmi-virus (CAV) | |
| MXPA94008605A (es) | Replicacion de un virus no patogenico que expresalas glicoproteinas de la envoltura del virus de ladiarrea viral bovina (bvdv). | |
| ES2061603T3 (es) | Mutantes viricos de la rinotraqueitis bovina infecciosa, vacunas que los contienen, metodos para la produccion de los mismos y metodos para el empleo de los mismos. | |
| ES2053477T3 (es) | Vacuna viva para enfermedades contagiosas de pollos. | |
| ES2144400T3 (es) | Gen que codifica la gliproteina d del virus del herpes equino de tipo 1, su producto genico, anticuerpos y su utilizacion. | |
| ES2188589T3 (es) | Vacuna recombinante del herpes virus felino. | |
| OA09037A (en) | Prevention and treatement of retroviral disease. | |
| ATE317439T1 (de) | Virale vakzine | |
| ES8404188A1 (es) | Procedimiento para proteger anfitriones susceptibles de infeccion de hepatitis. | |
| CA2196416A1 (en) | Recombinant herpes virus with gb gene promoter | |
| DK0606452T3 (da) | Vektorvacciner fra rekombinant katteherpesvirus | |
| DZ1550A1 (fr) | Vaccin depourvu de cellules contre le virus de la maladie marek. | |
| ES2116306T3 (es) | Vacuna a base de virus del herpes bovino modificado tipo 1. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 431668 Country of ref document: ES |