ES2071343T3 - Nuevos peptidos con actividad anticoagulatoria. - Google Patents

Nuevos peptidos con actividad anticoagulatoria.

Info

Publication number
ES2071343T3
ES2071343T3 ES91920137T ES91920137T ES2071343T3 ES 2071343 T3 ES2071343 T3 ES 2071343T3 ES 91920137 T ES91920137 T ES 91920137T ES 91920137 T ES91920137 T ES 91920137T ES 2071343 T3 ES2071343 T3 ES 2071343T3
Authority
ES
Spain
Prior art keywords
pct
new peptides
peptides
anticoagulatory activity
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91920137T
Other languages
English (en)
Inventor
Bernhard Schmied
Hans Wolfgang Hoeffken
Wilfried Hornberger
Harald Bernard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2071343T3 publication Critical patent/ES2071343T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE DESCRIBE UN PEPTIDO DE FORMULA (I) ASI COMO SU PRODUCCION. EL PEPTIDO ES APROPIADO PARA EL TRATAMIENTO DE ENFERMEDADES. TENIENDO X, A1, A7, Y Y W UN SIGNIFICADO DESCRITO EN LA PATENTE.
ES91920137T 1991-02-07 1991-11-21 Nuevos peptidos con actividad anticoagulatoria. Expired - Lifetime ES2071343T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4103649A DE4103649A1 (de) 1991-02-07 1991-02-07 Neue antikoagulatorisch wirksame peptide

Publications (1)

Publication Number Publication Date
ES2071343T3 true ES2071343T3 (es) 1995-06-16

Family

ID=6424532

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91920137T Expired - Lifetime ES2071343T3 (es) 1991-02-07 1991-11-21 Nuevos peptidos con actividad anticoagulatoria.

Country Status (10)

Country Link
US (1) US5393873A (es)
EP (1) EP0570375B1 (es)
JP (1) JP3315690B2 (es)
AT (1) ATE121422T1 (es)
CA (1) CA2099497C (es)
DE (2) DE4103649A1 (es)
DK (1) DK0570375T3 (es)
ES (1) ES2071343T3 (es)
MX (1) MX9203516A (es)
WO (1) WO1992013879A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2776023A1 (en) * 2001-01-12 2002-07-18 Fumapharm Ag Fumaric acid amides
EP1425296B1 (de) * 2001-09-10 2011-04-13 Novel Science International GmbH Organische verbindungen mit biologischer wirkung als thrombinhemmer und ihre verwendung
ATE480561T1 (de) 2004-10-19 2010-09-15 Lonza Ag Verfahren zur festphasen-peptidsynthese
CN101033249B (zh) * 2006-03-10 2011-05-11 周逸明 固相多肽合成比筏芦定的制备方法
US8784896B2 (en) 2012-09-17 2014-07-22 Biopep Solutions, Inc Antioxidant therapy with a whole, leech saliva extract
CN103408459B (zh) * 2013-08-21 2014-10-08 中国药科大学 4-氰基苯丙氨酸的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
CA1328540C (en) * 1987-05-21 1994-04-12 John L. Krstenansky Cyclic anticoagulant peptides
JPH04500802A (ja) * 1988-09-29 1992-02-13 バイオジェン インコーポレイテッド ヒルジンペプチド
FI904329A0 (fi) * 1988-12-05 1990-09-03 Biogen Inc Foerfaranden och kompositioner foer inhibering av tronbocytaggregation.
ZA899247B (en) * 1988-12-07 1990-09-26 Merrell Dow Pharma Anticoagulant peptides
EP0483261A1 (en) * 1989-07-20 1992-05-06 Biogen, Inc. Hirudin peptide derivatives
AU641215B2 (en) * 1990-02-13 1993-09-16 Merrell Dow Pharmaceuticals Inc. Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin
DE4005591A1 (de) * 1990-02-22 1991-09-05 Behringwerke Ag Die blutgerinnung inhibierende peptide, verfahren zu ihrer herstellung und ihre verwendung

Also Published As

Publication number Publication date
WO1992013879A1 (de) 1992-08-20
US5393873A (en) 1995-02-28
EP0570375B1 (de) 1995-04-19
CA2099497A1 (en) 1992-08-08
MX9203516A (es) 1992-08-31
ATE121422T1 (de) 1995-05-15
JPH06504989A (ja) 1994-06-09
JP3315690B2 (ja) 2002-08-19
DK0570375T3 (da) 1995-07-03
DE4103649A1 (de) 1992-08-13
DE59105281D1 (de) 1995-05-24
CA2099497C (en) 2001-12-25
EP0570375A1 (de) 1993-11-24

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