ES2072386T3 - Derivados del penciclovir para el tratamiento de las infecciones de hepatitis-b. - Google Patents

Derivados del penciclovir para el tratamiento de las infecciones de hepatitis-b.

Info

Publication number
ES2072386T3
ES2072386T3 ES90302186T ES90302186T ES2072386T3 ES 2072386 T3 ES2072386 T3 ES 2072386T3 ES 90302186 T ES90302186 T ES 90302186T ES 90302186 T ES90302186 T ES 90302186T ES 2072386 T3 ES2072386 T3 ES 2072386T3
Authority
ES
Spain
Prior art keywords
hepatitis
treatment
penciclovir
infections
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90302186T
Other languages
English (en)
Inventor
Malcolm Richard Boyd
David Sutton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10652653&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2072386(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of ES2072386T3 publication Critical patent/ES2072386T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

EL USO FARMACEUTICO DEL COMPUESTO DE FORMULA (I) O UNA PRO-DROGA O SAL FARMACEUTICAMENTE ACEPTABLE, ESTER DE FOSFATO Y/O DERIVADO DE ACIL EN EL TRATAMIENTO DE HEPATITIS-B, ES DISPUESTO
ES90302186T 1989-03-03 1990-03-01 Derivados del penciclovir para el tratamiento de las infecciones de hepatitis-b. Expired - Lifetime ES2072386T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898904855A GB8904855D0 (en) 1989-03-03 1989-03-03 Pharmaceutical treatment

Publications (1)

Publication Number Publication Date
ES2072386T3 true ES2072386T3 (es) 1995-07-16

Family

ID=10652653

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90302186T Expired - Lifetime ES2072386T3 (es) 1989-03-03 1990-03-01 Derivados del penciclovir para el tratamiento de las infecciones de hepatitis-b.

Country Status (18)

Country Link
US (1) US6136813A (es)
EP (1) EP0388049B1 (es)
JP (1) JP2513519B2 (es)
KR (1) KR0143410B1 (es)
AT (1) ATE122562T1 (es)
AU (1) AU628137B2 (es)
CA (1) CA2011238C (es)
CY (1) CY1870A (es)
DE (1) DE69019404T2 (es)
DK (1) DK0388049T3 (es)
ES (1) ES2072386T3 (es)
GB (1) GB8904855D0 (es)
HK (1) HK116795A (es)
HU (1) HU205715B (es)
IE (1) IE67125B1 (es)
IL (1) IL93594A (es)
LV (1) LV10923B (es)
ZA (1) ZA901572B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9326177D0 (en) * 1993-12-22 1994-02-23 Smithkline Beecham Plc Pharmaceuticals
US6124304A (en) * 1993-10-05 2000-09-26 Smithkline Beecham Plc Penciclovir for the treatment of zoster associated pain
WO1995022330A1 (en) * 1994-02-17 1995-08-24 Commonwealth Scientific And Industrial Research Organisation Antiviral agents
WO1996033720A1 (en) * 1995-04-24 1996-10-31 Smithkline Beecham Plc Use of (r)-penciclovir triphosphate for the manufacture of a medicament for the treatment of viral diseases
WO1998023285A1 (en) * 1996-11-29 1998-06-04 Smithkline Beecham Plc Use of a combination of penciclovir and alpha-interferon in the manufacture of a medicament for the treatment of hepatitis b
US5939423A (en) * 1997-04-16 1999-08-17 Sciclone Pharmaceuticals, Inc. Treatment of hepatitis B infection with thymosin alpha 1 and famciclovir
AUPO912997A0 (en) * 1997-09-11 1997-10-02 Commonwealth Scientific And Industrial Research Organisation Antiviral agents
US6288033B1 (en) 1998-09-25 2001-09-11 Sciclone Pharmaceuticals, Inc. Treatment of hepatitis B infection with thymosin alpha 1 in combination with lamivudine or in combination with lamivudine and famciclovir
IL142910A0 (en) * 1998-11-02 2002-04-21 Triangle Pharmaceuticals Inc Combination therapy to treat hepatitis b virus
AU2013257951A1 (en) 2012-05-11 2015-01-22 Akron Molecules Ag Use of compounds for the treatment of pain

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4230708A (en) * 1977-10-20 1980-10-28 Stichting Rega V.Z.W. Therapeutic application of (S) -or (RS)-9-(2, 3-dihydroxypropyl) adenine for use as antiviral agents
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
US4556659A (en) * 1982-08-09 1985-12-03 Syntex (U.S.A.) Inc. Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents
US4649140A (en) * 1982-10-14 1987-03-10 Burroughs Wellcome Co. Purine derivatives
US5059604A (en) * 1982-10-14 1991-10-22 Burroughs Wellcome Co. 2-amino purine derivatives
EP0141927B1 (en) * 1983-08-18 1991-10-30 Beecham Group Plc Antiviral guanine derivatives
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
EP0216459B1 (en) * 1985-07-27 1990-05-16 Beecham Group Plc 9-substituted guanine monohydrates
SE8602981D0 (sv) * 1986-07-04 1986-07-04 Astra Laekemedel Ab Novel medicinal use
HU196038B (en) * 1987-08-07 1988-09-28 Mta Koezponti Kemiai Kutato In Process for producing antiherpetic pharmaceutics for external use, containing 5-isopropyl-2'-beta-deoxy-uridine
SE8801729D0 (sv) * 1988-05-06 1988-05-06 Astra Ab Purine derivatives for use in therapy
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds

Also Published As

Publication number Publication date
IL93594A0 (en) 1990-12-23
AU5060090A (en) 1990-11-01
IE67125B1 (en) 1996-03-06
IE900733L (en) 1990-09-03
ZA901572B (en) 1991-03-27
LV10923B (en) 1996-06-20
HK116795A (en) 1995-07-21
EP0388049A3 (en) 1991-11-06
EP0388049B1 (en) 1995-05-17
EP0388049A2 (en) 1990-09-19
KR900014385A (ko) 1990-10-23
JP2513519B2 (ja) 1996-07-03
HU205715B (en) 1992-06-29
HU901252D0 (en) 1990-05-28
CY1870A (en) 1996-04-05
LV10923A (lv) 1995-12-20
ATE122562T1 (de) 1995-06-15
US6136813A (en) 2000-10-24
DK0388049T3 (da) 1995-06-06
GB8904855D0 (en) 1989-04-12
JPH02275821A (ja) 1990-11-09
IL93594A (en) 1995-05-26
HUT53522A (en) 1990-11-28
DE69019404D1 (de) 1995-06-22
KR0143410B1 (ko) 1998-07-15
CA2011238C (en) 2000-03-28
AU628137B2 (en) 1992-09-10
DE69019404T2 (de) 1995-10-12
CA2011238A1 (en) 1990-09-03

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