ES2073701T3 - Comprimido de liberacion prolongada a base de 5-mononitrato de isosorbido y su procedimiento de preparacion. - Google Patents

Comprimido de liberacion prolongada a base de 5-mononitrato de isosorbido y su procedimiento de preparacion.

Info

Publication number
ES2073701T3
ES2073701T3 ES91402377T ES91402377T ES2073701T3 ES 2073701 T3 ES2073701 T3 ES 2073701T3 ES 91402377 T ES91402377 T ES 91402377T ES 91402377 T ES91402377 T ES 91402377T ES 2073701 T3 ES2073701 T3 ES 2073701T3
Authority
ES
Spain
Prior art keywords
mononitrate
isosorbide
release tablet
preparation procedure
prolonged release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91402377T
Other languages
English (en)
Inventor
Joel Bougaret
Michel Sournac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Application granted granted Critical
Publication of ES2073701T3 publication Critical patent/ES2073701T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN COMPRIMIDO DE LIBERACION PROLONGADA, CARACTERIZADO EN QUE COMPRENDE COMO PRINCIPIO ACTIVO EL 5-MONONITRATO DE ISOSORBIDA (5-MNIS) EN FORMA DE UN POLVO QUE PRESENTA UNA GRANULOMETRIA DE 80 (MU)M A 500 (MU)M, EN DISPERSION HOMOGENEA EN UNA MATRIZ HIDROFILA A BASE DE AL MENOS UN COMPONENTE INFLANTE Y DE AL MENOS UN COMPONENTE DILUYENTE. TAMBIEN SE REFIERE AL PROCESO DE PREPARACION DE DICHO COMPUESTO.
ES91402377T 1990-09-07 1991-09-05 Comprimido de liberacion prolongada a base de 5-mononitrato de isosorbido y su procedimiento de preparacion. Expired - Lifetime ES2073701T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9011133A FR2666506A1 (fr) 1990-09-07 1990-09-07 Comprime a liberation prolongee a base de 5-mononitrate d'isosorbide et son procede de preparation.

Publications (1)

Publication Number Publication Date
ES2073701T3 true ES2073701T3 (es) 1995-08-16

Family

ID=9400168

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91402377T Expired - Lifetime ES2073701T3 (es) 1990-09-07 1991-09-05 Comprimido de liberacion prolongada a base de 5-mononitrato de isosorbido y su procedimiento de preparacion.

Country Status (6)

Country Link
US (1) US5334393A (es)
EP (1) EP0477061B1 (es)
AT (1) ATE121936T1 (es)
DE (1) DE69109419T2 (es)
ES (1) ES2073701T3 (es)
FR (1) FR2666506A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK103393D0 (da) * 1993-09-15 1993-09-15 Ferrosan As Praeparat
BE1009380A3 (nl) * 1995-03-14 1997-03-04 Universiteit Gent Lab Voor Far Stabiliserend samenstelling voor suspensie.
AU735799C (en) * 1997-02-28 2005-04-28 Regents Of The University Of California, The Methods and compositions for optimisation of oxygen transport by cell-free systems
US5851555A (en) * 1997-08-15 1998-12-22 Fuisz Technologies Ltd. Controlled release dosage forms containing water soluble drugs
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
CZ2006443A3 (cs) 1999-03-31 2019-02-20 Janssen Pharmaceutica N. V. Hydrofilní formulace s řízeným uvolňováním, která obsahuje předželatinovaný škrob, způsob její přípravy a léková forma s jejím obsahem
JP4696210B2 (ja) * 2000-06-07 2011-06-08 トーアエイヨー株式会社 イソソルビド‐５‐モノニトレートを有効成分とする徐放性錠剤及びその製造方法
KR100446818B1 (ko) * 2001-11-06 2004-09-01 김재윤 질산 이소소르비드 서방성 펠렛 제형
TWI338583B (en) * 2004-05-20 2011-03-11 Otsuka Pharma Co Ltd Solid pharmaceutical formulation
US20080286343A1 (en) * 2007-05-16 2008-11-20 Dzenana Cengic Solid form
US20230263735A1 (en) * 2020-07-13 2023-08-24 Kirin Holdings Kabushiki Kaisha Film coated tablet
CN113476416B (zh) * 2021-08-03 2022-02-18 北京阳光诺和药物研究股份有限公司 一种治疗血管舒张的药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3328094A1 (de) * 1983-08-04 1985-02-21 H. Trommsdorff GmbH & Co, 5110 Alsdorf Phlegmatisierte pharmazeutische zubereitung von explosionsfaehigen salpetersaeureestern
DE3328894A1 (de) * 1983-08-10 1985-02-28 Kathrein-Werke Kg, 8200 Rosenheim Antennen-kombination
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
IT1187750B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di compresse,anche a rilascio prolungato,di iscsorbide-5-mononitrato stabilizzato e formulazioni cosi' ottenute
FR2618073B1 (fr) * 1987-07-16 1990-09-07 Pf Medicament Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation

Also Published As

Publication number Publication date
DE69109419T2 (de) 1996-02-01
EP0477061A1 (fr) 1992-03-25
FR2666506B1 (es) 1994-12-16
DE69109419D1 (de) 1995-06-08
ATE121936T1 (de) 1995-05-15
US5334393A (en) 1994-08-02
EP0477061B1 (fr) 1995-05-03
FR2666506A1 (fr) 1992-03-13

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