ES2074529T3 - Poliamidas que contienen cadenas laterales funcionalizadas utiles como agentes hipolipidemicos solubles en agua. - Google Patents

Poliamidas que contienen cadenas laterales funcionalizadas utiles como agentes hipolipidemicos solubles en agua.

Info

Publication number
ES2074529T3
ES2074529T3 ES90250078T ES90250078T ES2074529T3 ES 2074529 T3 ES2074529 T3 ES 2074529T3 ES 90250078 T ES90250078 T ES 90250078T ES 90250078 T ES90250078 T ES 90250078T ES 2074529 T3 ES2074529 T3 ES 2074529T3
Authority
ES
Spain
Prior art keywords
soluble
water
side chains
hypolipidemic agents
polyamides containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90250078T
Other languages
English (en)
Inventor
Walton Bernard Caldwell
Paul William Erhardt
William Carl Lumma Jr
Gary Bruce Phillips
Kenneth Jay Shaw
William Vroom Taggart
Bhaskar Rao Vennepalli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Berlex Laboratories Inc
Original Assignee
Berlex Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlex Laboratories Inc filed Critical Berlex Laboratories Inc
Application granted granted Critical
Publication of ES2074529T3 publication Critical patent/ES2074529T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
    • C08G73/1092—Polysuccinimides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

LA INVENCION SE REFIERE A DERIVADOS DE ACIDO POLIANHIDROASPARTICO QUE SON POLIMEROS SOLUBLES EN AGUA NO SISTEMATICOS Y QUE PUEDEN SER AGENTES REDUCTORES DE LIPIDOS. TAMBIEN SE TRATAN LAS COMPOSICIONES Y FORMULACIONES FARMACEUTICAS QUE INCORPORAN ESTOS COMPUESTOS
ES90250078T 1989-03-23 1990-03-21 Poliamidas que contienen cadenas laterales funcionalizadas utiles como agentes hipolipidemicos solubles en agua. Expired - Lifetime ES2074529T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32801489A 1989-03-23 1989-03-23

Publications (1)

Publication Number Publication Date
ES2074529T3 true ES2074529T3 (es) 1995-09-16

Family

ID=23279131

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90250078T Expired - Lifetime ES2074529T3 (es) 1989-03-23 1990-03-21 Poliamidas que contienen cadenas laterales funcionalizadas utiles como agentes hipolipidemicos solubles en agua.

Country Status (7)

Country Link
EP (1) EP0389079B1 (es)
JP (1) JP2909500B2 (es)
AT (1) ATE121430T1 (es)
CA (1) CA2012564A1 (es)
DE (1) DE69018681T2 (es)
DK (1) DK0389079T3 (es)
ES (1) ES2074529T3 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2056035A1 (en) * 1991-06-18 1992-12-19 Walton B. Caldwell Polyamides bearing functionalized side chains useful as water soluble hopolipidemic agents
DE59209709D1 (de) * 1991-12-20 1999-07-15 Hoechst Ag Polyaspartamidderivate als Adsorptionsmittel für Gallensäuren, mit Gallensäuren beladene Polyaspartamidderivate und Verfahren zu deren Herstellung sowie deren Anwendung als Arzneimittel
EP0622078B1 (en) * 1992-01-14 1999-09-01 Hisamitsu Pharmaceutical Co., Inc. Cholesterol level depressant
US5686066A (en) * 1995-10-05 1997-11-11 Mitsui Toatsu Chemicals, Inc. Polyaspartic acid Zwitterionic derivatives, preparation processes thereof, hair-treating compositions and cosmetic compositions
AUPO104496A0 (en) * 1996-07-17 1996-08-08 Biomolecular Research Institute Limited Angiogenic inhibitory compounds
AUPO104396A0 (en) * 1996-07-17 1996-08-08 Biomolecular Research Institute Limited Antiviral linear polymers
CN119060325B (zh) * 2024-11-01 2025-03-11 浙江农林大学 一种富含1,3-二羰基侧链聚赖氨酸及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1045109B (it) * 1969-07-03 1980-05-10 Inst Sieroterapico E Vaccino G Foli idrossi etil asparagina e metodo per la sua produzione
CS252559B1 (en) * 1985-03-22 1987-09-17 Frantisek Rypacek Polymer stabilizer of emulsion type water in oil
CH667874A5 (fr) * 1985-12-19 1988-11-15 Battelle Memorial Institute Polypeptide synthetique biodegradable et son utilisation pour la preparation de medicaments.
FR2603888B1 (fr) * 1986-09-16 1990-12-21 Panmedica Sa Esters d'amino acides du trimethyl cyclohexanol, procede de preparation et utilisation comme medicaments

Also Published As

Publication number Publication date
JP2909500B2 (ja) 1999-06-23
DK0389079T3 (da) 1995-09-18
DE69018681D1 (de) 1995-05-24
CA2012564A1 (en) 1990-09-23
ATE121430T1 (de) 1995-05-15
JPH02281032A (ja) 1990-11-16
EP0389079A2 (en) 1990-09-26
EP0389079A3 (en) 1991-08-07
EP0389079B1 (en) 1995-04-19
DE69018681T2 (de) 1996-01-25

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