ES2075338T3 - Formulacion de naproxeno, de absorcion controlada, para administracion una vez al dia. - Google Patents

Formulacion de naproxeno, de absorcion controlada, para administracion una vez al dia.

Info

Publication number
ES2075338T3
ES2075338T3 ES91300243T ES91300243T ES2075338T3 ES 2075338 T3 ES2075338 T3 ES 2075338T3 ES 91300243 T ES91300243 T ES 91300243T ES 91300243 T ES91300243 T ES 91300243T ES 2075338 T3 ES2075338 T3 ES 2075338T3
Authority
ES
Spain
Prior art keywords
naproxeno
day
formulation
administration once
controlled absorption
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91300243T
Other languages
English (en)
Inventor
Edward Anthony Bourke
Seamus Mulligan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Perrigo Co PLC
Original Assignee
Elan Corp PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11007725&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2075338(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Elan Corp PLC filed Critical Elan Corp PLC
Application granted granted Critical
Publication of ES2075338T3 publication Critical patent/ES2075338T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

UNA FORMULACION DEL NAPROXENO PARA LA ADMINISTRACION ORAL DE UNA VEZ AL DIA, QUE CONSTA DE UNA PRIMERA PARTE DEL NAPROXENO FORMULADO EN FORMA DE PILDORAS CON MULTIGRANULADO CON EL FIN DE QUE EL FARMACO SE LIBERE EN UNA CANTIDAD SUFICIENTE PARA MANTENER NIVELES SANGUINEOS TERAPEUTICAMENTE EFECTIVOS SUSTANCIALMENTE DURANTE 24 HORAS CUANDO SE ADMINISTRA CADA DIA EN UNA TOMA DIARIA. UNA SEGUNDA PARTE DEL NAPROXENO FORMULADO QUE SIRVE PARA QUE SE LIBERE EL FARMACO INMEDIATAMENTE DESPUES DE SU ADMINISTRACION, CON EL FIN DE OBTENER UNA RESPUESTA TERAPEUTICA RELATIVAMENTE INMEDIATA.
ES91300243T 1990-01-15 1991-01-14 Formulacion de naproxeno, de absorcion controlada, para administracion una vez al dia. Expired - Lifetime ES2075338T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE14990A IE66933B1 (en) 1990-01-15 1990-01-15 Controlled absorption naproxen formulation for once-daily administration

Publications (1)

Publication Number Publication Date
ES2075338T3 true ES2075338T3 (es) 1995-10-01

Family

ID=11007725

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91300243T Expired - Lifetime ES2075338T3 (es) 1990-01-15 1991-01-14 Formulacion de naproxeno, de absorcion controlada, para administracion una vez al dia.

Country Status (15)

Country Link
US (1) US5637320A (es)
EP (1) EP0438249B1 (es)
JP (1) JP3157182B2 (es)
AT (1) ATE126055T1 (es)
AU (1) AU639519B2 (es)
CA (1) CA2034096C (es)
DE (1) DE69111832T2 (es)
DK (1) DK0438249T3 (es)
ES (1) ES2075338T3 (es)
GR (1) GR3017633T3 (es)
IE (1) IE66933B1 (es)
IL (1) IL96900A (es)
NZ (1) NZ236762A (es)
PH (1) PH30694A (es)
ZA (1) ZA91274B (es)

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Also Published As

Publication number Publication date
AU6933291A (en) 1991-07-18
DK0438249T3 (da) 1995-09-18
DE69111832D1 (de) 1995-09-14
PH30694A (en) 1997-09-16
IE66933B1 (en) 1996-02-07
JPH04217918A (ja) 1992-08-07
IL96900A (en) 1995-12-31
IL96900A0 (en) 1992-03-29
ZA91274B (en) 1991-10-30
NZ236762A (en) 1992-12-23
ATE126055T1 (de) 1995-08-15
CA2034096C (en) 2002-03-26
CA2034096A1 (en) 1991-07-16
AU639519B2 (en) 1993-07-29
DE69111832T2 (de) 1996-03-14
EP0438249A1 (en) 1991-07-24
JP3157182B2 (ja) 2001-04-16
IE900149A1 (en) 1991-07-17
EP0438249B1 (en) 1995-08-09
GR3017633T3 (en) 1996-01-31
US5637320A (en) 1997-06-10

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