ES2076170T3 - Metodo para la produccion de derivados de 3-exometilencefam. - Google Patents

Metodo para la produccion de derivados de 3-exometilencefam.

Info

Publication number
ES2076170T3
ES2076170T3 ES89108427T ES89108427T ES2076170T3 ES 2076170 T3 ES2076170 T3 ES 2076170T3 ES 89108427 T ES89108427 T ES 89108427T ES 89108427 T ES89108427 T ES 89108427T ES 2076170 T3 ES2076170 T3 ES 2076170T3
Authority
ES
Spain
Prior art keywords
lead
exometilencefam
derivatives
cefem
exp1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89108427T
Other languages
English (en)
Inventor
Sigeru Torii
Hideo Tanaka
Masatoshi Taniguchi
Michio Sasaoka
Norio Saito
Takashi Shiroi
Shigemitsu Nagao
Ryo Kikuchi
Yutaka Kameyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Original Assignee
Otsuka Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd filed Critical Otsuka Chemical Co Ltd
Application granted granted Critical
Publication of ES2076170T3 publication Critical patent/ES2076170T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

SE PRESENTA UN METODO DE PRODUCCION DE 3 - EXOMETILENCEFAM DE LA FORMULA II DONDE R EXP1 ES AMINO O AMINO SUSTITUIDO Y R (AL CUADRADO) ES UN GRUPO PROTECTOR DE CARBOXILO QUE COMPRENDE REACCION DE UN CEFEM DE LA FORMULA I DONDE R EXP1 Y R (AL CUADRADO) SON COMO SE DEFINE ARRIBA Y X ES HALOGENO CON METAL DE PLOMO MANTENIENDO EL PH DEL SISTEMA DE REACCION A 0,1 A 8. EL CEFEM (I) PUEDE REACCIONAR CON UNA CANTIDAD CATALITICA DE PLOMO O UN COMPUESTO DE PLOMO EN PRESENCIA DE UN METAL CON UNA MAYOR TENDENCIA DE IONIZACION QUE EL PLOMO.
ES89108427T 1988-05-11 1989-05-10 Metodo para la produccion de derivados de 3-exometilencefam. Expired - Lifetime ES2076170T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63115711A JP2750355B2 (ja) 1988-05-11 1988-05-11 ３−エキソメチレンセファム誘導体の製造法

Publications (1)

Publication Number Publication Date
ES2076170T3 true ES2076170T3 (es) 1995-11-01

Family

ID=14669300

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89108427T Expired - Lifetime ES2076170T3 (es) 1988-05-11 1989-05-10 Metodo para la produccion de derivados de 3-exometilencefam.

Country Status (5)

Country Link
US (1) US4958018A (es)
EP (1) EP0341694B1 (es)
JP (1) JP2750355B2 (es)
DE (1) DE68924093T2 (es)
ES (1) ES2076170T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8816546D0 (en) * 1988-07-12 1988-08-17 Baldwin J E Process for preparing intermediates
GB9203327D0 (en) * 1992-02-17 1992-04-01 Erba Carlo Spa Process for the synthesis of exomethylenecephams
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
WO1999010352A1 (en) * 1997-08-25 1999-03-04 Otsuka Chemical Co., Ltd. Cephalosporin crystals and process for producing the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1022542A (en) * 1973-01-09 1977-12-13 Bruno Fechtig Process for the manufacture of methylene compounds
JPS5770893A (en) * 1980-10-16 1982-05-01 Fujisawa Pharmaceut Co Ltd Preparation of cephalosporin derivative
US4354022A (en) * 1981-06-05 1982-10-12 Fujisawa Pharmaceutical Co., Ltd. Process for preparing 3-methylenecepham compounds or a salt thereof
JPS58222092A (ja) * 1982-06-18 1983-12-23 Fujisawa Pharmaceut Co Ltd ３−メチレンセフアム化合物またはその塩類の製造法
JPS5946952A (ja) * 1982-09-13 1984-03-16 株式会社日立製作所 レ−ザメス装置
US4558123A (en) * 1983-07-22 1985-12-10 Eli Lilly And Company 3-Exomethylene cephalosporins
JPS60187689A (ja) * 1984-03-06 1985-09-25 Otsuka Chem Co Ltd ３−エキソメチレンセフアム誘導体の製造法
JPS6153289A (ja) * 1984-08-24 1986-03-17 Fujisawa Pharmaceut Co Ltd ３−メチレンセフアム化合物またはその塩類の製造法

Also Published As

Publication number Publication date
DE68924093D1 (de) 1995-10-12
EP0341694B1 (en) 1995-09-06
JPH01287087A (ja) 1989-11-17
JP2750355B2 (ja) 1998-05-13
EP0341694A2 (en) 1989-11-15
US4958018A (en) 1990-09-18
EP0341694A3 (en) 1991-08-28
DE68924093T2 (de) 1996-05-02

Similar Documents

Publication Publication Date Title
ES2071020T3 (es) Derivados de n-fenilpirazol.
DE3574931D1 (de) Verfahren und anlage zur herstellung von sterilem wasser und sterilen waessrigen loesungen.
UA21892A (uk) Спосіб боротьби з бур'яhами
DE3775527D1 (de) 1,5-diphenylpyrazol-3-carbonsaeurederivate zum schuetzen von kulturpflanzen.
GT198400014A (es) Mejoras en o relativas a fenetanolaminas.
ES8602022A1 (es) Un procedimiento para preparar un derivado de 4'-dimetil-4-epipodofilotoxina
ES2027749T3 (es) Agente protector de la madera.
ATE113261T1 (de) Korrosionsschutz.
ATE56211T1 (de) 2-phenylbenzoxepin-derivat.
BR8206619A (pt) Processo para recuperacao de oxido de etileno de solucoes aquosas
SE8404699D0 (sv) Makrofagstimulerande komposition jemte forfarande for dess framstellning
IT8522253A0 (it) Procedimento ciclico per produrre soluzioni alcaline di carbammato di cellulosa, precipitare il carbammato e recuperare i prodotti chimici.
DE3852402D1 (de) Galliumnitridartige Halbleiterverbindung und daraus bestehende lichtemittierende Vorrichtung sowie Verfahren zu deren Herstellung.
ES8305700A1 (es) Un procedimiento para la preparacion de derivados dipeptidicos.
FR2692812B1 (fr) Microcapsules contenant au moins un principe actif, leurs applications et procédé de préparation de microcapsules renfermant au moins un principe actif.
IT8522252A0 (it) Procedimento ciclico per produrre soluzioni alcaline di carbammato di cellulosa, precipitare il carbammato e recuperare i prodotti chimici.
ES2066800T3 (es) Naftalocianinas de silicio asi como peliculas de recubrimiento delgadas radiosensibles, que contienen estos compuestos.
GB1271337A (en) S-chloromethyl compounds of 2-mercaptobenzothiazoles, 2-mercaptobenzoxazoles and 2-mercaptobenzimidazoles
ES415226A1 (es) Procedimiento para la obtencion de ascorbato de vincamina.
AU556123B2 (en) Concentration of organic chemicals from aqueous solutions
FI960568A0 (fi) Menetelmä metallien talteenottamiseksi
NO156774C (no) Fremgangsmaate for behandling av forurensede, alkaliske, vandige stretford-prosess-opploesninger.
SE8405956D0 (sv) Forfarande for behandling av spik
FI871191A7 (fi) Menetelmä kiniinin, kinidiinin ja johdannaisten mikrobiologiseksi hyd roksyloimiseksi.
FR2360346A1 (fr) Gel actif et son procede de production

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 341694

Country of ref document: ES