ES2076758T3 - Cristalizacion de macromoleculas biologicas en microgravedad. - Google Patents

Cristalizacion de macromoleculas biologicas en microgravedad.

Info

Publication number
ES2076758T3
ES2076758T3 ES92908432T ES92908432T ES2076758T3 ES 2076758 T3 ES2076758 T3 ES 2076758T3 ES 92908432 T ES92908432 T ES 92908432T ES 92908432 T ES92908432 T ES 92908432T ES 2076758 T3 ES2076758 T3 ES 2076758T3
Authority
ES
Spain
Prior art keywords
lid
microgravity
crystallization
biological macromolecules
bottle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92908432T
Other languages
English (en)
Inventor
Charles E Bugg
Lucas Lawrence J De
Tattanahalli L Nagabhushan
Paul P Trotta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UAB Research Foundation
Merck Sharp and Dohme LLC
Original Assignee
UAB Research Foundation
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UAB Research Foundation, Schering Corp filed Critical UAB Research Foundation
Application granted granted Critical
Publication of ES2076758T3 publication Critical patent/ES2076758T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B30/00—Production of single crystals or homogeneous polycrystalline material with defined structure characterised by the action of electric or magnetic fields, wave energy or other specific physical conditions
    • C30B30/08—Production of single crystals or homogeneous polycrystalline material with defined structure characterised by the action of electric or magnetic fields, wave energy or other specific physical conditions in conditions of zero-gravity or low gravity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/306—Extraction; Separation; Purification by precipitation by crystallization
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/54—Organic compounds
    • C30B29/58—Macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Closures For Containers (AREA)

Abstract

SE DESCRIBE UN APARATO QUE CONTIENE AL MENOS UN CONTENEDOR QUE TIENE EXTREMOS OPUESTOS Y UNA TAPA CONDUCTORA TERMICAMENTE EN UN EXTREMO DEL MISMO. AL MENOS UN FRASCO QUE TIENE TAPON CONDUCTOR TERMICAMENTE Y DISPUESTO DENTRO DEL CONTENEDOR DE FORMA QUE EL TAPON HAGA CONTACTO CON LA TAPA PARA QUE PERMITA LA TRANSFERENCIA DE CALOR ENTRE ELLOS; UN DISPOSITIVO PARA MANTENER LA TAPA EN CONTACTO CON UNA FUENTE DE CALOR VARIABLE DE MANERA QUE SE OBTIENE UN GRADIENTE DE TEMPERATURA EN EL FRASCO.
ES92908432T 1991-02-25 1992-02-24 Cristalizacion de macromoleculas biologicas en microgravedad. Expired - Lifetime ES2076758T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65994891A 1991-02-25 1991-02-25
US83665892A 1992-02-18 1992-02-18

Publications (1)

Publication Number Publication Date
ES2076758T3 true ES2076758T3 (es) 1995-11-01

Family

ID=27097940

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92908432T Expired - Lifetime ES2076758T3 (es) 1991-02-25 1992-02-24 Cristalizacion de macromoleculas biologicas en microgravedad.

Country Status (8)

Country Link
EP (1) EP0573599B1 (es)
JP (1) JPH0768080B2 (es)
AT (1) ATE123080T1 (es)
DE (1) DE69202701T2 (es)
DK (1) DK0573599T3 (es)
ES (1) ES2076758T3 (es)
GR (1) GR3017163T3 (es)
WO (1) WO1992014869A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07185313A (ja) * 1993-12-28 1995-07-25 Fujitsu Ltd 微小重力環境下で使用される製造装置
JP3094880B2 (ja) * 1995-03-01 2000-10-03 住友金属工業株式会社 有機化合物の結晶化制御方法およびそれに用いる結晶化制御用固体素子
DE102007020671A1 (de) 2007-05-01 2008-11-06 Justus-Liebig-Universität Giessen Verfahren und Vorrichtung zum kontaktfreien Materialwachstum in einer strömenden Lösung (FLow suspended solution growth (FSSG))
US11698194B2 (en) 2019-09-16 2023-07-11 Nanoracks, Llc Space oven

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3738840A1 (de) * 1987-08-12 1989-02-23 Intospace Gmbh Kristallisationseinrichtung
FR2627703B1 (fr) * 1988-02-29 1990-08-10 Aerospatiale Systeme de cristallogenese, notamment pour vaisseau spatial

Also Published As

Publication number Publication date
DK0573599T3 (da) 1995-07-24
EP0573599A1 (en) 1993-12-15
DE69202701T2 (de) 1995-09-28
JPH0768080B2 (ja) 1995-07-26
JPH06508813A (ja) 1994-10-06
ATE123080T1 (de) 1995-06-15
EP0573599B1 (en) 1995-05-24
GR3017163T3 (en) 1995-11-30
DE69202701D1 (de) 1995-06-29
WO1992014869A1 (en) 1992-09-03

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