ES2078839A1 - Procedimiento de obtencion de fosfinas substituidas con oxaza. - Google Patents
Procedimiento de obtencion de fosfinas substituidas con oxaza.Info
- Publication number
- ES2078839A1 ES2078839A1 ES09250040A ES9250040A ES2078839A1 ES 2078839 A1 ES2078839 A1 ES 2078839A1 ES 09250040 A ES09250040 A ES 09250040A ES 9250040 A ES9250040 A ES 9250040A ES 2078839 A1 ES2078839 A1 ES 2078839A1
- Authority
- ES
- Spain
- Prior art keywords
- oxaza
- substituted phosphines
- phosphines
- compounds
- isoxazepinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003003 phosphines Chemical class 0.000 title abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- QXDOFVVNXBGLKK-UHFFFAOYSA-N 3-Isoxazolidinone Chemical compound OC1=NOCC1 QXDOFVVNXBGLKK-UHFFFAOYSA-N 0.000 abstract 1
- FBXGQDUVJBKEAJ-UHFFFAOYSA-N 4h-oxazin-3-one Chemical compound O=C1CC=CON1 FBXGQDUVJBKEAJ-UHFFFAOYSA-N 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000002917 arthritic effect Effects 0.000 abstract 1
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical group [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/6533—Six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE FOSFINAS SUSTITUIDAS CON OXAZA. LA INVENCION SE REFIERE A UN PROCEDIMIENTO DE OBTENCION DE UNA NUEVA CLASE DE FOSFINAS, EN LAS QUE EL FOSFORO ESTA LIGADO A UN HETEROCICLO DE 5, 6 O 7 MIEMBROS, QUE CONTIENE UN NUCLEO OXAZA COMO, POR EJEMPLO, ISOXAZOLIDINONA, OXAZINONA E ISOXAZEPINONA. ADEMAS DE SU ACTIVIDAD ANTI-INFLAMATORIA ALGUNOS DE LOS COMPUESTOS DE FOSFINA TIENEN UTILIDAD COMO INTERMEDIARIOS EN LA PRODUCCION DE HETEROCICLOS SUSTITUIDOS CON BENZILIDENO, COMPUESTOS QUE HAN SIDO PROBADOS, TAMBIEN EFECTIVOS EN EL TRATAMIENTO DE LA INFLAMACION Y OTRAS CONDICIONES ARTRITICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/656,505 US5128330A (en) | 1991-02-19 | 1991-02-19 | Oxazinone substituted phosphines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2078839A1 true ES2078839A1 (es) | 1995-12-16 |
| ES2078839B1 ES2078839B1 (es) | 1996-08-01 |
Family
ID=24633317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09250040A Expired - Fee Related ES2078839B1 (es) | 1991-02-19 | 1992-02-19 | Procedimiento de obtencion de fosfinas substituidas con oxaza. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5128330A (es) |
| EP (1) | EP0572532B1 (es) |
| AT (1) | ATE152622T1 (es) |
| AU (1) | AU1440792A (es) |
| CH (1) | CH683524A5 (es) |
| DE (1) | DE69219588T2 (es) |
| ES (1) | ES2078839B1 (es) |
| FR (1) | FR2672894B1 (es) |
| IE (1) | IE71177B1 (es) |
| NZ (1) | NZ241636A (es) |
| PT (1) | PT100143B (es) |
| WO (1) | WO1992014459A2 (es) |
| ZA (1) | ZA921212B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20170058917A (ko) * | 2014-07-30 | 2017-05-29 | 아이씨비 파아마 스폴카 자우나 토마츠 스위에토슬라우스키, 파웰 스위에토슬라우스키 | 외부기생충박멸 활성을 갖는 액체 확산 조성물, 의학과 수의학 및 농학, 원예학 및/또는 조경 환경들에서 외부기생충들을 구제하기 위한 방법 및 그 용도 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4562185A (en) * | 1983-03-30 | 1985-12-31 | Bayer Aktiengesellschaft | Five-membered nitrogen-containing hetero-cyclic compounds and their use as pest-combating agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230849A (en) * | 1979-07-02 | 1980-10-28 | Antibioticos, S.A. | Process for the activation of carboxylic acids |
| JPH07121905B2 (ja) * | 1986-11-06 | 1995-12-25 | エーザイ株式会社 | ２−ピロリドン誘導体 |
| US4892870A (en) * | 1988-08-01 | 1990-01-09 | Biofor, Ltd. | Oxaza heterocycles and pharmaceutical compositions containing same |
| US4959482A (en) * | 1988-09-26 | 1990-09-25 | Biofor, Ltd. | Pyrrolidinone compounds and pharamaceutical compositions containing same |
| US5128328A (en) * | 1991-10-25 | 1992-07-07 | American Home Products Corporation | Heterocyclic bisphosphonic acid derivatives |
-
1991
- 1991-02-19 US US07/656,505 patent/US5128330A/en not_active Expired - Fee Related
-
1992
- 1992-02-18 NZ NZ24163692A patent/NZ241636A/en unknown
- 1992-02-18 IE IE920505A patent/IE71177B1/en not_active IP Right Cessation
- 1992-02-19 ES ES09250040A patent/ES2078839B1/es not_active Expired - Fee Related
- 1992-02-19 AU AU14407/92A patent/AU1440792A/en not_active Abandoned
- 1992-02-19 EP EP92907217A patent/EP0572532B1/en not_active Expired - Lifetime
- 1992-02-19 AT AT92907217T patent/ATE152622T1/de not_active IP Right Cessation
- 1992-02-19 WO PCT/US1992/001067 patent/WO1992014459A2/en not_active Ceased
- 1992-02-19 DE DE69219588T patent/DE69219588T2/de not_active Expired - Fee Related
- 1992-02-19 PT PT100143A patent/PT100143B/pt not_active IP Right Cessation
- 1992-02-19 FR FR9201877A patent/FR2672894B1/fr not_active Expired - Fee Related
- 1992-02-19 CH CH488/92A patent/CH683524A5/de not_active IP Right Cessation
- 1992-02-19 ZA ZA921212A patent/ZA921212B/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4562185A (en) * | 1983-03-30 | 1985-12-31 | Bayer Aktiengesellschaft | Five-membered nitrogen-containing hetero-cyclic compounds and their use as pest-combating agents |
Also Published As
| Publication number | Publication date |
|---|---|
| PT100143B (pt) | 1999-08-31 |
| DE69219588T2 (de) | 1998-01-02 |
| US5128330A (en) | 1992-07-07 |
| EP0572532A1 (en) | 1993-12-08 |
| WO1992014459A2 (en) | 1992-09-03 |
| FR2672894A1 (fr) | 1992-08-21 |
| AU1440792A (en) | 1992-09-15 |
| IE71177B1 (en) | 1997-01-29 |
| CH683524A5 (de) | 1994-03-31 |
| DE69219588D1 (de) | 1997-06-12 |
| ES2078839B1 (es) | 1996-08-01 |
| FR2672894B1 (fr) | 1999-02-12 |
| NZ241636A (en) | 1994-07-26 |
| PT100143A (pt) | 1993-05-31 |
| IE920505A1 (en) | 1992-08-26 |
| WO1992014459A3 (en) | 1992-10-15 |
| ZA921212B (en) | 1992-12-30 |
| ATE152622T1 (de) | 1997-05-15 |
| EP0572532A4 (en) | 1994-03-21 |
| EP0572532B1 (en) | 1997-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 19920219 Kind code of ref document: B1 Effective date: 19920219 |
|
| FD1A | Patent lapsed |
Effective date: 20040503 |