ES2079391T3 - Procedimiento para la obtencion de 2,7-diazabiciclo(3.3.0)octanos. - Google Patents

Procedimiento para la obtencion de 2,7-diazabiciclo(3.3.0)octanos.

Info

Publication number
ES2079391T3
ES2079391T3 ES90106459T ES90106459T ES2079391T3 ES 2079391 T3 ES2079391 T3 ES 2079391T3 ES 90106459 T ES90106459 T ES 90106459T ES 90106459 T ES90106459 T ES 90106459T ES 2079391 T3 ES2079391 T3 ES 2079391T3
Authority
ES
Spain
Prior art keywords
octanes
diazabiciclo
procedure
obtaining
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90106459T
Other languages
English (en)
Inventor
Thomas Dr Schenke
Uwe Dr Petersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2079391T3 publication Critical patent/ES2079391T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Oxide Ceramics (AREA)

Abstract

EL INVENTO CONCIERNE A LOS 2,7-DIAZABICICLO(3,3,0)OCTANOS DE FORMULA (I) (FORMULA), EN LA QUE LOS SUSTITUYENTES R1 A R8 TIENEN EL SIGNIFICADO DADO EN LA MEMORIA, Y A UN PROCEDIMIENTO PARA SU PRODUCCION. LOS COMPUESTOS SEGUN EL INVENTO CONSTITUYEN VALIOSOS PRODUCTOS INTERMEDIOS PARA LA PRODUCCION DE ACIDOS QUINOLONCARBOXILICOS DE ELEVADA ACTIVIDAD ANTIBACTERIAL. OTRO OBJETIVO MAS DEL INVENTO LO CONSTITUYEN TAMBIEN LOS COMPUESTOS DE FORMULA (II) (FORMULA), EN LA QUE R1 A R8 TIENEN IGUALMENTE EL SIGNIFICADO DADO EN LA MEMORIA.
ES90106459T 1989-04-17 1990-04-04 Procedimiento para la obtencion de 2,7-diazabiciclo(3.3.0)octanos. Expired - Lifetime ES2079391T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3912509 1989-04-17
DE3932903 1989-10-03

Publications (1)

Publication Number Publication Date
ES2079391T3 true ES2079391T3 (es) 1996-01-16

Family

ID=25879982

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90106459T Expired - Lifetime ES2079391T3 (es) 1989-04-17 1990-04-04 Procedimiento para la obtencion de 2,7-diazabiciclo(3.3.0)octanos.

Country Status (12)

Country Link
US (1) US5071999A (es)
EP (1) EP0393424B1 (es)
JP (1) JPH02292288A (es)
KR (1) KR0166963B1 (es)
AT (1) ATE128466T1 (es)
CA (1) CA2014478A1 (es)
DE (1) DE59009705D1 (es)
DK (1) DK0393424T3 (es)
ES (1) ES2079391T3 (es)
GR (1) GR3017384T3 (es)
IE (1) IE68591B1 (es)
PT (1) PT93702B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177210A (en) * 1989-04-17 1993-01-05 Bayer Aktiengesellschaft Preparation of 2,7-diazabicyclo(3.3.0)octanes
KR960003611B1 (ko) * 1992-07-23 1996-03-20 재단법인 한국화학연구소 신규한 디아자비시클로 알켄 유도체 및 그의 제조방법
MXPA02005884A (es) 1999-12-14 2002-10-23 Neurosearch As Heteroaril-diazabicicloalcanos novedosos.
US6809105B2 (en) * 2000-04-27 2004-10-26 Abbott Laboratories Diazabicyclic central nervous system active agents
MY137020A (en) * 2000-04-27 2008-12-31 Abbott Lab Diazabicyclic central nervous system active agents
CA2440803A1 (en) * 2001-03-07 2002-09-12 Pfizer Products Inc. Modulators of chemokine receptor activity
WO2004092173A2 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. A2a adenosine receptor antagonists
US20050065178A1 (en) 2003-09-19 2005-03-24 Anwer Basha Substituted diazabicycloakane derivatives
US7728031B2 (en) 2006-02-24 2010-06-01 Abbott Laboratories Octahydro-pyrrolo[3,4-b]pyrrole derivatives
US8735411B2 (en) * 2006-10-02 2014-05-27 Abbvie Inc. Macrocyclic benzofused pyrimidine derivatives
US7985745B2 (en) * 2006-10-02 2011-07-26 Abbott Laboratories Method for pain treatment
US20080159958A1 (en) * 2006-12-27 2008-07-03 Abbott Laboratories Determination of histamine-3 bioactivity
RU2486187C2 (ru) 2007-09-11 2013-06-27 Эбботт Лэборетриз N-ОКСИДЫ ОКТАГИДРО-ПИРРОЛО[3,4-b]ПИРРОЛА
US8278313B2 (en) * 2008-03-11 2012-10-02 Abbott Laboratories Macrocyclic spiro pyrimidine derivatives
JP6251749B2 (ja) 2012-09-27 2017-12-20 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 置換されていても良いフェニルおよびピリジルピロリジン類の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198372B (en) * 1984-07-18 1989-10-30 Sandoz Ag Insecticide compositions containing carbaminic acid derivatives as active components and process for producing th the active components
JPH0676400B2 (ja) * 1987-08-25 1994-09-28 大日本製薬株式会社 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren

Also Published As

Publication number Publication date
JPH02292288A (ja) 1990-12-03
PT93702A (pt) 1990-11-20
DE59009705D1 (de) 1995-11-02
ATE128466T1 (de) 1995-10-15
IE901343L (en) 1990-10-17
CA2014478A1 (en) 1990-10-17
EP0393424B1 (de) 1995-09-27
EP0393424A3 (de) 1991-10-16
GR3017384T3 (en) 1995-12-31
KR0166963B1 (ko) 1999-01-15
IE68591B1 (en) 1996-06-26
KR900016215A (ko) 1990-11-12
DK0393424T3 (da) 1996-02-05
PT93702B (pt) 1996-08-30
US5071999A (en) 1991-12-10
EP0393424A2 (de) 1990-10-24

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