ES2081864T3 - Metodo para purificar una proteina de la membrana exterior de haemophilus influenzae. - Google Patents

Metodo para purificar una proteina de la membrana exterior de haemophilus influenzae.

Info

Publication number
ES2081864T3
ES2081864T3 ES90105205T ES90105205T ES2081864T3 ES 2081864 T3 ES2081864 T3 ES 2081864T3 ES 90105205 T ES90105205 T ES 90105205T ES 90105205 T ES90105205 T ES 90105205T ES 2081864 T3 ES2081864 T3 ES 2081864T3
Authority
ES
Spain
Prior art keywords
protein
purify
outer membrane
haemophilus influenzae
insoluble fraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90105205T
Other languages
English (en)
Inventor
Timothy F Murphy
Michael A Apicella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of the State University of New York
Original Assignee
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of the State University of New York filed Critical Research Foundation of the State University of New York
Application granted granted Critical
Publication of ES2081864T3 publication Critical patent/ES2081864T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

UN METODO DE PURIFICAR UNA PROTEINA DE MEMBRANA EXTERNA IMMUNOGENICA DE H.FLU. LOS PASOS QUE COMPRENDE, FORMACION DE UNA FRACCION INSOLUBLE QUE COMPRENDE LA PROTEINA DE MEMBRANA EXTERNA ASOCIADA CON EL PEPTIDOGLICAN DE LA H.FLU.; DIGERIR LA RNA CONTAMINADA DE LA FRACCION INSOLUBLE; SEPARAR LA PROTEINA DE LA FRACCION INSOLUBLE DENTRO DE LA SUPERNATANTE; Y CONCENTRAR MLA PROTEINA DE MEMBRANA EXTERNA SOLUBILIZADA.
ES90105205T 1989-03-29 1990-03-20 Metodo para purificar una proteina de la membrana exterior de haemophilus influenzae. Expired - Lifetime ES2081864T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33022989A 1989-03-29 1989-03-29

Publications (1)

Publication Number Publication Date
ES2081864T3 true ES2081864T3 (es) 1996-03-16

Family

ID=23288845

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90105205T Expired - Lifetime ES2081864T3 (es) 1989-03-29 1990-03-20 Metodo para purificar una proteina de la membrana exterior de haemophilus influenzae.

Country Status (8)

Country Link
EP (1) EP0389925B1 (es)
JP (1) JPH03175991A (es)
AT (1) ATE132160T1 (es)
CA (1) CA2012676A1 (es)
DE (1) DE69024392T2 (es)
DK (1) DK78990A (es)
ES (1) ES2081864T3 (es)
IE (1) IE71949B1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202219D0 (en) * 1992-02-03 1992-03-18 Connaught Lab A synthetic heamophilus influenzae conjugate vaccine
US5681570A (en) * 1995-01-12 1997-10-28 Connaught Laboratories Limited Immunogenic conjugate molecules
DE19612966B4 (de) 1996-04-01 2009-12-10 Novartis Vaccines And Diagnostics Gmbh & Co. Kg MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren
TW570803B (en) * 1997-04-09 2004-01-11 Duphar Int Res Influenza vaccine
WO2001000668A1 (en) * 1999-06-25 2001-01-04 American Cyanamid Company Extraction of integral membrane proteins
DE10144906B4 (de) 2001-09-12 2013-11-28 Novartis Vaccines And Diagnostics Gmbh Verfahren zur großtechnischen Herstellung von Impfstoffen
JP5788303B2 (ja) * 2011-11-30 2015-09-30 積水メディカル株式会社 ＩｇＧ抗体を含有する動物腹水のスクリーニング方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2534529B2 (ja) * 1986-07-24 1996-09-18 ブリティシュ・テレコミュニケ−ションズ・パブリック・リミテッド・カンパニ 放射発生器

Also Published As

Publication number Publication date
DE69024392D1 (de) 1996-02-08
CA2012676A1 (en) 1990-09-29
ATE132160T1 (de) 1996-01-15
IE901136L (en) 1990-09-29
DK78990D0 (da) 1990-03-28
EP0389925A1 (en) 1990-10-03
EP0389925B1 (en) 1995-12-27
DE69024392T2 (de) 1996-07-25
JPH03175991A (ja) 1991-07-31
DK78990A (da) 1990-09-30
IE71949B1 (en) 1997-03-12

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