ES2082104T3 - Hidrogenacion asimetrica. - Google Patents

Hidrogenacion asimetrica.

Info

Publication number
ES2082104T3
ES2082104T3 ES91121704T ES91121704T ES2082104T3 ES 2082104 T3 ES2082104 T3 ES 2082104T3 ES 91121704 T ES91121704 T ES 91121704T ES 91121704 T ES91121704 T ES 91121704T ES 2082104 T3 ES2082104 T3 ES 2082104T3
Authority
ES
Spain
Prior art keywords
asymmetric hydrogenation
formula
atropisomera
propeno
phosphine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91121704T
Other languages
English (en)
Inventor
Emil Albin Dr Broger
Yvo Dr Crameri
Hans Peter Dr Isenring
Albert Dr Pfiffner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2082104T3 publication Critical patent/ES2082104T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/02—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by hydrogenation
    • C07C5/10—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by hydrogenation of aromatic six-membered rings
    • C07C5/11—Partial hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/20—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part monocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO PARA LA HIDROGENACION ASIMETRICA DE (E)-2 -METILO-3-FENILO-2-PROPENO-1-OL DE LA FORMULA EN LA CUAL R SUB 1, TIENE LA SIGNIFICACION MENCIONADA EN ESTO, A COMBINACIONES DE LA FORMULA COMO CATALIZADOR SIRVE UN COMPLEJO-RH CATIONICO O NEUTRO DE UNA FOSFINA ATROPISOMERA.
ES91121704T 1990-12-21 1991-12-18 Hidrogenacion asimetrica. Expired - Lifetime ES2082104T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH410090 1990-12-21

Publications (1)

Publication Number Publication Date
ES2082104T3 true ES2082104T3 (es) 1996-03-16

Family

ID=4269826

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91121704T Expired - Lifetime ES2082104T3 (es) 1990-12-21 1991-12-18 Hidrogenacion asimetrica.

Country Status (16)

Country Link
EP (1) EP0492401B1 (es)
JP (1) JPH04295440A (es)
KR (1) KR920011975A (es)
AT (1) ATE133403T1 (es)
CA (1) CA2058112A1 (es)
CZ (1) CZ280199B6 (es)
DE (1) DE59107308D1 (es)
DK (1) DK0492401T3 (es)
ES (1) ES2082104T3 (es)
FI (1) FI915962A7 (es)
GR (1) GR3018831T3 (es)
HU (1) HU210521B (es)
IE (1) IE71201B1 (es)
IL (1) IL100431A (es)
MX (1) MX9102682A (es)
TW (1) TW200449B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374727A (en) * 1992-06-19 1994-12-20 Hoffmann-La Roche Inc. Asymmetric hydrogenation of dihydro-pyrido [1,2-a]indoles
IT1276165B1 (it) 1995-11-24 1997-10-27 Caffaro Spa Ind Chim Procedimento per la sintesi enantioselettiva di derivati chirali di s-3-(4'-tert-butil)-fenil-2-metil propilammina, fungicidi sistemici
EP0974590A1 (en) * 1998-07-13 2000-01-26 F. Hoffmann-La Roche Ag Process for the preparation of chiral lactones by asymetrical hydrogenation
US6222039B1 (en) 1998-07-13 2001-04-24 Hoffman-La Roche Inc. Process for the preparation of chiral lactones
DE102004047836A1 (de) * 2004-09-29 2006-03-30 Basf Ag Verfahren zur Herstellung von optisch aktiven 2-Methylalkanolen
JP4763771B2 (ja) * 2005-03-17 2011-08-31 ビーエーエスエフ ソシエタス・ヨーロピア 光学活性３−フェニルプロピオン酸誘導体を生成する方法、およびその誘導体の後続生成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT354187B (de) * 1976-11-22 1979-12-27 Hoffmann La Roche Fungizides mittel
DE3001303A1 (de) * 1980-01-16 1981-07-23 Basf Ag, 6700 Ludwigshafen Optisch aktive phenylpropan-derivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
EP0492401A1 (de) 1992-07-01
GR3018831T3 (en) 1996-04-30
ATE133403T1 (de) 1996-02-15
EP0492401B1 (de) 1996-01-24
FI915962A0 (fi) 1991-12-18
HU210521B (en) 1995-04-28
CS387591A3 (en) 1992-07-15
CA2058112A1 (en) 1992-06-22
HUT59650A (en) 1992-06-29
JPH04295440A (ja) 1992-10-20
IE914509A1 (en) 1992-07-01
TW200449B (es) 1993-02-21
DK0492401T3 (da) 1996-03-04
DE59107308D1 (de) 1996-03-07
FI915962L (fi) 1992-06-22
MX9102682A (es) 1992-06-01
HU914088D0 (en) 1992-03-30
FI915962A7 (fi) 1992-06-22
CZ280199B6 (cs) 1995-11-15
IL100431A (en) 1995-12-31
IE71201B1 (en) 1997-02-12
IL100431A0 (en) 1992-09-06
KR920011975A (ko) 1992-07-25

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