ES2082288T3 - Composiciones terapeuticas para administracion intranasal de ketorolaco. - Google Patents

Composiciones terapeuticas para administracion intranasal de ketorolaco.

Info

Publication number
ES2082288T3
ES2082288T3 ES92112394T ES92112394T ES2082288T3 ES 2082288 T3 ES2082288 T3 ES 2082288T3 ES 92112394 T ES92112394 T ES 92112394T ES 92112394 T ES92112394 T ES 92112394T ES 2082288 T3 ES2082288 T3 ES 2082288T3
Authority
ES
Spain
Prior art keywords
therapeutic compositions
intranasal administration
ketorolaco
pirrolic
racemically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92112394T
Other languages
English (en)
Inventor
Giancarlo Santus
Giuseppe Bottoni
Ettore Bilato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati SA
Original Assignee
Recordati SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11360400&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2082288(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati SA filed Critical Recordati SA
Application granted granted Critical
Publication of ES2082288T3 publication Critical patent/ES2082288T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

NUEVAS COMPOSICIONES TERAPEUTICAS CON ACTIVIDAD ANALGESICA Y ANTI-INFLAMATORIA, DE ADMINISTRACION INTRANASAL QUE CONTIENEN COMO INGREDIENTE ACTIVO UNA CANTIDAD EFECTIVA, DE 0,5 A 40 MG POR DOSIS, DE ACIDO 5-BENZOIL-2,3-DIHIDRO-1H-PIRROLICINA-1CARBOXILICO (KETOROLAC TM) A MODO RACEMICO U OPTICAMENTE ACTIVO O SALES TERAPEUTICAMENTE ACEPTABLES DEL MISMO.
ES92112394T 1991-07-22 1992-07-20 Composiciones terapeuticas para administracion intranasal de ketorolaco. Expired - Lifetime ES2082288T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912024A IT1250691B (it) 1991-07-22 1991-07-22 Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.

Publications (1)

Publication Number Publication Date
ES2082288T3 true ES2082288T3 (es) 1996-03-16

Family

ID=11360400

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92112394T Expired - Lifetime ES2082288T3 (es) 1991-07-22 1992-07-20 Composiciones terapeuticas para administracion intranasal de ketorolaco.

Country Status (9)

Country Link
US (3) US6333044B1 (es)
EP (1) EP0524587B1 (es)
JP (1) JP3586735B2 (es)
AT (1) ATE130758T1 (es)
DE (1) DE69206345T2 (es)
DK (1) DK0524587T3 (es)
ES (1) ES2082288T3 (es)
GR (1) GR3019012T3 (es)
IT (1) IT1250691B (es)

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FR2781156B1 (fr) * 1998-07-20 2001-06-29 Lafon Labor Composition pharmaceutique destinee notamment a la prevention et au traitement des radiomucites et des chimiomucites
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US20050232868A1 (en) * 1999-10-19 2005-10-20 The Procter & Gamble Company Methods of entrapping, inactivating, and removing viral infections by the administration of respiratory tract compositions
AR026073A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
US7977376B2 (en) 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
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US20090035260A1 (en) * 2002-07-29 2009-02-05 Therapicon Srl Enhanced nasal composition of active peptide
US7166641B2 (en) * 2002-10-02 2007-01-23 Yung Shin Pharmaceutical Industrial Co., Ltd. Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same
ES2312844T3 (es) * 2002-12-12 2009-03-01 Nycomed Gmbh Medicamento de combinacion de r, r-formoterol y ciclesonida.
JPWO2004113332A1 (ja) * 2003-06-19 2006-07-27 小野薬品工業株式会社 経鼻製剤
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AU2004271744B2 (en) * 2003-09-16 2010-07-29 Covis Pharma B.V. Use of ciclesonide for the treatment of respiratory diseases
US20050175679A1 (en) * 2004-02-10 2005-08-11 Michael Moshman Controlled release formulations
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CN101980738A (zh) 2008-02-07 2011-02-23 华盛顿大学 圆周气雾设备
US9192571B2 (en) * 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
RU2431469C1 (ru) * 2008-03-03 2011-10-20 Аллерган, Инк. Композиции кеторолака трометамина для лечения или профилактики глазной боли
US7842714B2 (en) 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
JP2011524366A (ja) * 2008-06-13 2011-09-01 ロクスロ・ファーマ・インコーポレイテッド 鼻内投与のためのケトロラクの薬学的処方物
JP2012505223A (ja) 2008-10-07 2012-03-01 エムペックス・ファーマシューティカルズ・インコーポレーテッド 薬物動態の改善のためのエアゾールフルオロキノロン配合物
EP2346509B1 (en) 2008-10-07 2020-05-13 Horizon Orphan LLC Inhalation of levofloxacin for reducing lung inflammation
US8551454B2 (en) * 2009-03-13 2013-10-08 Luitpold Pharmaceuticals, Inc. Device for intranasal administration
US8277781B2 (en) 2009-03-13 2012-10-02 Luitpold Pharmaceuticals, Inc. Device for intranasal administration
RU2563809C2 (ru) 2009-09-04 2015-09-20 Мпекс Фармасьютикалс, Инк. Применение левофлоксацина в форме аэрозоля для лечения муковисцидоза
WO2012024595A2 (en) * 2010-08-20 2012-02-23 University Of Washington Circumferential aerosol device for delivering drugs to olfactory epithelium and brain
CA2828884C (en) 2011-03-03 2021-04-27 Impel Neuropharma, Inc. Nasal drug delivery device
WO2012127497A1 (en) 2011-03-04 2012-09-27 Cadila Healthcare Limited Stable pharmaceutical compositions of ketorolac or salts thereof
JP6645735B2 (ja) 2011-05-09 2020-02-14 インペル ニューロファーマ インコーポレイテッド 鼻薬送達用ノズル
US10537692B2 (en) 2013-04-28 2020-01-21 Impel Neuropharma, Inc. Medical unit dose container
EP3129013A1 (en) * 2014-04-10 2017-02-15 Crowley, Patrick Delivery of non-steroidal antiinflammatory agents to the brain via the nasal tract to treat neurological disorders
IL257845B (en) 2015-09-10 2022-07-01 Impel Neuropharma Inc In-line nasal delivery device
IL256819A (en) * 2017-01-09 2018-02-28 Steadymed Ltd Enhanced stability ketorolac formulations and methods and devices for use with same
US11053037B2 (en) * 2017-10-06 2021-07-06 Hikma Pharmaceuticals Usa Inc. System and method for purging oxygen from medical vials
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WO2019104205A1 (en) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with dip tube
US11278492B2 (en) 2018-01-05 2022-03-22 Impel Neuropharma, Inc. Intranasal delivery of olanzapine by precision olfactory device
BR112020013744A8 (pt) 2018-01-05 2022-10-18 Impel Neuropharma Inc Dispensação intranasal de di-hidroergotamina por dispositivo olfativo de precisão
US11517548B2 (en) 2018-07-19 2022-12-06 Impel Pharmaceuticals Inc. Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease
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BR112021023049A8 (pt) 2019-05-17 2022-10-18 Impel Neuropharma Inc Dispositivo de dispensação nasal de uso único
US20240285594A1 (en) * 2023-02-28 2024-08-29 North Carolina State University Compositions and methods for treating pain in animals

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Also Published As

Publication number Publication date
IT1250691B (it) 1995-04-21
ATE130758T1 (de) 1995-12-15
EP0524587B1 (en) 1995-11-29
US7476689B2 (en) 2009-01-13
ITMI912024A1 (it) 1993-01-22
DE69206345D1 (de) 1996-01-11
US6333044B1 (en) 2001-12-25
DK0524587T3 (da) 1996-04-09
JP3586735B2 (ja) 2004-11-10
DE69206345T2 (de) 1996-04-25
JPH05194215A (ja) 1993-08-03
US20040171666A1 (en) 2004-09-02
US7267827B2 (en) 2007-09-11
US20020077346A1 (en) 2002-06-20
EP0524587A1 (en) 1993-01-27
ITMI912024A0 (it) 1991-07-22
GR3019012T3 (en) 1996-05-31

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