ES2084030T3 - Expresion del fragmento c de la toxina del tetanos - Google Patents

Expresion del fragmento c de la toxina del tetanos

Info

Publication number
ES2084030T3
ES2084030T3 ES90909052T ES90909052T ES2084030T3 ES 2084030 T3 ES2084030 T3 ES 2084030T3 ES 90909052 T ES90909052 T ES 90909052T ES 90909052 T ES90909052 T ES 90909052T ES 2084030 T3 ES2084030 T3 ES 2084030T3
Authority
ES
Spain
Prior art keywords
fragment
expression
tetanus toxin
tetanus
toxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909052T
Other languages
English (en)
Inventor
Neil Fraser Fairweather
Andrew Joseph Makoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Pharma Ltd
Original Assignee
Evans Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evans Medical Ltd filed Critical Evans Medical Ltd
Application granted granted Critical
Publication of ES2084030T3 publication Critical patent/ES2084030T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

UN PROCESO PARA LA PRODUCCION DEL FRAGMENTO C DE LA TOXINA DEL TETANOS.
ES90909052T 1989-06-20 1990-06-20 Expresion del fragmento c de la toxina del tetanos Expired - Lifetime ES2084030T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898914122A GB8914122D0 (en) 1989-06-20 1989-06-20 Polypeptide expression

Publications (1)

Publication Number Publication Date
ES2084030T3 true ES2084030T3 (es) 1996-05-01

Family

ID=10658724

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90909052T Expired - Lifetime ES2084030T3 (es) 1989-06-20 1990-06-20 Expresion del fragmento c de la toxina del tetanos

Country Status (9)

Country Link
US (1) US5443966A (es)
EP (1) EP0478602B1 (es)
JP (1) JP2981286B2 (es)
AT (1) ATE132532T1 (es)
DE (1) DE69024652T2 (es)
DK (1) DK0478602T3 (es)
ES (1) ES2084030T3 (es)
GB (1) GB8914122D0 (es)
WO (1) WO1990015871A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5601826A (en) * 1989-06-30 1997-02-11 The United States Of America As Represented By The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
GB9209118D0 (en) * 1992-04-28 1992-06-10 Sb 120 Amsterdam Bv Vaccine compositions
AU4545393A (en) * 1992-06-30 1994-01-24 United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Peptide which produces protective immunity against tetanus
US6680182B1 (en) 1992-07-31 2004-01-20 Acambis Research Limited Expression of recombinant fusion proteins in attenuated bacteria
GB9401787D0 (en) * 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccine compositions
JP2000501744A (ja) * 1996-01-22 2000-02-15 クリエイティブ バイオモレキゥルズ，インコーポレーテッド モルホゲン類似体およびその製法
US20030185792A1 (en) * 1996-01-22 2003-10-02 Curis, Inc. Morphogen analogs of bone morphogenic proteins
CA2216425C (en) * 1996-03-23 2003-08-12 The Research Foundation For Microbial Diseases Of Osaka University Tetanus toxin functional fragment antigen and tetanus vaccine
US5958469A (en) * 1997-05-14 1999-09-28 Eastman Kodak Company Method for fabricating tools for molding diffractive surfaces on optical lenses
US20100081197A1 (en) * 1997-08-14 2010-04-01 Sylvie Roux In vivo modulation of neuronal transport
US7923216B2 (en) * 1997-08-14 2011-04-12 Institut Pasteur In vivo modulation of neuronal transport
DK1049712T3 (da) * 1997-08-14 2007-05-29 Pasteur Institut Hybrid-tetanus-toxoid-proteiner der retrogradt og transsynaptisk migrerer ind i CNS
HU227893B1 (en) 2000-06-29 2012-05-29 Glaxosmithkline Biolog Sa Vaccine compositions
GB0108364D0 (en) 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
EP1575505A4 (en) * 2002-09-10 2007-01-24 Vical Inc CODON OPTIMIZATION-BASED POLYNUCLEOTIDE VACCINES AGAINST BACILLUS ANTHRACIS INFECTION
CA2530363C (en) * 2003-06-23 2013-05-07 Baxter International Inc. Carrier proteins for vaccines
US20070092449A1 (en) * 2005-04-05 2007-04-26 Rafael Vazquez-Martinez Methods for direct visualization of active synapses
EP1790358A1 (en) * 2005-11-23 2007-05-30 Université de Reims Champagne-Ardennes Protein constructs designed for targeting and lysis of cells
US8945582B2 (en) 2006-09-07 2015-02-03 Glaxosmithkline Biologicals S.A. Vaccine
BRPI0810778A2 (pt) 2007-05-02 2011-09-13 Glaxosmithkline Biolog Sa kit, vacina combinada, e, métodos de diminuição da interferência de vizinhança de crm sobre um antìgeno sensìvel em um esquema de imunização primária de uma vacina, e de diminuição da interferência de vizinhança sobre um antìgeno sensìvel, e, uso de conjugados de sacarìdeo
EP2553102B1 (en) 2010-03-30 2015-12-09 Pfenex Inc. High level expression of recombinant toxin proteins
US8703733B2 (en) 2010-05-14 2014-04-22 The Children's Hospital Of Philadelphia Humanized TTC and methods of use thereof
GB201105981D0 (en) 2011-04-08 2011-05-18 Glaxosmithkline Biolog Sa Novel process
DK2788021T3 (en) 2011-12-09 2017-04-10 Bavarian Nordic As POXVIRUS VECTOR FOR EXPRESSION OF BACTERIAL ANTIGENES CONNECTED TO TETANANOX INFRAGMENT C
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
AP2015008702A0 (en) 2013-03-08 2015-09-30 Crucell Holland Bv Acellular pertussis vaccine
US20170151316A1 (en) 2014-07-02 2017-06-01 Spherium Biomed, S.L. Methods of increasing muscle mass using non-toxic tetanus toxin c fragment (ttc)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355094C3 (de) * 1973-11-03 1979-05-23 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tetanus-Impfstoffs
GB8516442D0 (en) * 1985-06-28 1985-07-31 Wellcome Found Cloned antigen

Also Published As

Publication number Publication date
JPH04506005A (ja) 1992-10-22
GB8914122D0 (en) 1989-08-09
DK0478602T3 (da) 1996-02-05
US5443966A (en) 1995-08-22
DE69024652T2 (de) 1996-05-15
EP0478602A1 (en) 1992-04-08
JP2981286B2 (ja) 1999-11-22
EP0478602B1 (en) 1996-01-03
ATE132532T1 (de) 1996-01-15
WO1990015871A1 (en) 1990-12-27
DE69024652D1 (de) 1996-02-15

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