ES2084594T3 - Derivados de carboestirilo. - Google Patents

Derivados de carboestirilo.

Info

Publication number
ES2084594T3
ES2084594T3 ES89120001T ES89120001T ES2084594T3 ES 2084594 T3 ES2084594 T3 ES 2084594T3 ES 89120001 T ES89120001 T ES 89120001T ES 89120001 T ES89120001 T ES 89120001T ES 2084594 T3 ES2084594 T3 ES 2084594T3
Authority
ES
Spain
Prior art keywords
group
formula
derivatives
atom
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89120001T
Other languages
English (en)
Inventor
Yasuo Oshiro
Seiji Sato
Nobuyuki Kurahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17576714&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2084594(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2084594T3 publication Critical patent/ES2084594T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE PRESENTAN DERIVADOS DEL CARBOSTIRIL Y LAS SALES DEL MISMO QUE SE REPRESENTAN MEDIANTE LA FORMULA (I) EN DONDE R ES UN GRUPO DE LA FORMULA (II) (EN DONDE R1 ES UN GRUPO ALCOXIDO C1 - C3), UN GRUPO DE LA FORMULA (III) (EN DONDE R2 Y R3 SON CADA UNA, AL MISMO TIEMPO, UN ATOMO DE CLORO, UN ATOMO DE BROMO; Y R4 ES UN ATOMO DE HIDROGENO O UN ATOMO DE CLORO), UN GRUPO 2-METIL-3-NITROFENIL, UN GRUPO 3.5-DICLOROFENIL, O UN GRUPO DE LA FORMULA (IV) ((DONDE R9 ES UN ATOMO DE CLORO O UN ATOMO DE BROMO; Y R6 ES UN GRUPO METIL)); EL ENLACE CARBONO-CARBONO ENTRE LAS POSICIONES 3- Y 4- EN EL ESQUELETO DEL CARBOSTIRIL ES UN SIMPLE O DOBLE ENLACE). EL NUEVO DERIVADO DE CARBOSTIRIL Y LAS SALES DEL MISMO REPRESENTADO EN LA FORMULA (I) ES UN AGENTE UTIL PARA EL TRATAMIENTO DE LA ESQUIZOFRENIA
ES89120001T 1988-10-31 1989-10-27 Derivados de carboestirilo. Expired - Lifetime ES2084594T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27695388 1988-10-31

Publications (1)

Publication Number Publication Date
ES2084594T3 true ES2084594T3 (es) 1996-05-16

Family

ID=17576714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89120001T Expired - Lifetime ES2084594T3 (es) 1988-10-31 1989-10-27 Derivados de carboestirilo.

Country Status (10)

Country Link
US (1) US5006528A (es)
EP (1) EP0367141B1 (es)
KR (1) KR0138529B1 (es)
CN (1) CN1028104C (es)
DE (2) DE68925405T2 (es)
DK (1) DK168485B1 (es)
ES (1) ES2084594T3 (es)
HK (1) HK1002706A1 (es)
MX (1) MX9202934A (es)
NL (1) NL300161I2 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7807680B2 (en) 2003-10-23 2010-10-05 Otsuka Pharmaceutical Co., Ltd. Controlled release sterile injectable aripiprazole formulation and method
US9457026B2 (en) 2007-07-31 2016-10-04 Otsuka Pharmaceutical Co., Ltd. Methods for producing aripiprazole suspension and freeze-dried formulation

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* Cited by examiner, † Cited by third party
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DE122004000043I2 (de) 2005-06-16
MX9202934A (es) 1992-06-30
CN1028104C (zh) 1995-04-05
KR900006320A (ko) 1990-05-07
US5006528A (en) 1991-04-09
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DK539789A (da) 1990-05-01
DE122004000043I1 (de) 2005-02-03
CN1042537A (zh) 1990-05-30
EP0367141A2 (en) 1990-05-09
NL300161I1 (nl) 2004-12-01
EP0367141A3 (en) 1991-06-12
EP0367141B1 (en) 1996-01-10
KR0138529B1 (ko) 1998-05-15
DK168485B1 (da) 1994-04-05
HK1002706A1 (en) 1998-09-11
DK539789D0 (da) 1989-10-30
DE68925405T2 (de) 1996-06-27

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