ES2084668T3 - Procedimiento. - Google Patents

Procedimiento.

Info

Publication number
ES2084668T3
ES2084668T3 ES90311979T ES90311979T ES2084668T3 ES 2084668 T3 ES2084668 T3 ES 2084668T3 ES 90311979 T ES90311979 T ES 90311979T ES 90311979 T ES90311979 T ES 90311979T ES 2084668 T3 ES2084668 T3 ES 2084668T3
Authority
ES
Spain
Prior art keywords
fha
superfloating
pertussis
antigenic
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90311979T
Other languages
English (en)
Inventor
Carine Capiau
Pierre Desmons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Biologicals SA filed Critical SmithKline Beecham Biologicals SA
Application granted granted Critical
Publication of ES2084668T3 publication Critical patent/ES2084668T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Semiconductor Lasers (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

LA INVENCION PROPORCIONA UNOS METODOS PERFECCIONADOS PARA LA EXTRACCION Y PURIFICACION DESDE UN CALDO DE FERMENTACION O UN CULTIVO SUPERFLOTANTE DE B. PERTUSSIS DE UNO O DE AMBOS FACTORES ANTIGENICOS PT Y FHA. TAMBIEN SE PROPORCIONAN LOS ANTIGENOS PT Y FHA.
ES90311979T 1989-11-06 1990-11-01 Procedimiento. Expired - Lifetime ES2084668T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43199989A 1989-11-06 1989-11-06

Publications (1)

Publication Number Publication Date
ES2084668T3 true ES2084668T3 (es) 1996-05-16

Family

ID=23714322

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90311979T Expired - Lifetime ES2084668T3 (es) 1989-11-06 1990-11-01 Procedimiento.

Country Status (15)

Country Link
EP (1) EP0427462B1 (es)
JP (1) JP3148895B2 (es)
KR (1) KR0161281B1 (es)
AT (1) ATE134194T1 (es)
AU (1) AU635083B2 (es)
CA (1) CA2029201C (es)
CY (1) CY1934A (es)
DE (1) DE69025375T2 (es)
DK (1) DK0427462T3 (es)
ES (1) ES2084668T3 (es)
GR (1) GR3019725T3 (es)
IE (1) IE71687B1 (es)
NZ (1) NZ235960A (es)
PT (1) PT95789B (es)
ZA (1) ZA908801B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI945483A7 (fi) 1992-05-23 1995-01-20 Smithkline Beecham Biologicals S A Hepatiitti B - pinta-antigeenejä ja muita antigeenejä sisältäviä yhdistelmärokotteita
US6051240A (en) * 1994-04-28 2000-04-18 Takeda Chemical Industries, Ltd. Method of separating protective components of Bordetella pertussis
DE19512346C1 (de) * 1995-04-01 1996-06-13 Behringwerke Ag Verfahren zur Reinigung von Filamenthämagglutinin und Pertussis-Toxin
GB0313916D0 (en) 2003-06-16 2003-07-23 Glaxosmithkline Biolog Sa Vaccine composition
BR112014017898B1 (pt) 2012-02-01 2021-10-13 Glaxosmithkline Biologicals S.A. Processo de fermentação
AP2015008702A0 (en) 2013-03-08 2015-09-30 Crucell Holland Bv Acellular pertussis vaccine
CN112513248A (zh) * 2018-03-20 2021-03-16 圣诺菲·帕斯图尔公司 培育博德特氏菌属菌种的方法
KR102362777B1 (ko) * 2018-03-27 2022-02-15 주식회사 녹십자 친화성 크로마토그래피 공정을 포함하는 백일해균 유래 단백질 수득 방법
JP7283468B2 (ja) * 2018-03-27 2023-05-30 日本精工株式会社 ステアリング装置
EP4106897A4 (en) * 2020-02-19 2023-10-25 Bio-Rad Laboratories, Inc. Method of preparing polymer-filled chromatography resin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500639A (en) 1981-10-15 1985-02-19 Teijin Limited Culturing Bordetella in media containing etherified cyclodextrin
JPS59175439A (ja) 1983-03-23 1984-10-04 Teijin Ltd 繊維状赤血球凝集素の製法
CA1213234A (en) 1983-03-30 1986-10-28 Akihiro Ginnaga Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine
JPS6098988A (ja) 1983-11-01 1985-06-01 Chemo Sero Therapeut Res Inst Ｌｐｆ−ｈａの精製法
CA1237998A (en) 1984-04-14 1988-06-14 Akihiro Ginnaga Method for purification of filamentous hemagglutinin
GB8601279D0 (en) 1986-01-20 1986-02-26 Public Health Lab Service Purification of pertussis antigens
FR2596413B1 (fr) 1986-03-27 1988-06-10 Merieux Inst Nouveaux milieux de culture de bacteries appartenant au genre bordetella, contenant des derives etherifies de polymeres de d-glucose, et leur application

Also Published As

Publication number Publication date
ATE134194T1 (de) 1996-02-15
JP3148895B2 (ja) 2001-03-26
NZ235960A (en) 1993-11-25
IE903969A1 (en) 1991-05-08
AU635083B2 (en) 1993-03-11
DE69025375D1 (de) 1996-03-28
IE71687B1 (en) 1997-02-26
EP0427462B1 (en) 1996-02-14
KR0161281B1 (ko) 1998-12-01
AU6584690A (en) 1991-05-09
HK1004555A1 (en) 1998-11-27
KR910009283A (ko) 1991-06-28
JPH03169893A (ja) 1991-07-23
ZA908801B (en) 1991-11-27
CY1934A (en) 1990-11-01
GR3019725T3 (en) 1996-07-31
DE69025375T2 (de) 1996-08-01
DK0427462T3 (da) 1996-03-11
PT95789B (pt) 1997-12-31
CA2029201C (en) 2002-07-30
CA2029201A1 (en) 1991-05-07
EP0427462A1 (en) 1991-05-15
PT95789A (pt) 1991-09-13

Similar Documents

Publication Publication Date Title
GR1000023B (el) Καρβαμικος φαινυλεστηρ.
IT1147808B (it) Dispositivo per realizzare colture di microorganismi
DK94783A (da) Fremgangsmaade til fremstilling af kvaternaere 6,11-dihydro-dibenzo-(b,e)-thiepin-11-n-alkyl-norscopinethere og mellemprodukter herfor
ES2109254T3 (es) Proteinas antigenas y vacunas que las contienen para la prevencion de cocidiosis.
ES2084668T3 (es) Procedimiento.
DK0515544T3 (da) Steroidsulfataseinhibitorer
DE69009318D1 (de) Vorrichtung zur Extraktion von Antigenen.
ATE73013T1 (de) Absonderungsraum.
DE122011100046I1 (de) In vitro kulturprozess fur verschiedene stadien von gewebeparasiten.
DE3850592D1 (de) Apparat zur Vorbereitung von Briefen.
MX9201563A (es) Dexilosilbenanomicina b y procedimiento para prepararla.
BG35328A3 (en) Method for preparing imidodisulphamidic derivatives
NO933119D0 (no) Dyrkningsbeholdere for cellekulturer
DK1666057T3 (da) Fremgangsmåde til fremstilling af en acellulær vaccine indeholdende Bordetella pertussis antigener
DK371688D0 (da) Apparat til dyrkning af kulturer
DK0491033T3 (da) Isolering og oprensning af lungesurfactant-protein
BG40806A3 (en) Method for preparing n- phenyl carbamates
DK44688A (da) Beta-alkylmelatoniner, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden
DE69112112D1 (de) Methoden zur Kompensation optischer Relaxationstransienten.
IT8721047A0 (it) Dispositivo per culture microbiologiche.
BG36344A3 (bg) Метод за получаване на 4-хинолонови производни
IT7819138A0 (it) Procedimento per la coltura di microrganismi.
NO165723C (no) Fremgangsmaate til fremstilling av isopropylalkohol og tertiaere c4- c5-alkoholer.
BG38338A3 (en) Method for preparing 6 alpha- methylhydrocortisonic derivatives
DE3887030D1 (de) Serumfreier Nährboden.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 427462

Country of ref document: ES