ES2084827T3 - Composiciones de vacuna mejoradas. - Google Patents
Composiciones de vacuna mejoradas.Info
- Publication number
- ES2084827T3 ES2084827T3 ES91915418T ES91915418T ES2084827T3 ES 2084827 T3 ES2084827 T3 ES 2084827T3 ES 91915418 T ES91915418 T ES 91915418T ES 91915418 T ES91915418 T ES 91915418T ES 2084827 T3 ES2084827 T3 ES 2084827T3
- Authority
- ES
- Spain
- Prior art keywords
- vaccine compositions
- improved vaccine
- compositions
- improved
- immunogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 239000012752 auxiliary agent Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
COMPOSICIONES MEJORADAS PARA VACUNAS QUE CONTIENEN UN COMPUESTO ALQUILO DE CADENA LARGA COMO AGENTE INMUNOAUXILIAR JUNTO CON UN CONJUGADO DE PROTEINAS DE POLISACARIDOS BACTERIANAS. LAS COMPOSICIONES DE LA INVENCION SON UTILES PARA ACTIVAR EL SISTEMA INMUNE PARA CONFERIR INMUNIDAD A UN HUESPED CONTRA EL INMUNOGEN DE UNA MANERA PROFILACTICA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58337290A | 1990-09-17 | 1990-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2084827T3 true ES2084827T3 (es) | 1996-05-16 |
Family
ID=24332852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91915418T Expired - Lifetime ES2084827T3 (es) | 1990-09-17 | 1991-09-12 | Composiciones de vacuna mejoradas. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5773007A (es) |
| EP (1) | EP0549617B1 (es) |
| JP (1) | JPH06500772A (es) |
| CN (1) | CN1060408A (es) |
| AT (1) | ATE135918T1 (es) |
| AU (1) | AU8441991A (es) |
| BR (1) | BR9106853A (es) |
| CA (1) | CA2090673A1 (es) |
| CS (1) | CS283991A3 (es) |
| CZ (1) | CZ42993A3 (es) |
| DE (1) | DE69118389T2 (es) |
| DK (1) | DK0549617T3 (es) |
| ES (1) | ES2084827T3 (es) |
| FI (1) | FI931169L (es) |
| GR (1) | GR3020117T3 (es) |
| HR (1) | HRP920874A2 (es) |
| HU (1) | HUT64237A (es) |
| IE (1) | IE913261A1 (es) |
| IL (1) | IL99403A0 (es) |
| IS (1) | IS3753A7 (es) |
| MX (1) | MX9101077A (es) |
| NO (1) | NO930938L (es) |
| NZ (1) | NZ239643A (es) |
| OA (1) | OA09776A (es) |
| SK (1) | SK18693A3 (es) |
| WO (1) | WO1992004915A1 (es) |
| YU (1) | YU153291A (es) |
| ZA (1) | ZA917356B (es) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE1008977A5 (fr) * | 1994-12-27 | 1996-10-01 | Solvay | Adjuvants pour vaccins. |
| US5695768A (en) | 1995-06-07 | 1997-12-09 | Alberta Research Council | Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides |
| US5866132A (en) * | 1995-06-07 | 1999-02-02 | Alberta Research Council | Immunogenic oligosaccharide compositions |
| US6007819A (en) * | 1995-10-17 | 1999-12-28 | Dovetail Technologies, Inc. | Methods of inducing immunity using low molecular weight immune stimulants |
| PL328096A1 (en) * | 1996-02-01 | 1999-01-04 | North American Vaccine | Expression of external membrane (mb3) protein of neisseria meningitidis of b group in yeasts and vaccines |
| US6299881B1 (en) * | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| US6787523B1 (en) * | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
| US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
| US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| CA2316975C (en) | 1997-12-23 | 2009-03-24 | North American Vaccine, Inc. | Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugate vaccines |
| US20050059802A1 (en) * | 1998-04-07 | 2005-03-17 | Neuralab Ltd | Prevention and treatment of amyloidogenic disease |
| US6858211B1 (en) * | 1998-07-20 | 2005-02-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccines against Escherichia coli O157 infection |
| CA2714833A1 (en) * | 1998-07-20 | 2000-02-03 | Edward Konadu (Deceased) | Vaccines against escherichia coli o157 infection |
| US6824997B1 (en) | 1998-09-18 | 2004-11-30 | Binax, Inc. | Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies |
| US9134303B1 (en) | 1998-08-25 | 2015-09-15 | Alere Scarborough, Inc. | ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto |
| US20080096236A1 (en) * | 1998-08-25 | 2008-04-24 | Binax, Inc. | Method for Detecting the Presence of Target Bacteria or a Target Component Carbohydrate Antigen Thereof |
| US6146902A (en) * | 1998-12-29 | 2000-11-14 | Aventis Pasteur, Inc. | Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions |
| JP2002539273A (ja) * | 1999-03-19 | 2002-11-19 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | ワクチン |
| UA81216C2 (en) * | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
| US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
| PT2332581E (pt) * | 2001-01-23 | 2015-10-16 | Sanofi Pasteur Inc | Vacina meningocócica tri- ou tetravalente de conjugados de polissacárido e crm-197 |
| US20030035806A1 (en) * | 2001-05-11 | 2003-02-20 | D'ambra Anello J. | Novel meningitis conjugate vaccine |
| US7534442B2 (en) * | 2001-08-21 | 2009-05-19 | The Brigham And Women's Hospital, Inc. | Immunogenic compositions comprising covalently bound polysaccharides, antigen, and bacterial toxoid |
| MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| MXPA05008156A (es) * | 2003-02-01 | 2005-09-30 | Neuralab Ltd | Inmunizacion activa para generar anticuerpos para beta-a soluble. |
| CA2844154C (en) * | 2003-08-06 | 2016-12-20 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Polysaccharide-protein conjugate vaccines |
| US8048432B2 (en) | 2003-08-06 | 2011-11-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Polysaccharide-protein conjugate vaccines |
| PE20061329A1 (es) | 2004-12-15 | 2006-12-08 | Neuralab Ltd | Anticuerpos ab humanizados para mejorar la cognicion |
| EP2007427A4 (en) * | 2006-04-11 | 2012-04-04 | Yeda Res & Dev | IMPROVED VACCINES WITH MULTIMETER HSP60 PEPTIDE SUPPORTS |
| US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
| US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
| SI2182983T1 (sl) * | 2007-07-27 | 2014-09-30 | Janssen Alzheimer Immunotherapy | Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
| NZ612315A (en) * | 2009-04-14 | 2014-10-31 | Novartis Ag | Compositions for immunising against staphylococcus aureus |
| US8003112B2 (en) * | 2009-04-16 | 2011-08-23 | Howard University | Meningococcal and pneumococcal conjugate vaccine and method of using same |
| CN102481352A (zh) | 2009-06-22 | 2012-05-30 | 惠氏有限责任公司 | 金黄色葡萄球菌抗原的免疫原性组合物 |
| SA114350400B1 (ar) | 2009-06-22 | 2016-05-26 | ويث ال ال سي | تركيبات وطرق لتحضير تركيبات مولدة للمناعة لمقترن بولي سكاريد كبسولي للنمط المصلي 5 و 8 من المكورات العنقودية الذهبية |
| CN104582723A (zh) * | 2012-08-31 | 2015-04-29 | 诺华股份有限公司 | 用于针对金黄色葡萄球菌的免疫的稳定化的蛋白质 |
| CN102839159B (zh) * | 2012-09-07 | 2014-03-19 | 江苏康淮生物科技有限公司 | 一种CoxA16病毒株和人用CoxA16灭活疫苗 |
| CN106606775A (zh) * | 2015-10-27 | 2017-05-03 | 格里菲斯大学 | 脂质体a群链球菌疫苗 |
| TWI770044B (zh) * | 2016-08-05 | 2022-07-11 | 南韓商Sk生物科技股份有限公司 | 多價肺炎球菌多醣-蛋白質共軛物組成物(一) |
| BR112020004509A8 (pt) | 2017-09-07 | 2023-01-31 | Merck Sharp & Dohme | Conjugado polissacarídeo-proteína carreadora, composição imunogênica compreendendo o mesmo e uso do referido conjugado |
| KR20230008923A (ko) | 2018-02-05 | 2023-01-16 | 사노피 파스퇴르 인코포레이티드 | 다가 폐렴구균성 다당류-단백질 접합체 조성물 |
| EP3782642A4 (en) | 2018-04-18 | 2022-04-13 | SK Bioscience Co., Ltd. | CAPSULE POLYSACCHARIDES FROM STREPTOCOCCUS PNEUMONIAE AND CONJUGATES THEREOF |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1138773A (en) * | 1979-04-18 | 1983-01-04 | Connaught Laboratories Limited | Synthetic adjuvants for stimulation of antigenic responses |
| US4258029A (en) * | 1979-04-23 | 1981-03-24 | Connaught Laboratories Limited | Synthetic adjuvants for stimulation of antigenic responses |
| US5019383A (en) * | 1981-01-09 | 1991-05-28 | New York Blood Center, Inc. | Fatty acid carriers for synthetic peptides |
| EP0064366A1 (en) * | 1981-04-29 | 1982-11-10 | Beecham Group Plc | Pharmaceutical compositions |
| US4663160A (en) * | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
| US4761283A (en) * | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| US4695624A (en) * | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| US4639371A (en) * | 1984-10-02 | 1987-01-27 | New York Blood Center, Inc. | Hepatitis B antigenic compositions and vaccines against hepatitis B derived therefrom |
| CA1267087A (en) * | 1985-02-14 | 1990-03-27 | Nicolaas Visser | Synthetic immunogen |
| US4863735A (en) * | 1985-02-19 | 1989-09-05 | Massachusetts Institute Of Technology | Biodegradable polymeric drug delivery system with adjuvant activity |
| FR2581877B1 (fr) * | 1985-05-14 | 1987-12-18 | Louvain Universite Catholique | Conjugue constitue d'une adhesine de paroi de s. mutans, de nature proteique et d'un polysaccharide de s. mutans, sa preparation et son utilisation notamment dans des vaccins anti-caries |
| DK163176C (da) * | 1985-09-27 | 1992-06-22 | Schweiz Serum & Impfinst | Ugiftig konjugatvaccine mod infektioner af pseudomonas aeruginosa- og escherichia coli- bakterier, fremgangsmaade til fremstilling heraf og anvendelse af vaccinen |
| US4727136A (en) * | 1985-10-01 | 1988-02-23 | Canadian Patents And Development Ltd. | Modified meningococcal group B polysaccharide for conjugate vaccine |
| EP0273512B1 (en) * | 1986-12-19 | 1991-02-27 | Duphar International Research B.V | Stabilised adjuvant suspension comprising dimethyl dioctadecyl ammonium bromide |
| NZ223009A (en) * | 1986-12-31 | 1990-06-26 | Nl Rivm Of Thoven | Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens |
| EP0289110A3 (en) * | 1987-02-02 | 1990-01-24 | Swiss Serum and Vaccine Institute Berne | Conjugate malaria vaccine |
| GB8807860D0 (en) * | 1988-04-05 | 1988-05-05 | Connaught Lab | Pertussis vaccine |
| NZ230424A (en) * | 1988-08-25 | 1992-05-26 | Liposome Co Inc | Liposomal composition comprising an externally disposed antigen |
| EP0449958B9 (en) * | 1988-12-19 | 2003-05-28 | American Cyanamid Company | Meningococcal class 1 outer-membrane protein vaccine |
-
1991
- 1991-09-03 NZ NZ239643A patent/NZ239643A/en unknown
- 1991-09-04 IL IL99403A patent/IL99403A0/xx unknown
- 1991-09-12 BR BR919106853A patent/BR9106853A/pt not_active Application Discontinuation
- 1991-09-12 EP EP91915418A patent/EP0549617B1/en not_active Expired - Lifetime
- 1991-09-12 WO PCT/CA1991/000326 patent/WO1992004915A1/en not_active Ceased
- 1991-09-12 JP JP3514301A patent/JPH06500772A/ja active Pending
- 1991-09-12 AU AU84419/91A patent/AU8441991A/en not_active Abandoned
- 1991-09-12 FI FI931169A patent/FI931169L/fi unknown
- 1991-09-12 SK SK18693A patent/SK18693A3/sk unknown
- 1991-09-12 CZ CS93429A patent/CZ42993A3/cs unknown
- 1991-09-12 DE DE69118389T patent/DE69118389T2/de not_active Expired - Lifetime
- 1991-09-12 DK DK91915418.7T patent/DK0549617T3/da active
- 1991-09-12 CA CA002090673A patent/CA2090673A1/en not_active Abandoned
- 1991-09-12 HU HU9300746A patent/HUT64237A/hu unknown
- 1991-09-12 AT AT91915418T patent/ATE135918T1/de not_active IP Right Cessation
- 1991-09-12 ES ES91915418T patent/ES2084827T3/es not_active Expired - Lifetime
- 1991-09-13 MX MX9101077A patent/MX9101077A/es unknown
- 1991-09-16 ZA ZA917356A patent/ZA917356B/xx unknown
- 1991-09-16 IE IE326191A patent/IE913261A1/en unknown
- 1991-09-16 YU YU153291A patent/YU153291A/sh unknown
- 1991-09-16 IS IS3753A patent/IS3753A7/is unknown
- 1991-09-17 CN CN91108999A patent/CN1060408A/zh active Pending
- 1991-09-17 CS CS912839A patent/CS283991A3/cs unknown
-
1992
- 1992-10-02 HR HR920874A patent/HRP920874A2/xx not_active Application Discontinuation
-
1993
- 1993-03-16 NO NO93930938A patent/NO930938L/no unknown
- 1993-03-17 OA OA60350A patent/OA09776A/en unknown
-
1994
- 1994-08-26 US US08/297,359 patent/US5773007A/en not_active Expired - Lifetime
-
1996
- 1996-05-31 GR GR960401493T patent/GR3020117T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ239643A (en) | 1996-05-28 |
| ZA917356B (en) | 1992-09-30 |
| YU153291A (sh) | 1994-06-24 |
| HRP920874A2 (en) | 1996-04-30 |
| HUT64237A (en) | 1993-12-28 |
| FI931169A7 (fi) | 1993-04-22 |
| CN1060408A (zh) | 1992-04-22 |
| FI931169A0 (fi) | 1993-03-16 |
| AU8441991A (en) | 1992-04-15 |
| JPH06500772A (ja) | 1994-01-27 |
| DE69118389D1 (de) | 1996-05-02 |
| CZ42993A3 (en) | 1994-04-13 |
| IL99403A0 (en) | 1992-08-18 |
| NO930938D0 (no) | 1993-03-16 |
| IE913261A1 (en) | 1992-02-25 |
| SK18693A3 (en) | 1993-08-11 |
| CS283991A3 (en) | 1992-04-15 |
| EP0549617A1 (en) | 1993-07-07 |
| WO1992004915A1 (en) | 1992-04-02 |
| US5773007A (en) | 1998-06-30 |
| GR3020117T3 (en) | 1996-08-31 |
| EP0549617B1 (en) | 1996-03-27 |
| HU9300746D0 (en) | 1993-06-28 |
| OA09776A (en) | 1993-11-30 |
| NO930938L (no) | 1993-03-16 |
| CA2090673A1 (en) | 1992-03-18 |
| FI931169L (fi) | 1993-04-22 |
| DE69118389T2 (de) | 1996-08-29 |
| DK0549617T3 (da) | 1996-04-22 |
| MX9101077A (es) | 1992-05-04 |
| IS3753A7 (is) | 1992-03-18 |
| BR9106853A (pt) | 1993-08-17 |
| ATE135918T1 (de) | 1996-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9101077A (es) | Composicion para vacuna que comprende un conjugado de proteina-polisacarido bacteriano y un adyuvante de alquilo de cadena larga | |
| ES2192582T3 (es) | Composicion de vaccineo, conteniendo quitina, parcialmente deacetilado. | |
| BR9912410A (pt) | Vacina para imunização de aves, e, processos para imunizar uma ave e para preparar uma vacina para imunizar uma ave | |
| ES2121820T3 (es) | Vacuna de conjugados de polisacaridos de neumococos. | |
| ES2140076T3 (es) | Vacunas que contienen una saponina y un esterol. | |
| ES2154263T3 (es) | Vacuna a base de conjugados de o-polisacarido-proteina de escherichia coli. | |
| ES2098029T3 (es) | Vacunas de hepatitis que contienen monofosforil lipido a 3-o-desacilado. | |
| AR023535A1 (es) | Nuevas composiciones. | |
| ES2124701T3 (es) | Composiciones de vacunas. | |
| AR114627A1 (es) | Composición inmunogénica | |
| HUP9701586A2 (hu) | Javított inaktivált vakcinák | |
| ES2058176T3 (es) | Un procedimiento para preparar un derivado peptidico. | |
| ES2054732T3 (es) | Un procedimiento para preparar un derivado peptidico. | |
| ES2043901T3 (es) | Adyuvante para la terapia inmunologica del cancer. | |
| ES2136064T3 (es) | Vacunas de toxoide de pasteurella multocida. | |
| ES2166763T3 (es) | Inmunizacion parenteral contra rotavirus. | |
| MX9301736A (es) | Vacuna de bacterina-toxoide de pasteurella haemolytica tipo a-1. | |
| PL341541A1 (en) | Isolated strains of staphyloccoccus aureus and vaccines prepared of them | |
| ES2059605T3 (es) | Vacuna toxoide de la tosferina. | |
| EP0339040A4 (en) | Swine dysentery vaccine. | |
| ES2102836T3 (es) | El empleo de vacunas antihelminticas en el control de la enfermedad parasitaria asociada con la perdida de la inmunidad natural. | |
| DE69130953D1 (de) | Immunverstärkung von impfstoffen, besonders von impfstoffen gegen schweinepleuropneumonie | |
| MX9704824A (es) | Adyuvantes para vacunas. | |
| RU93005000A (ru) | Композиция вакцин, способ ее получения, способ исключения иммунной реакции | |
| SU1713152A1 (ru) | Адъювант для ящурной вакцины |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 549617 Country of ref document: ES |