ES2121820T3 - Vacuna de conjugados de polisacaridos de neumococos. - Google Patents

Vacuna de conjugados de polisacaridos de neumococos.

Info

Publication number
ES2121820T3
ES2121820T3 ES92300655T ES92300655T ES2121820T3 ES 2121820 T3 ES2121820 T3 ES 2121820T3 ES 92300655 T ES92300655 T ES 92300655T ES 92300655 T ES92300655 T ES 92300655T ES 2121820 T3 ES2121820 T3 ES 2121820T3
Authority
ES
Spain
Prior art keywords
mixed
pro
conjugate vaccine
those
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92300655T
Other languages
English (en)
Other versions
ES2121820T5 (es
Inventor
Peter J Kniskern
Charlotte C Ip
Arpi Hagopian
John P Hennessey Jr
William J Miller
Dennis J Kubek
Pamela D Burke
Stephen Marburg
Richard L Tolman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27094961&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2121820(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of ES2121820T3 publication Critical patent/ES2121820T3/es
Publication of ES2121820T5 publication Critical patent/ES2121820T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)

Abstract

UNA NUEVA VACUNA CONJUGADA QUE CONTIENE UN POLISACARIDO CAPSULAR, MUY PURIFICADO, PARCIALMENTE HIDROLIZADO (PS) DE LA BACTERIA DEL STREPTOCOCCUS PNEUMONIAE (PNEUMOCOCCI, PN) UNIDA A UNA PROTEINA PORTADORA INMUNOGENICA, SE PRODUCE MEDIANTE UN NUEVO PROCESO. EL CONJUGADO ES UTIL PARA LA PREVENCION DE INFECCIONES NEUMOCOCALES. LAS VACUNAS CONTIENEN UNA MEZCLA DE UNO A DIEZ CONJUGADOS (PN-PS-PRO) DE LA PROTEINA POLISACARIDAINMUNOGENICA NEUMONOCOCAL DIFERENTES QUE INDUCEN RESPUESTAS INMUNES RECEPTORAS MUY PROTECTORAS CONTRA LOS PATOGENOS COGNADOS DE LOS QUE SE DERIVAN LOS COMPONENTES POLISACARIDOS. LOS NIÑOS PEQUEÑOS Y LOS MENORES DE DOS AÑOS, NORMALMENTE INCAPACES DE PRODUCIR UNA RESPUESTA INMUNE PROTECTORA AL PN-PS POR SI SOLOS, PRESENTAN RESPUESTAS INMUNES PROTECTORAS TRAS LA VACUNACION CON ESTOS CONJUGADOS DE PN-PS-PRO.
ES92300655T 1991-01-28 1992-01-27 Vacuna conjugada de polisacarido neumococico. Expired - Lifetime ES2121820T5 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US64657091A 1991-01-28 1991-01-28
US646570 1991-01-28
US80794291A 1991-12-19 1991-12-19
US807942 1991-12-19

Publications (2)

Publication Number Publication Date
ES2121820T3 true ES2121820T3 (es) 1998-12-16
ES2121820T5 ES2121820T5 (es) 2010-05-28

Family

ID=27094961

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92300655T Expired - Lifetime ES2121820T5 (es) 1991-01-28 1992-01-27 Vacuna conjugada de polisacarido neumococico.

Country Status (23)

Country Link
US (1) US5623057A (es)
EP (1) EP0497525B2 (es)
JP (1) JPH0794472B2 (es)
KR (1) KR100243958B1 (es)
CN (1) CN1080124C (es)
AT (1) ATE169825T1 (es)
AU (1) AU651656B2 (es)
CA (1) CA2059692C (es)
CZ (1) CZ283284B6 (es)
DE (1) DE69226668T3 (es)
DK (1) DK0497525T4 (es)
ES (1) ES2121820T5 (es)
FI (1) FI107370B (es)
HU (1) HU216101B (es)
IE (1) IE920244A1 (es)
IL (5) IL119961A (es)
LV (1) LV12309B (es)
MX (1) MX9200328A (es)
NO (1) NO304117B1 (es)
NZ (1) NZ241367A (es)
SI (1) SI9210081B (es)
SK (1) SK280659B6 (es)
YU (1) YU49068B (es)

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