ES2085386T3 - Procedimiento para la preparacion de tacs cristalino. - Google Patents

Procedimiento para la preparacion de tacs cristalino.

Info

Publication number
ES2085386T3
ES2085386T3 ES91113868T ES91113868T ES2085386T3 ES 2085386 T3 ES2085386 T3 ES 2085386T3 ES 91113868 T ES91113868 T ES 91113868T ES 91113868 T ES91113868 T ES 91113868T ES 2085386 T3 ES2085386 T3 ES 2085386T3
Authority
ES
Spain
Prior art keywords
tacs
crystalline
procedure
preparation
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91113868T
Other languages
English (en)
Inventor
Reinhard Trodel
Manfred Dr Wieduwilt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2085386T3 publication Critical patent/ES2085386T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Manufacture And Refinement Of Metals (AREA)

Abstract

METODO PARA LA ELABORACION DE TACS CRISTALINO MEDIANTE LA TRANSFORMACION DE 7-ACS Y MMTS EN PRESENCIA DE UNA BASE Y LA PRECIPITACION AÑADIDA MEDIANTE ADITAMENTOS DE UNA SOLUCION DE TACS A UNA CANTIDAD DE UN ACIDO QUE PUEDE CONTENER UN PRECIPITANTE AUXILIAR Y POSTERIORMENTE, LA COMPLEMENTACION DE LA PRECIPITACION POR MEDIO DE OTROS ADITAMENTOS DE ACIDO O POR MEDIO DE OTROS ADITAMENTOS DE LA SOLUCION TACS Y ACIDOS.
ES91113868T 1990-08-23 1991-08-19 Procedimiento para la preparacion de tacs cristalino. Expired - Lifetime ES2085386T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4026630A DE4026630A1 (de) 1990-08-23 1990-08-23 Verfahren zur herstellung von kristalliner tacs

Publications (1)

Publication Number Publication Date
ES2085386T3 true ES2085386T3 (es) 1996-06-01

Family

ID=6412731

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91113868T Expired - Lifetime ES2085386T3 (es) 1990-08-23 1991-08-19 Procedimiento para la preparacion de tacs cristalino.

Country Status (13)

Country Link
US (1) US5521308A (es)
EP (1) EP0474013B1 (es)
JP (1) JP2594720B2 (es)
KR (1) KR100210325B1 (es)
AT (1) ATE134634T1 (es)
CY (1) CY2031A (es)
DE (2) DE4026630A1 (es)
DK (1) DK0474013T3 (es)
ES (1) ES2085386T3 (es)
FI (1) FI96208C (es)
HU (1) HU214324B (es)
IL (1) IL99263A (es)
SG (1) SG48093A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003031451A1 (en) * 2001-10-06 2003-04-17 Ckd Bio Corp. Method for crystallization of 7-aminocephalosporanic acid
JP4046708B2 (ja) * 2004-06-04 2008-02-13 明治製菓株式会社 ３−アルケニルセフェム化合物の製造方法
CA2757497C (en) 2009-04-01 2018-04-17 Sentreheart, Inc. Tissue ligation devices and controls therefor
CN104997574B (zh) 2010-04-13 2017-06-06 森特里心脏股份有限公司 用于向心脏介入和置放装置的方法和装置
US9498206B2 (en) 2011-06-08 2016-11-22 Sentreheart, Inc. Tissue ligation devices and tensioning devices therefor
CN106337075A (zh) * 2016-08-25 2017-01-18 艾美科健（中国）生物医药有限公司 一种酶法合成头孢地嗪钠的工艺
CN108676015A (zh) * 2018-06-29 2018-10-19 苏州中联化学制药有限公司 一种头孢地嗪酸的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55139387A (en) * 1979-04-19 1980-10-31 Yamanouchi Pharmaceut Co Ltd Novel synthetic method of 7-amino-3-heterocyclic thiomethyl-delta3-carboxylic acids
DE3542644A1 (de) * 1985-12-03 1987-06-04 Hoechst Ag Verfahren zur herstellung von cefodizim
DE3911322A1 (de) * 1989-04-07 1990-10-11 Hoechst Ag Verfahren zur herstellung von cefodizim-dinatrium

Also Published As

Publication number Publication date
HU912767D0 (en) 1992-01-28
KR100210325B1 (ko) 1999-07-15
US5521308A (en) 1996-05-28
FI96208B (fi) 1996-02-15
JP2594720B2 (ja) 1997-03-26
HU214324B (hu) 1998-03-02
KR920004399A (ko) 1992-03-27
IL99263A (en) 1996-05-14
FI96208C (fi) 1996-05-27
DE59107451D1 (de) 1996-04-04
JPH04230689A (ja) 1992-08-19
SG48093A1 (en) 1998-04-17
EP0474013A1 (de) 1992-03-11
ATE134634T1 (de) 1996-03-15
HUT59688A (en) 1992-06-29
EP0474013B1 (de) 1996-02-28
CY2031A (en) 1998-02-20
DE4026630A1 (de) 1992-02-27
DK0474013T3 (da) 1996-07-15
IL99263A0 (en) 1992-07-15
FI913951A7 (fi) 1992-02-24
FI913951A0 (fi) 1991-08-21

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