ES2087111T5 - Vacuna sintetica para la induccion especifica de linfocitos t citotoxicos. - Google Patents
Vacuna sintetica para la induccion especifica de linfocitos t citotoxicos.Info
- Publication number
- ES2087111T5 ES2087111T5 ES90121189T ES90121189T ES2087111T5 ES 2087111 T5 ES2087111 T5 ES 2087111T5 ES 90121189 T ES90121189 T ES 90121189T ES 90121189 T ES90121189 T ES 90121189T ES 2087111 T5 ES2087111 T5 ES 2087111T5
- Authority
- ES
- Spain
- Prior art keywords
- lymphocytes
- cytotoxic
- specific induction
- synthetic vaccine
- killer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 title 1
- 230000006698 induction Effects 0.000 title 1
- 229940126577 synthetic vaccine Drugs 0.000 title 1
- 210000001239 CD8-positive, alpha-beta cytotoxic T lymphocyte Anatomy 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 244000045947 parasite Species 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 238000004873 anchoring Methods 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
UNA VACUNA SINTETICA PARA LA INDUCCION ESPECIFICA DE T-LINFOCITOS DE CITOTOXICOS CONSTA DE UN CONJUGADO DE, AL MENOS, UNA COMPOSICION DE INDUCIDO DE MEMBRANA Y DE, AL MENOS, DE UNA PROTEINA QUE CONTIENE UN MATADOR-T-DE CELULAS PITOP DE UN VIRUS, BACTERIA, DE UN PARASITO O DE UN TUMORANTIGEN O, AL MENOS, DE UNA SECUENCIA PARCIAL DE UN VIRUS QUE CONTIENE UN MATADOR-T-DE CELULAS PITOP DE UNA BACTERIA, PARASITO, PROTEINA O DE UN TUMORANTIGEN.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3937412A DE3937412A1 (de) | 1989-11-10 | 1989-11-10 | Synthetische vakzine zur spezifischen induktion zytotoxischer t-lymphozyten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2087111T3 ES2087111T3 (es) | 1996-07-16 |
| ES2087111T5 true ES2087111T5 (es) | 2001-06-16 |
Family
ID=6393249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90121189T Expired - Lifetime ES2087111T5 (es) | 1989-11-10 | 1990-11-06 | Vacuna sintetica para la induccion especifica de linfocitos t citotoxicos. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0431327B2 (es) |
| JP (1) | JP3057748B2 (es) |
| AT (1) | ATE137118T1 (es) |
| DE (2) | DE3937412A1 (es) |
| DK (1) | DK0431327T4 (es) |
| ES (1) | ES2087111T5 (es) |
| GR (1) | GR3019859T3 (es) |
| IE (1) | IE74899B1 (es) |
| PT (1) | PT95824B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6607727B1 (en) | 1991-08-26 | 2003-08-19 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus |
| US6419931B1 (en) | 1991-08-26 | 2002-07-16 | Epimmune Inc. | Compositions and methods for eliciting CTL immunity |
| US5780036A (en) * | 1991-08-26 | 1998-07-14 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus |
| US6322789B1 (en) | 1991-08-26 | 2001-11-27 | Epimmune, Inc. | HLA-restricted hepatitis B virus CTL epitopes |
| CA2081952A1 (en) * | 1991-11-08 | 1993-05-09 | John J. Donnelly | Recombinant dna sequences and plasmids for cellular immunity vaccines from bacterial toxin-antigen conjugates, and methods of their use |
| EP0547681A2 (en) * | 1991-12-18 | 1993-06-23 | Merck & Co. Inc. | Synthetic peptides comprising a cyclic HIV principal neutralizing determinant and a lipopeptide |
| US6235288B1 (en) | 1992-08-26 | 2001-05-22 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus |
| NZ333562A (en) | 1996-06-25 | 2001-04-27 | Stichting Inst Voor Dierhouder | Vaccine comprising antigens bound by thioester or disulphide bonds to fatty acid carriers such palmitic acid, antigens bound in reversible and labile way |
| US6977074B2 (en) | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
| US6861234B1 (en) | 2000-04-28 | 2005-03-01 | Mannkind Corporation | Method of epitope discovery |
| CN101024842A (zh) | 2001-11-07 | 2007-08-29 | 曼康公司 | 编码靶相关抗原表位的表达载体及其设计方法 |
| EA031379B1 (ru) * | 2010-03-23 | 2018-12-28 | Новартис Аг | Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний |
| NL2007536C2 (en) * | 2011-10-05 | 2013-04-08 | Academisch Ziekenhuis Leiden Lumc | Adjuvant compound. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2401173A1 (fr) * | 1977-06-27 | 1979-03-23 | Roussel Uclaf | Nouveaux steroides, leur procede de preparation et leur application dans la synthese de steroides marques au tritium |
| DE3683688D1 (de) * | 1985-04-19 | 1992-03-12 | Wistar Inst | Impfstoff fuer die erzeugung einer gegen ein virus schuetzenden immunogenen t-zellen-antwort. |
| DE3546150A1 (de) * | 1985-06-24 | 1987-01-22 | Hoechst Ag | Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung |
| DE3813821A1 (de) * | 1988-04-22 | 1989-11-02 | Hoechst Ag | Synthetische vakzine gegen die maul- und klauenseuche und verfahren zu deren herstellung |
| WO1989002277A2 (en) * | 1987-08-28 | 1989-03-23 | Board Of Regents, The University Of Texas System | Prophylaxis and therapy of acquired immunodeficiency syndrome |
| AU4030989A (en) * | 1988-02-12 | 1989-09-06 | Regents Of The University Of California, The | Use of synthetic peptides to generate and manipulate cellular immunity |
-
1989
- 1989-11-10 DE DE3937412A patent/DE3937412A1/de not_active Withdrawn
-
1990
- 1990-11-06 DK DK90121189T patent/DK0431327T4/da active
- 1990-11-06 EP EP90121189A patent/EP0431327B2/de not_active Expired - Lifetime
- 1990-11-06 AT AT90121189T patent/ATE137118T1/de not_active IP Right Cessation
- 1990-11-06 DE DE59010300T patent/DE59010300D1/de not_active Expired - Fee Related
- 1990-11-06 ES ES90121189T patent/ES2087111T5/es not_active Expired - Lifetime
- 1990-11-08 PT PT95824A patent/PT95824B/pt not_active IP Right Cessation
- 1990-11-09 JP JP2302820A patent/JP3057748B2/ja not_active Expired - Fee Related
- 1990-11-09 IE IE405190A patent/IE74899B1/en not_active IP Right Cessation
-
1996
- 1996-05-07 GR GR960401244T patent/GR3019859T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0431327B2 (de) | 2001-04-04 |
| PT95824A (pt) | 1991-09-13 |
| ATE137118T1 (de) | 1996-05-15 |
| ES2087111T3 (es) | 1996-07-16 |
| IE904051A1 (en) | 1991-05-22 |
| EP0431327A1 (de) | 1991-06-12 |
| JP3057748B2 (ja) | 2000-07-04 |
| DE59010300D1 (de) | 1996-05-30 |
| JPH0454131A (ja) | 1992-02-21 |
| DK0431327T4 (da) | 2001-06-18 |
| IE74899B1 (en) | 1997-08-13 |
| DE3937412A1 (de) | 1991-05-16 |
| EP0431327B1 (de) | 1996-04-24 |
| DK0431327T3 (da) | 1996-08-12 |
| GR3019859T3 (en) | 1996-08-31 |
| PT95824B (pt) | 2001-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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