ES2088877T3 - Procedimiento de preparacion del 3-pirrolidinol. - Google Patents
Procedimiento de preparacion del 3-pirrolidinol.Info
- Publication number
- ES2088877T3 ES2088877T3 ES89111150T ES89111150T ES2088877T3 ES 2088877 T3 ES2088877 T3 ES 2088877T3 ES 89111150 T ES89111150 T ES 89111150T ES 89111150 T ES89111150 T ES 89111150T ES 2088877 T3 ES2088877 T3 ES 2088877T3
- Authority
- ES
- Spain
- Prior art keywords
- pirrolidinol
- preparation procedure
- formula
- hydroxybutyronitrile
- chlorine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Abstract
PROCESO PARA PREPARAR 3 - PIRROLIDINOL DE FORMULA(II). O UNA SAL SUYA, QUE COMPRENDE REDUCIR 4 - CLORO - 3 HIDROXIBUTIRONITRILO DE FORMULA(I), PARA CONVERTIRLO EN EL CITADO 3 - PIRROLIDINOL. DE ACUERDO CON LA PRESENTE INVENCION EL 3 PIRROLIDINOL ES PARTICULAR 3 - PIRROLIDINOL OPTICAMENTE ACTIVO PUEDE SER PREPARADO DE FORMA ECONOMICA Y EFICIENTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15371888 | 1988-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2088877T3 true ES2088877T3 (es) | 1996-10-01 |
Family
ID=15568585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89111150T Expired - Lifetime ES2088877T3 (es) | 1988-06-22 | 1989-06-20 | Procedimiento de preparacion del 3-pirrolidinol. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4910320A (es) |
| EP (1) | EP0347818B1 (es) |
| JP (1) | JPH0285249A (es) |
| KR (1) | KR0133286B1 (es) |
| CA (1) | CA1334758C (es) |
| DE (1) | DE68923912T2 (es) |
| ES (1) | ES2088877T3 (es) |
| IE (1) | IE62338B1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2735326B2 (ja) * | 1989-12-02 | 1998-04-02 | 鐘淵化学工業株式会社 | 3‐ピロリジノールの製造法 |
| JPH0776209B2 (ja) * | 1990-04-11 | 1995-08-16 | 高砂香料工業株式会社 | 光学活性3―ヒドロキシピロリジン誘導体の製造方法 |
| US5290948A (en) * | 1990-09-17 | 1994-03-01 | Mcneilab, Inc. | Process for producing polyhydroxylated piperidines and pyrrolidines and compounds thereof |
| DE4425071C2 (de) | 1994-07-15 | 1996-08-29 | Degussa | Verfahren zur Herstellung optisch aktiver Pyrrolidine mit hoher Enantiomerenreinheit |
| KR100461569B1 (ko) * | 2002-05-20 | 2004-12-14 | 삼성정밀화학 주식회사 | 광학적으로 순수한 3-히드록시-피롤리딘의 제조방법 |
| KR100939347B1 (ko) * | 2005-07-20 | 2010-01-29 | (주)카이로드 | 광학적으로 순수한 (s)-3-히드록시 피롤리딘의 제조방법 |
| KR100743617B1 (ko) * | 2005-08-25 | 2007-07-27 | 주식회사 알에스텍 | 고광학순도를 갖는 키랄 3-히드록시 피롤리딘 및 그유도체를 제조하는 방법 |
| WO2007024113A1 (en) * | 2005-08-25 | 2007-03-01 | Rstech Corporation | Process for the preparation of chiral 3-hydroxy pyrrolidine compound and derivatives thereof having high optical purity |
| JP5450387B2 (ja) * | 2008-04-02 | 2014-03-26 | 株式会社カネカ | (s)−3−(1−シアノ−1,1−ジフェニルメチル)−ピロリジンの製造法 |
| CN102249971A (zh) * | 2011-08-25 | 2011-11-23 | 成都理工大学 | 1-n-boc-3-羟基吡咯烷的合成工艺方法 |
| EP4382529A1 (en) | 2022-12-07 | 2024-06-12 | Bayer Consumer Care AG | A process for preparing pure (3s)-pyrrolidin-3-ol and pure (3s)-pyrrolidin-3-ol hydrochloride |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE855561C (de) * | 1941-09-27 | 1952-11-13 | Basf Ag | Verfahren zur Herstellung cyclischer Imine bzw. ihrer Salze |
| US3577415A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-substituted phenoxypyrrolidines |
| US3542807A (en) * | 1969-04-14 | 1970-11-24 | Robins Co Inc A H | 1-(omega-benzoylalkyl)-3-substituted pyrrolidines |
| IL83663A0 (en) * | 1986-10-27 | 1988-01-31 | Robins Co Inc A H | Preparation of 3-pyrrolidinols |
-
1989
- 1989-06-15 IE IE195289A patent/IE62338B1/en not_active IP Right Cessation
- 1989-06-16 CA CA000603118A patent/CA1334758C/en not_active Expired - Fee Related
- 1989-06-20 EP EP89111150A patent/EP0347818B1/en not_active Expired - Lifetime
- 1989-06-20 DE DE68923912T patent/DE68923912T2/de not_active Expired - Lifetime
- 1989-06-20 JP JP1157253A patent/JPH0285249A/ja active Pending
- 1989-06-20 ES ES89111150T patent/ES2088877T3/es not_active Expired - Lifetime
- 1989-06-21 KR KR1019890008554A patent/KR0133286B1/ko not_active Expired - Fee Related
- 1989-06-21 US US07/369,164 patent/US4910320A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE68923912D1 (de) | 1995-09-28 |
| JPH0285249A (ja) | 1990-03-26 |
| DE68923912T2 (de) | 1996-01-11 |
| KR0133286B1 (ko) | 1998-04-17 |
| EP0347818A2 (en) | 1989-12-27 |
| CA1334758C (en) | 1995-03-14 |
| KR910000636A (ko) | 1991-01-29 |
| US4910320A (en) | 1990-03-20 |
| EP0347818B1 (en) | 1995-08-23 |
| IE62338B1 (en) | 1995-01-25 |
| IE891952L (en) | 1989-12-22 |
| EP0347818A3 (en) | 1991-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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