ES2089882T3 - Extraccion con disolventes de beta-caroteno. - Google Patents
Extraccion con disolventes de beta-caroteno.Info
- Publication number
- ES2089882T3 ES2089882T3 ES94300849T ES94300849T ES2089882T3 ES 2089882 T3 ES2089882 T3 ES 2089882T3 ES 94300849 T ES94300849 T ES 94300849T ES 94300849 T ES94300849 T ES 94300849T ES 2089882 T3 ES2089882 T3 ES 2089882T3
- Authority
- ES
- Spain
- Prior art keywords
- carotene
- beta
- organic phase
- membrane
- aqueous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 title abstract 5
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 title abstract 5
- 235000013734 beta-carotene Nutrition 0.000 title abstract 5
- 239000011648 beta-carotene Substances 0.000 title abstract 5
- 229960002747 betacarotene Drugs 0.000 title abstract 5
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 title abstract 5
- 238000000605 extraction Methods 0.000 title 1
- 239000002904 solvent Substances 0.000 title 1
- 239000012074 organic phase Substances 0.000 abstract 6
- 239000012528 membrane Substances 0.000 abstract 5
- 239000002028 Biomass Substances 0.000 abstract 3
- 239000008346 aqueous phase Substances 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000001471 micro-filtration Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
- 238000000108 ultra-filtration Methods 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings or cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/60—Edible seaweed
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/40—Colouring or decolouring of foods
- A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
- A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
- A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
- B01D11/0407—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solute
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0415—Solvent extraction of solutions which are liquid in combination with membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0492—Applications, solvents used
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/147—Microfiltration
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/10—Production of fats or fatty oils from raw materials by extracting
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Water Supply & Treatment (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Wood Science & Technology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
EN LA INVENCION SE PRESENTA UN METODO PARA LA EXTRACCION POR SOLVENTE DE (BETA)-CAROTENO DE UNA SUSPENSION DE UNA BIOMASA DE ALGAS ACUOSA SEGUN EL CUAL SE MEZCLA UN ACEITE VEGETAL INMISCIBLE CON AGUA CON UNA SUSPENSION DE UNA BIOMASA ACUOSA, EN DONDE LA BIOMASA CONTIENE EL (BETA)-CAROTENO, PARA FORMAR UNA MEZCLA DE LA FASE ORGANICA Y DE LA SUSPENSION ACUOSA, CON LO QUE EL (BETA)-CAROTENO SE DISUELVE EN LA FASE ORGANICA. DESPUES SE SEPARA LA FASE ORGANICA DE LA FASE ACUOSA HACIENDO PASAR A LA FASE ORGANICA QUE CONTIENE EL (BETA)-CAROTENO DISUELTO A TRAVES DE UNA MEMBRANA SEMIPERMEABLE PARA MICROFILTRAR O ULTRAFILTRAR LA FASE ORGANICA. LA MEMBRANA ES DE UN MATERIAL HIDROFOBICO Y LA FASE ORGANICA SE PASA A TRAVES DE LA MEMBRANA CON UNA CAIDA DE PRESION A TRAVES DE LA MEMBRANA INFERIOR A LA QUE HACE QUE LA FASE ACUOSA PASE A TRAVES DE LA MEMBRANA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA93953 | 1993-02-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2089882T3 true ES2089882T3 (es) | 1996-10-01 |
Family
ID=25582558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94300849T Expired - Lifetime ES2089882T3 (es) | 1993-02-11 | 1994-02-04 | Extraccion con disolventes de beta-caroteno. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5378369A (es) |
| EP (1) | EP0612725B1 (es) |
| JP (1) | JP2672257B2 (es) |
| AT (1) | ATE139997T1 (es) |
| DE (2) | DE69400270T2 (es) |
| DK (1) | DK0612725T3 (es) |
| ES (1) | ES2089882T3 (es) |
| IL (1) | IL108561A (es) |
| ZA (1) | ZA94614B (es) |
| ZW (1) | ZW2694A1 (es) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19531254A1 (de) * | 1995-08-25 | 1997-02-27 | Sueddeutsche Kalkstickstoff | Verfahren zur Extraktion von Carotinfarbstoffen aus festen Naturstoffen |
| HUT75371A (en) * | 1995-10-09 | 1997-05-28 | Motiv Magyar Nemet Kereskedelm | Natural carotene-concentrate of vegetable material and process for producing of that |
| JPH10139659A (ja) * | 1996-09-10 | 1998-05-26 | Freunt Ind Co Ltd | 球形粒子群、その製造方法及びそれを用いた球形粒子製剤 |
| US5910254A (en) * | 1996-12-20 | 1999-06-08 | Eastman Chemical Company | Method for dewatering microalgae with a bubble column |
| AU5695598A (en) * | 1996-12-20 | 1998-07-17 | Eastman Chemical Company | Method for cross flow microfiltration of microalgae in the absence of flocculating agents |
| AU5802398A (en) * | 1996-12-20 | 1998-07-17 | Eastman Chemical Company | Method for deep bed filtration of microalgae |
| US6000551A (en) * | 1996-12-20 | 1999-12-14 | Eastman Chemical Company | Method for rupturing microalgae cells |
| US5776349A (en) * | 1996-12-20 | 1998-07-07 | Eastman Chemical Company | Method for dewatering microalgae with a jameson cell |
| US5951875A (en) * | 1996-12-20 | 1999-09-14 | Eastman Chemical Company | Adsorptive bubble separation methods and systems for dewatering suspensions of microalgae and extracting components therefrom |
| RU2235783C2 (ru) * | 1997-05-02 | 2004-09-10 | ДСМ Ай Пи АССЕТС Б.В. | Выделение кристаллов каротиноида из микробной биомассы |
| US6261460B1 (en) | 1999-03-23 | 2001-07-17 | James A. Benn | Method for removing contaminants from water with the addition of oil droplets |
| GB2358862B (en) | 1999-12-21 | 2004-07-21 | Fermentron Ltd | Processes for Extracting Carotenoids from Biomass Carotenoid Sources |
| PT1239022E (pt) * | 2001-03-09 | 2009-06-05 | Nestle Sa | Óleo contendo um ou mais ácido(s) gordo(s) polinsaturado(s) de cadeia longa provenientes de biomassa, processo de preparação, alimento, composição nutricional, cosmética ou farmacêutica contendo o mesmo |
| ES2195758B1 (es) | 2001-12-31 | 2005-03-01 | Antibioticos, S.A.U. | Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido. |
| EP1361280A1 (en) * | 2002-05-08 | 2003-11-12 | Wageningen University | Process for continuous production and extraction of carotenoids from natural sources |
| AU2006227165B2 (en) | 2005-03-18 | 2011-11-10 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| WO2008042338A2 (en) | 2006-09-28 | 2008-04-10 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| US8298585B2 (en) | 2007-06-06 | 2012-10-30 | Asahi Kasei Chemicals Corporation | Cellulose-based fine core particle and process for producing the same |
| FR2931815B1 (fr) * | 2008-05-30 | 2010-08-20 | Sarl Firmus | Procede ameliore de separation des composes presents dans une phase aqueuse continue d'un effluent a traiter, notamment petrochimique par inversion de phase. |
| IT1392810B1 (it) * | 2009-02-04 | 2012-03-23 | Eni Spa | Procedimento per l'estrazione di lipidi da biomassa algale |
| WO2011004786A1 (ja) * | 2009-07-06 | 2011-01-13 | 積水化学工業株式会社 | 高分子水処理膜 |
| US20110165662A1 (en) * | 2009-07-13 | 2011-07-07 | Inventure Chemical, Inc. | Method for harvesting microalgae suspended in an aqueous solution using a hydrophobic chemical |
| US8617396B2 (en) * | 2010-01-15 | 2013-12-31 | Board Of Regents, The University Of Texas System | Non-dispersive process for insoluble oil recovery from aqueous slurries |
| MX2012007901A (es) * | 2010-01-15 | 2012-08-03 | Univ Texas | Proceso no dispersivo para la recuperacion de aceite insoluble a partir de suspenciones acuosas. |
| US9643127B2 (en) | 2010-01-15 | 2017-05-09 | Board Of Regents Of The University Of Texas System | Simultaneous removal of oil and gases from liquid sources using a hollow fiber membrane |
| US8491792B2 (en) * | 2010-01-15 | 2013-07-23 | Board Of Regents, The University Of Texas System | Non-dispersive process for insoluble oil recovery from aqueous slurries |
| US9688921B2 (en) | 2013-02-26 | 2017-06-27 | Board Of Regents, The University Of Texas System | Oil quality using a microporous hollow fiber membrane |
| US9782726B2 (en) * | 2010-01-15 | 2017-10-10 | Board Of Regents, The University Of Texas System | Non-dispersive process for oil recovery |
| US9149772B2 (en) | 2010-01-15 | 2015-10-06 | Board Of Regents, The University Of Texas Systems | Enhancing flux of a microporous hollow fiber membrane |
| WO2011127127A2 (en) * | 2010-04-06 | 2011-10-13 | Arizona Board Of Regents For And On Behalf Of Arizona State University | Extraction with fractionation of oil and co-products from oleaginous material |
| US8563759B2 (en) | 2010-10-02 | 2013-10-22 | Cal Poly Corporation | Process for extracting lipids from microalgae |
| EP2637516A1 (en) | 2010-11-08 | 2013-09-18 | Feyecon B.V. | Extraction of oil-soluble pigment from micro-organisms |
| CA3102566C (en) * | 2011-06-30 | 2025-08-05 | E. & J. Gallo Winery | NATURAL CRYSTALLINE DYE AND ITS PRODUCTION PROCESS |
| US9399713B1 (en) | 2011-10-12 | 2016-07-26 | Crown Iron Works Company | Asphalt recovery system and process |
| US9039898B2 (en) | 2011-11-15 | 2015-05-26 | Engineering Research Associates, Inc. | Method for separating components in natural oil |
| EP2861330A4 (en) * | 2012-06-14 | 2015-07-15 | Univ Texas | NON-DISPERSIVE OIL RECOVERY FROM LIQUID SOURCES IN THE OIL INDUSTRY |
| US11197843B2 (en) | 2015-08-28 | 2021-12-14 | AlgaHealth (AH) Ltd. | Process for producing fucoxanthin and/or polysaccharides from microalgae |
| CN114207098A (zh) * | 2019-06-14 | 2022-03-18 | 墨尔本大学 | 复杂乳液的剪切诱导的相转化用于从生物质中回收有机成分 |
| CN112869153A (zh) * | 2019-11-29 | 2021-06-01 | 内蒙古伊利实业集团股份有限公司 | 一种制备药食同源植物提取物的方法 |
| GB202211084D0 (en) | 2022-07-29 | 2022-09-14 | Givaudan Sa | Composition |
| FI20245068A1 (en) * | 2023-11-30 | 2025-05-31 | Neste Oyj | Method for desalination, dewatering and de-solubilization of algal biomass |
| WO2025114645A1 (en) | 2023-11-30 | 2025-06-05 | Neste Oyj | A process and system for separating algal hydrophobic products from an algal biomass stream |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2453199A1 (fr) * | 1979-04-06 | 1980-10-31 | Inst Francais Du Petrole | Procede d'extraction selective des colorants contenus dans les algues cyanophycees |
| JPS5656202A (en) * | 1979-10-15 | 1981-05-18 | Asahi Chem Ind Co Ltd | Hollow porous membrane yarn made of polyvinylidene fluoride type resin |
| EP0052777A1 (de) * | 1980-11-20 | 1982-06-02 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Extraktion von beta-Carotin aus Algen |
| US4352736A (en) * | 1980-12-08 | 1982-10-05 | Toyo Boseki Kabushiki Kaisha | Wound flattened hollow fiber assembly having plural spaced core sections |
| JPS61109764A (ja) * | 1984-11-01 | 1986-05-28 | Lion Corp | カロチン含有濃縮物の製造方法 |
| US4680314A (en) * | 1985-08-30 | 1987-07-14 | Microbio Resources, Inc. | Process for producing a naturally-derived carotene/oil composition by direct extraction from algae |
| US4846976A (en) * | 1985-12-06 | 1989-07-11 | Memtec Limited | Treatment of emulsions |
| US4851339A (en) * | 1986-04-01 | 1989-07-25 | Hills Christopher B | Extraction of anti-mutagenic pigments from algae and vegetables |
| US4756835A (en) * | 1986-08-29 | 1988-07-12 | Advanced Polymer Technology, Inc. | Permeable membranes having high flux-density and low fouling-propensity |
| JPS6362504A (ja) * | 1986-09-02 | 1988-03-18 | Mitsubishi Rayon Eng Co Ltd | 有機成分含有水溶液中の有機成分の濃縮方法 |
| DE3934656A1 (de) * | 1989-10-13 | 1991-04-18 | Schering Ag | Verfahren zur herstellung von waessrigen dispersionen |
| EP0685167B1 (en) * | 1990-04-11 | 2000-06-28 | Morinaga Milk Industry Co., Ltd. | Method for producing an oil-in-water-in-oil type emulsion |
| US5157132A (en) * | 1990-05-18 | 1992-10-20 | Carotech Associates | Integrated process for recovery of carotenoids and tocotrienols from oil |
| US5245095A (en) * | 1991-04-12 | 1993-09-14 | Humanetics Corporation | Extraction of carotenoids from natural sources |
| CN1036848C (zh) * | 1991-07-29 | 1997-12-31 | 天津滨海新技术产业集团股份有限公司 | 从盐藻中浸取胡萝卜素的方法 |
| JP3073067B2 (ja) * | 1991-10-04 | 2000-08-07 | キヤノン株式会社 | X線露光用マスク及びその製造方法 |
| US5250182A (en) * | 1992-07-13 | 1993-10-05 | Zenon Environmental Inc. | Membrane-based process for the recovery of lactic acid and glycerol from a "corn thin stillage" stream |
-
1994
- 1994-01-28 ZA ZA94614A patent/ZA94614B/xx unknown
- 1994-02-02 US US08/191,323 patent/US5378369A/en not_active Expired - Fee Related
- 1994-02-04 DE DE69400270T patent/DE69400270T2/de not_active Expired - Fee Related
- 1994-02-04 DK DK94300849.0T patent/DK0612725T3/da active
- 1994-02-04 EP EP94300849A patent/EP0612725B1/en not_active Expired - Lifetime
- 1994-02-04 DE DE0612725T patent/DE612725T1/de active Pending
- 1994-02-04 ES ES94300849T patent/ES2089882T3/es not_active Expired - Lifetime
- 1994-02-04 AT AT94300849T patent/ATE139997T1/de not_active IP Right Cessation
- 1994-02-04 IL IL108561A patent/IL108561A/xx not_active IP Right Cessation
- 1994-02-10 JP JP6051000A patent/JP2672257B2/ja not_active Expired - Fee Related
- 1994-02-11 ZW ZW2694A patent/ZW2694A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0612725T3 (da) | 1996-07-29 |
| DE69400270D1 (de) | 1996-08-08 |
| JPH072761A (ja) | 1995-01-06 |
| ATE139997T1 (de) | 1996-07-15 |
| DE69400270T2 (de) | 1996-12-19 |
| AU662705B2 (en) | 1995-09-07 |
| JP2672257B2 (ja) | 1997-11-05 |
| EP0612725B1 (en) | 1996-07-03 |
| ZW2694A1 (en) | 1994-09-07 |
| IL108561A0 (en) | 1994-05-30 |
| EP0612725A1 (en) | 1994-08-31 |
| ZA94614B (en) | 1994-08-12 |
| US5378369A (en) | 1995-01-03 |
| AU5476494A (en) | 1994-08-18 |
| IL108561A (en) | 1997-11-20 |
| DE612725T1 (de) | 1995-04-06 |
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