ES2091185T3 - Un procedimiento para la preparacion de composiciones bifasicas para dispositivos quirurgicos absorbibles. - Google Patents
Un procedimiento para la preparacion de composiciones bifasicas para dispositivos quirurgicos absorbibles.Info
- Publication number
- ES2091185T3 ES2091185T3 ES88304423T ES88304423T ES2091185T3 ES 2091185 T3 ES2091185 T3 ES 2091185T3 ES 88304423 T ES88304423 T ES 88304423T ES 88304423 T ES88304423 T ES 88304423T ES 2091185 T3 ES2091185 T3 ES 2091185T3
- Authority
- ES
- Spain
- Prior art keywords
- monomer mixture
- lactide
- annealed
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 3
- 239000000178 monomer Substances 0.000 abstract 5
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 abstract 3
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000006116 polymerization reaction Methods 0.000 abstract 1
- 230000000379 polymerizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/041—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Materials For Medical Uses (AREA)
- Polyesters Or Polycarbonates (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
SE PRESENTA UN PROCESO PARA FABRICAR UN DISPOSITIVO QUIRURGICO ABSORVIBLE HECHO A PARTIR DE UN COMPUESTO POLIMERICO DE FASE MULTIPLE DERIVADO DE LACTURO Y GLICORURO. EL DISPOSITIVO TIENE UNA ALTA TEMPERATURA DE DISTORSION, UNA BUENA RESISTENCIA AL ARRASTRAMIENTO EN HUMEDO Y CALIENTE, PERO ADEMAS PIERDE SU FUERZA DE TENSION EN VIVO RAPIDAMENTE. EL COMPUESTO PER SE ES MOLDEABLE A INYECCION, PUEDE SER ESTERILIZADO Y NO ESTA ERIZADO. EL PROCESO DEL INVENTO COMPRENDE LA POLIMERIZACION DE UNA PRIMERA MEZCLA MONOMERA QUE COMPRENDA UNA CANTIDAD PREDOMINANTE DE LACTURO, SEGUIDA POR LA POLIMERIZACION DE UNA SEGUNDA MEZCLA MONOMERA EN PRESENCIA DE LA PRIMERA MEZCLA MONOMERA. DE ESTA MANERA SE FORMA EL POLIMERO Y EL DISPOSITIVO QUIRURGICO SE ESTERILIZA. LA PRIMERA MEZCLA MONOMERA CONTIENE UNA CANTIDAD PREDOMINANTE DE LACTURO Y LA SEGUNDA MEZCLA MONOMERA CONTIENE GLICORURO.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58668684A | 1984-03-06 | 1984-03-06 | |
| US86030286A | 1986-07-17 | 1986-07-17 | |
| US11746687A | 1987-11-05 | 1987-11-05 | |
| EP88304423A EP0342278B1 (en) | 1984-03-06 | 1988-05-16 | A process for making two-phase compositions for absorbable surgical devices |
| US07/562,430 US5124103A (en) | 1984-03-06 | 1990-08-02 | Two phase compositions for absorbable surgical devices |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2091185T3 true ES2091185T3 (es) | 1996-11-01 |
Family
ID=39688787
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88304423T Expired - Lifetime ES2091185T3 (es) | 1984-03-06 | 1988-05-16 | Un procedimiento para la preparacion de composiciones bifasicas para dispositivos quirurgicos absorbibles. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5124103A (es) |
| EP (1) | EP0342278B1 (es) |
| AT (1) | ATE142236T1 (es) |
| DE (1) | DE3855510T2 (es) |
| ES (1) | ES2091185T3 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990001969A1 (en) * | 1988-08-24 | 1990-03-08 | Slepian Marvin J | Biodegradable polymeric endoluminal sealing |
| US5634946A (en) * | 1988-08-24 | 1997-06-03 | Focal, Inc. | Polymeric endoluminal paving process |
| US6387363B1 (en) | 1992-12-31 | 2002-05-14 | United States Surgical Corporation | Biocompatible medical devices |
| US5716413A (en) * | 1995-10-11 | 1998-02-10 | Osteobiologics, Inc. | Moldable, hand-shapable biodegradable implant material |
| US6162537A (en) | 1996-11-12 | 2000-12-19 | Solutia Inc. | Implantable fibers and medical articles |
| US5983366A (en) * | 1997-03-19 | 1999-11-09 | Optimay Corporation | Data processing system having monitoring of software activity |
| EP0949299B1 (en) | 1998-04-06 | 2005-06-15 | Ethicon, Inc. | Two phase thermally deformable biocompatible absorbable polymer matrix for use in medical devices |
| US8372094B2 (en) * | 2004-10-15 | 2013-02-12 | Covidien Lp | Seal element for anastomosis |
| US7794495B2 (en) * | 2006-07-17 | 2010-09-14 | Advanced Cardiovascular Systems, Inc. | Controlled degradation of stents |
Family Cites Families (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2703316A (en) * | 1951-06-05 | 1955-03-01 | Du Pont | Polymers of high melting lactide |
| US2668162A (en) * | 1952-03-20 | 1954-02-02 | Du Pont | Preparation of high molecular weight polyhydroxyacetic ester |
| US2758987A (en) * | 1952-06-05 | 1956-08-14 | Du Pont | Optically active homopolymers containing but one antipodal species of an alpha-monohydroxy monocarboxylic acid |
| NL99836C (es) * | 1954-10-20 | |||
| US3225766A (en) * | 1962-03-26 | 1965-12-28 | Grace W R & Co | Method of making absorbable surgical sutures from poly beta hydroxy acids |
| NL294714A (es) * | 1963-06-28 | |||
| US3875937A (en) * | 1963-10-31 | 1975-04-08 | American Cyanamid Co | Surgical dressings of absorbable polymers |
| US3297033A (en) * | 1963-10-31 | 1967-01-10 | American Cyanamid Co | Surgical sutures |
| US3739773A (en) * | 1963-10-31 | 1973-06-19 | American Cyanamid Co | Polyglycolic acid prosthetic devices |
| US3620218A (en) * | 1963-10-31 | 1971-11-16 | American Cyanamid Co | Cylindrical prosthetic devices of polyglycolic acid |
| US3463158A (en) * | 1963-10-31 | 1969-08-26 | American Cyanamid Co | Polyglycolic acid prosthetic devices |
| US3268487A (en) * | 1963-12-23 | 1966-08-23 | Shell Oil Co | Process for polymerization of lactides |
| US3531561A (en) * | 1965-04-20 | 1970-09-29 | Ethicon Inc | Suture preparation |
| US3442871A (en) * | 1966-05-04 | 1969-05-06 | American Cyanamid Co | Process for polymerizing a glycolide |
| US3422181A (en) * | 1966-05-23 | 1969-01-14 | American Cyanamid Co | Method for heat setting of stretch oriented polyglycolic acid filament |
| US3468853A (en) * | 1966-06-15 | 1969-09-23 | American Cyanamid Co | Process of polymerizing a glycolide |
| US3597449A (en) * | 1967-11-16 | 1971-08-03 | American Cyanamid Co | Stable glycolide and lactide composition |
| US3565869A (en) * | 1968-12-23 | 1971-02-23 | American Cyanamid Co | Extrudable and stretchable polyglycolic acid and process for preparing same |
| US3626948A (en) * | 1968-12-23 | 1971-12-14 | American Cyanamid Co | Absorbable polyglycolic acid suture of enhanced in-vivo strength retention |
| US3772420A (en) * | 1968-12-23 | 1973-11-13 | American Cyanamid Co | Method for improving the in-vivo strength of polyglycolic acid |
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| BE758156R (fr) * | 1970-05-13 | 1971-04-28 | Ethicon Inc | Element de suture absorbable et sa |
| US3797499A (en) * | 1970-05-13 | 1974-03-19 | Ethicon Inc | Polylactide fabric graphs for surgical implantation |
| GB1332505A (en) * | 1970-10-16 | 1973-10-03 | Ethicon Inc | Sutures and other surgical aids |
| US3846382A (en) * | 1971-02-25 | 1974-11-05 | American Cyanamid Co | Sterile medical dusting powder |
| US3781349A (en) * | 1971-02-25 | 1973-12-25 | American Cyanamid Co | Preparation of polyglycolic acid in finely divided form |
| US3878284A (en) * | 1971-08-12 | 1975-04-15 | American Cyanamid Co | Processes for making shaped articles such as filaments or films from solutions of polyglycolic acid |
| US3867190A (en) * | 1971-10-18 | 1975-02-18 | American Cyanamid Co | Reducing capillarity of polyglycolic acid sutures |
| US3736646A (en) * | 1971-10-18 | 1973-06-05 | American Cyanamid Co | Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures |
| US3784585A (en) * | 1971-10-21 | 1974-01-08 | American Cyanamid Co | Water-degradable resins containing recurring,contiguous,polymerized glycolide units and process for preparing same |
| US3839297A (en) * | 1971-11-22 | 1974-10-01 | Ethicon Inc | Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures |
| US3792010A (en) * | 1972-03-27 | 1974-02-12 | Ethicon Inc | Plasticized polyester sutures |
| US3982543A (en) * | 1973-04-24 | 1976-09-28 | American Cyanamid Company | Reducing capillarity of polyglycolic acid sutures |
| US4033938A (en) * | 1974-01-21 | 1977-07-05 | American Cyanamid Company | Polymers of unsymmetrically substituted 1,4-dioxane-2,5-diones |
| GB1414600A (en) * | 1974-02-08 | 1975-11-19 | Ethicon Inc | Plasticised polyester sutures |
| US3902497A (en) * | 1974-03-25 | 1975-09-02 | American Cyanamid Co | Body absorbable sponge and method of making |
| US3896802A (en) * | 1974-04-19 | 1975-07-29 | American Cyanamid Co | Flexible flocked dressing |
| US3937223A (en) * | 1974-04-19 | 1976-02-10 | American Cyanamid Company | Compacted surgical hemostatic felt |
| US4027676A (en) * | 1975-01-07 | 1977-06-07 | Ethicon, Inc. | Coated sutures |
| US4057537A (en) * | 1975-01-28 | 1977-11-08 | Gulf Oil Corporation | Copolymers of L-(-)-lactide and epsilon caprolactone |
| US4045418A (en) * | 1975-01-28 | 1977-08-30 | Gulf Oil Corporation | Copolymers of D,L-lactide and epsilon caprolactone |
| US4014433A (en) * | 1975-05-27 | 1977-03-29 | Ethican, Inc. | Package for moisture sensitive sutures and method for making same |
| US4060089A (en) * | 1975-09-03 | 1977-11-29 | United States Surgical Corporation | Surgical fastening method and device therefor |
| US4201216A (en) * | 1976-12-15 | 1980-05-06 | Ethicon, Inc. | Absorbable coating composition for sutures |
| US4300565A (en) * | 1977-05-23 | 1981-11-17 | American Cyanamid Company | Synthetic polyester surgical articles |
| US4243775A (en) * | 1978-11-13 | 1981-01-06 | American Cyanamid Company | Synthetic polyester surgical articles |
| ZA782039B (en) * | 1977-05-23 | 1979-09-26 | American Cyanamid Co | Surgical articles |
| US4137921A (en) * | 1977-06-24 | 1979-02-06 | Ethicon, Inc. | Addition copolymers of lactide and glycolide and method of preparation |
| US4246904A (en) * | 1979-01-29 | 1981-01-27 | American Cyanamid Company | Surgical suture derived from segmented polyether-ester block copolymers |
| FR2439003A1 (fr) * | 1978-10-20 | 1980-05-16 | Anvar | Nouvelles pieces d'osteosynthese, leur preparation et leur application |
| US4275813A (en) * | 1979-06-04 | 1981-06-30 | United States Surgical Corporation | Coherent surgical staple array |
| US4273920A (en) * | 1979-09-12 | 1981-06-16 | Eli Lilly And Company | Polymerization process and product |
| DE3042052C2 (de) * | 1980-11-07 | 1984-08-09 | MTU Motoren- und Turbinen-Union München GmbH, 8000 München | Vorrichtung zum Spritzgießen von Präzisionsteilen |
| US4490326A (en) * | 1981-07-30 | 1984-12-25 | Ethicon, Inc. | Molding process for polydioxanone polymers |
| FR2510411B1 (fr) * | 1981-07-30 | 1986-09-12 | Ethicon Inc | Appareil chirurgical en polydioxanone reticulee et procede pour sa production |
| US4591630A (en) * | 1981-07-30 | 1986-05-27 | Ethicon, Inc. | Annealed polydioxanone surgical device and method for producing the same |
| US4449531A (en) * | 1981-08-27 | 1984-05-22 | Ethicon, Inc. | Non-metallic, bio-compatible hemostatic clips with interlocking latch means |
| US4402445A (en) * | 1981-10-09 | 1983-09-06 | United States Surgical Corporation | Surgical fastener and means for applying same |
| US4636084A (en) * | 1982-03-16 | 1987-01-13 | Mapro Inc. | Removing volatiles from plastic materials delivered to an extrusion or injection molding machine |
| US4444927A (en) * | 1982-09-13 | 1984-04-24 | Ethicon, Inc. | Sucrose and/or lactose nucleating agents for the crystallization of polydioxanone |
| US4523591A (en) * | 1982-10-22 | 1985-06-18 | Kaplan Donald S | Polymers for injection molding of absorbable surgical devices |
| DE3310676A1 (de) * | 1983-03-24 | 1984-09-27 | Basf Ag, 6700 Ludwigshafen | Verfahren und vorrichtung zum entfernen von fluechtigen anteilen aus polymerenschmelzen oder paste |
| US4591467A (en) * | 1983-07-22 | 1986-05-27 | Mapro Inc. | Method for removing moisture and volatiles from molding particulate plastic material feed |
| US4650488A (en) * | 1984-05-16 | 1987-03-17 | Richards Medical Company | Biodegradable prosthetic device |
| EP0199074B1 (en) * | 1985-03-25 | 1991-03-20 | American Cyanamid Company | Process for manufacturing an annealed prosthetic device |
| US4671280A (en) * | 1985-05-13 | 1987-06-09 | Ethicon, Inc. | Surgical fastening device and method for manufacture |
| US4741337A (en) * | 1985-07-17 | 1988-05-03 | Ethicon, Inc. | Surgical fastener made from glycolide-rich polymer blends |
-
1988
- 1988-05-16 AT AT88304423T patent/ATE142236T1/de not_active IP Right Cessation
- 1988-05-16 EP EP88304423A patent/EP0342278B1/en not_active Expired - Lifetime
- 1988-05-16 ES ES88304423T patent/ES2091185T3/es not_active Expired - Lifetime
- 1988-05-16 DE DE3855510T patent/DE3855510T2/de not_active Expired - Lifetime
-
1990
- 1990-08-02 US US07/562,430 patent/US5124103A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0342278A1 (en) | 1989-11-23 |
| ATE142236T1 (de) | 1996-09-15 |
| US5124103A (en) | 1992-06-23 |
| DE3855510T2 (de) | 1997-02-06 |
| DE3855510D1 (de) | 1996-10-10 |
| EP0342278B1 (en) | 1996-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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