ES2091738T3 - Formulados farmaceuticos que contienen cefaclor. - Google Patents

Formulados farmaceuticos que contienen cefaclor.

Info

Publication number
ES2091738T3
ES2091738T3 ES95304976T ES95304976T ES2091738T3 ES 2091738 T3 ES2091738 T3 ES 2091738T3 ES 95304976 T ES95304976 T ES 95304976T ES 95304976 T ES95304976 T ES 95304976T ES 2091738 T3 ES2091738 T3 ES 2091738T3
Authority
ES
Spain
Prior art keywords
cefaclor
pharmaceutical
formulates
manufacture
species
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95304976T
Other languages
English (en)
Other versions
ES2091738T1 (es
Inventor
Mendizabal Flavia Arce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly SA
Original Assignee
Lilly SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly SA filed Critical Lilly SA
Publication of ES2091738T1 publication Critical patent/ES2091738T1/es
Application granted granted Critical
Publication of ES2091738T3 publication Critical patent/ES2091738T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

FORMULACIONES FARMACEUTICAS DE CEFACLOR, ADECUADAS PARA LA FABRICACION POR COMPRESION DIRECTA DE COMPRIMIDOS DISPERSABLES, QUE CONTIENE EL ANTIBIOTICO CEFACLOR EN UNA CANTIDAD ENTRE UN 35% Y UN 50% EN PESO DEL PESO TOTAL DE LA FORMULACION, JUNTO CON LOS EXCIPIENTES Y COADYUVANTES ADECUADOS SELECCIONADOS ENTRE DESINTEGRADORES, DILUYENTES, LUBRICANTES, ANTIADHERENTES, EDULCORANTES, FRAGANCIAS Y, OPCIONALMENTE, AROMATIZANTES, OPACIFICADORES Y COLORANTES. DICHAS FORMULACIONES SON ADECUADAS PARA LA FABRICACION DE COMPRIMIDOS DISPERSABLES QUE SE DESINTEGRAN EN MENOS DE TRES MINUTOS EN AGUA A UNA TEMPERATURA ENTRE 19 (GRADOS) Y 21 (GRADOS) C, Y SON ADECUADAS PARA EL TRATAMIENTO DE LAS INFECCIONES PROVOCADAS POR AQUELLAS ESPECIES DE BACTERIAS SENSIBLES AL CEFACLOR.
ES95304976T 1994-12-13 1995-07-17 Formulados farmaceuticos que contienen cefaclor. Expired - Lifetime ES2091738T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09402530A ES2079327B1 (es) 1994-12-13 1994-12-13 Formulaciones farmaceuticas de cefaclor.

Publications (2)

Publication Number Publication Date
ES2091738T1 ES2091738T1 (es) 1996-11-16
ES2091738T3 true ES2091738T3 (es) 2001-08-16

Family

ID=8288235

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09402530A Expired - Lifetime ES2079327B1 (es) 1994-12-13 1994-12-13 Formulaciones farmaceuticas de cefaclor.
ES95304976T Expired - Lifetime ES2091738T3 (es) 1994-12-13 1995-07-17 Formulados farmaceuticos que contienen cefaclor.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES09402530A Expired - Lifetime ES2079327B1 (es) 1994-12-13 1994-12-13 Formulaciones farmaceuticas de cefaclor.

Country Status (31)

Country Link
US (1) US5861141A (es)
EP (3) EP1086689A3 (es)
JP (1) JPH08208484A (es)
KR (1) KR100350565B1 (es)
CN (1) CN1136852C (es)
AT (1) ATE201984T1 (es)
AU (1) AU702585B2 (es)
BR (1) BR9504573A (es)
CA (1) CA2158511A1 (es)
CO (1) CO4410176A1 (es)
CZ (1) CZ287248B6 (es)
DE (2) DE69521275T2 (es)
DK (1) DK0716852T3 (es)
ES (2) ES2079327B1 (es)
FI (1) FI953887A7 (es)
GR (2) GR960300062T1 (es)
HU (1) HUT73792A (es)
IL (1) IL114642A (es)
MY (1) MY114687A (es)
NO (1) NO309925B1 (es)
NZ (1) NZ272611A (es)
PE (1) PE5196A1 (es)
PL (1) PL181437B1 (es)
PT (1) PT716852E (es)
RU (1) RU2150276C1 (es)
SI (1) SI0716852T1 (es)
TR (1) TR199501165A1 (es)
TW (1) TW492875B (es)
UA (1) UA34479C2 (es)
YU (1) YU60795A (es)
ZA (1) ZA956411B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE216887T1 (de) * 1996-02-29 2002-05-15 Fujisawa Pharmaceutical Co Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung
WO1999018965A1 (en) * 1997-10-10 1999-04-22 Yamanouchi Europe B.V. Oral compositions containing a cephalosporin antibiotic
CA2352430C (en) * 1998-12-01 2008-11-18 Novo Nordisk A/S New pharmaceutical composition and the process for its preparation
DE10005017A1 (de) * 2000-02-04 2001-08-09 Cognis Deutschland Gmbh Duftstofftabletten
JP2004531537A (ja) * 2001-05-01 2004-10-14 ファイザー・プロダクツ・インク 一様な薬剤分布と効力を有する低用量製薬組成物の製造方法
US7151432B2 (en) 2001-09-19 2006-12-19 Immersion Corporation Circuit and method for a switch matrix and switch sensing
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
JP4526247B2 (ja) * 2002-07-08 2010-08-18 第一三共株式会社 経口用セファロスポリン製剤
TW200404550A (en) * 2002-07-08 2004-04-01 Sankyo Co Cepharospolin formulation for oral use
EP1732605B1 (en) * 2004-03-29 2019-05-08 Wyeth LLC Multi-vitamin and mineral nutritional supplements
US8968768B2 (en) * 2004-03-29 2015-03-03 Wyeth Llc Phytosterol nutritional supplements
US9198862B2 (en) 2005-07-22 2015-12-01 Rubicon Research Private Limited Dispersible tablet composition
EP1923074A4 (en) 2005-08-10 2011-09-14 Shionogi & Co TABLET WHICH CAN BE ORALLY DISINTEGRATED
CN102579455B (zh) * 2012-03-19 2014-02-19 迪沙药业集团有限公司 一种稳定的头孢克洛咀嚼组合物
WO2017045742A1 (de) * 2015-09-14 2017-03-23 Merck Patent Gmbh Formulierung mit kontrollierter, verzögerter wirkstoffreisetzung
CN113750066B (zh) * 2021-10-12 2022-12-02 上海金城素智药业有限公司 一种具有临床优势的头孢克洛制剂及其制备方法和应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2259646C2 (de) * 1972-12-06 1984-11-22 Hoechst Ag, 6230 Frankfurt Hochdosierte Tabletten von Cephalosporin-Derivaten sowie Verfahren zu ihrer Herstellung
YU36970B (en) 1973-02-23 1984-08-31 Lilly Co Eli Process for obtaining 7-(amino)-acylamido-3-halocephalosporins
US3925372A (en) 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
US4143129A (en) * 1975-10-11 1979-03-06 Lilly Industries Limited Cephalexin tablets
GB2066662B (en) * 1979-12-21 1984-02-15 Glaxo Group Ltd Cephalexin powder compositions containing silicon dioxide
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
JPS601128A (ja) * 1983-06-15 1985-01-07 Shionogi & Co Ltd 作用持続型セフアクロル製剤
EP0181966A1 (en) * 1984-11-13 1986-05-28 Gist-Brocades N.V. Compression-coated dispersible tablets
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
EP0319074B1 (en) * 1987-11-30 1992-01-29 Brocades Pharma B.V. Pharmaceutical composition and process for its preparation
DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
GB9009473D0 (en) * 1990-04-27 1990-06-20 Beecham Group Plc Pharmaceutical formulation
FR2669221B1 (fr) * 1990-11-15 1993-01-15 Rhone Poulenc Sante Procede de preparation par compression directe de comprimes de derives de l'acide cephalosporanique.
ES2066092T3 (es) * 1990-11-29 1995-03-01 Wei Ming Pharmaceutical Mfg Co Coadyuvante para la formacion directa de comprimidos.
MY110880A (en) * 1991-01-30 1999-06-30 The Wellcome Foundation Ltd Water-dispersible tablets
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
IT1251999B (it) * 1991-11-11 1995-05-27 Opos Biochimica Srl Forma cristallina di un antibiotico cefalosporinico
CZ283428B6 (cs) * 1992-04-30 1998-04-15 Schering Corporation Stabilní hydratovaný suchý práškový cefalosporin vhodný pro orální aplikaci ve formě suspenze
US5503846A (en) * 1993-03-17 1996-04-02 Cima Labs, Inc. Base coated acid particles and effervescent formulation incorporating same
US5506248A (en) * 1993-08-02 1996-04-09 Bristol-Myers Squibb Company Pharmaceutical compositions having good dissolution properties
US5895664A (en) * 1993-09-10 1999-04-20 Fuisz Technologies Ltd. Process for forming quickly dispersing comestible unit and product therefrom
US5622719A (en) * 1993-09-10 1997-04-22 Fuisz Technologies Ltd. Process and apparatus for making rapidly dissolving dosage units and product therefrom
US5616344A (en) * 1994-06-14 1997-04-01 Fuisz Technologies Ltd. Apparatus and process for strengthening low density compression dosage units and product therefrom
US5595761A (en) * 1994-01-27 1997-01-21 The Board Of Regents Of The University Of Oklahoma Particulate support matrix for making a rapidly dissolving tablet
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin

Also Published As

Publication number Publication date
AU2509495A (en) 1996-06-20
HU9502160D0 (en) 1995-09-28
US5861141A (en) 1999-01-19
NZ272611A (en) 1997-08-22
JPH08208484A (ja) 1996-08-13
PL181437B1 (pl) 2001-07-31
NO953192L (no) 1996-06-14
TW492875B (en) 2002-07-01
IL114642A0 (en) 1995-11-27
CN1136852C (zh) 2004-02-04
PL309863A1 (en) 1996-06-24
AU702585B2 (en) 1999-02-25
EP1086689A2 (en) 2001-03-28
FI953887A0 (fi) 1995-08-17
EP0716852B1 (en) 2001-06-13
CO4410176A1 (es) 1997-01-09
EP1086689A3 (en) 2001-07-11
TR199501165A1 (tr) 1996-10-21
EP1086690A3 (en) 2001-07-11
ZA956411B (en) 1996-03-11
CZ199895A3 (en) 1996-07-17
BR9504573A (pt) 1997-02-25
YU60795A (sh) 1998-07-10
UA34479C2 (uk) 2001-03-15
DE69521275T2 (de) 2001-10-31
DK0716852T3 (da) 2001-09-03
CA2158511A1 (en) 1996-06-14
HUT73792A (en) 1996-09-30
DE716852T1 (de) 1997-04-03
ES2079327B1 (es) 1996-08-01
NO953192D0 (no) 1995-08-14
CZ287248B6 (en) 2000-10-11
EP1086690A2 (en) 2001-03-28
SI0716852T1 (en) 2001-12-31
FI953887L (fi) 1996-06-14
RU2150276C1 (ru) 2000-06-10
MY114687A (en) 2002-12-31
ES2079327A1 (es) 1996-01-01
ES2091738T1 (es) 1996-11-16
GR960300062T1 (en) 1996-11-30
KR100350565B1 (ko) 2003-02-05
FI953887A7 (fi) 1996-06-14
GR3036503T3 (en) 2001-11-30
ATE201984T1 (de) 2001-06-15
IL114642A (en) 1999-07-14
HK1012574A1 (en) 1999-08-06
EP0716852A1 (en) 1996-06-19
DE69521275D1 (de) 2001-07-19
PE5196A1 (es) 1996-03-26
CN1130506A (zh) 1996-09-11
KR960021026A (ko) 1996-07-18
PT716852E (pt) 2001-09-28
NO309925B1 (no) 2001-04-23

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