ES2091861T3 - Proteinas antigenicas y vacunas que las contienen para la prevencion de la coccidiosis. - Google Patents

Proteinas antigenicas y vacunas que las contienen para la prevencion de la coccidiosis.

Info

Publication number
ES2091861T3
ES2091861T3 ES91201751T ES91201751T ES2091861T3 ES 2091861 T3 ES2091861 T3 ES 2091861T3 ES 91201751 T ES91201751 T ES 91201751T ES 91201751 T ES91201751 T ES 91201751T ES 2091861 T3 ES2091861 T3 ES 2091861T3
Authority
ES
Spain
Prior art keywords
proteins
coccidiosis
antigenic proteins
hen
necatrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91201751T
Other languages
English (en)
Inventor
Karel Z Newman Jr
Thomas C Gore
John L Tedesco
Gary R Petersen
Virginia M Brothers
James G Files
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solvay SA
Original Assignee
Solvay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/805,301 external-priority patent/US5028694A/en
Priority claimed from US06/805,824 external-priority patent/US4874705A/en
Application filed by Solvay SA filed Critical Solvay SA
Application granted granted Critical
Publication of ES2091861T3 publication Critical patent/ES2091861T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE PROPORCIONAN PROTEINAS ANTIGENICAS PURIFICADAS QUE SON CAPACES DE INDUCIR EN UNA GALLINA UNA INMUNO RESPUESTA CONFIRIENDOLE PROTECCION CONTRA LA INFECCION POR EIMERIA NECATRIX Y/O EIMERIA TENELLA. UNA PROTEINA, UTIL PARA DAR PROTECCION CONTRA E. TENELLA Y E. HECATRIX HA SIDO DERIVADA DE ESPOROCITOS DE E. NECATRIX. SE HAN REVELADO TAMBIEN ANTICUERPOS MONOCLONALES DIRIGIDOS CONTRA LAS PROTEINAS ANTIGENICAS QUE PUEDEN SER USADOS PARA DAR A UNA GALLINA UNA INMUNIDAD PASIVA CONTRA LA COCCIDIOSIS. MAS ADELANTE SE PROPORCIONAN MOLECULAS ACIDO NUCLEICAS CODIFICANDO LAS PROTEINAS ANTIGENICAS TAMBIEN COMO VECTORES DE EXPRESION CONTENIENDOLOS . SE PROPORCIONAN TAMBIEN METODOS PARA PRODUCIR LAS PROTEINAS O POLIPEPTIDOS ANTIGENICOS TENIENDO SECUENCIAS AMINO ACIDAS DENTRO DE ESAS PROTEINAS.
ES91201751T 1985-12-03 1986-11-24 Proteinas antigenicas y vacunas que las contienen para la prevencion de la coccidiosis. Expired - Lifetime ES2091861T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/805,301 US5028694A (en) 1985-12-03 1985-12-03 Antigenic proteins and vaccines containing them for prevention of coccidiosis caused by eimeria Eimeria necatrix and Eimeria tenella
US06/805,824 US4874705A (en) 1985-05-16 1985-12-06 DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US80801385A 1985-12-11 1985-12-11
US80749785A 1985-12-11 1985-12-11

Publications (1)

Publication Number Publication Date
ES2091861T3 true ES2091861T3 (es) 1996-11-16

Family

ID=27505825

Family Applications (3)

Application Number Title Priority Date Filing Date
ES91201752T Expired - Lifetime ES2109254T3 (es) 1985-12-03 1986-11-24 Proteinas antigenas y vacunas que las contienen para la prevencion de cocidiosis.
ES198686202087T Expired - Lifetime ES2031819T3 (es) 1985-12-03 1986-11-24 Un metodo de preparar una proteina antigenica derivada de eimeriatenella.
ES91201751T Expired - Lifetime ES2091861T3 (es) 1985-12-03 1986-11-24 Proteinas antigenicas y vacunas que las contienen para la prevencion de la coccidiosis.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES91201752T Expired - Lifetime ES2109254T3 (es) 1985-12-03 1986-11-24 Proteinas antigenas y vacunas que las contienen para la prevencion de cocidiosis.
ES198686202087T Expired - Lifetime ES2031819T3 (es) 1985-12-03 1986-11-24 Un metodo de preparar una proteina antigenica derivada de eimeriatenella.

Country Status (9)

Country Link
EP (3) EP0453055B1 (es)
JP (3) JP2548148B2 (es)
AT (3) ATE140030T1 (es)
AU (1) AU592389B2 (es)
CA (1) CA1341166C (es)
DE (3) DE3650645T2 (es)
ES (3) ES2109254T3 (es)
GR (1) GR3025209T3 (es)
IL (3) IL97567A (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340520C (en) * 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US4874705A (en) * 1985-05-16 1989-10-17 Solvay & Cie, S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US5187080A (en) * 1984-06-05 1993-02-16 Solvay & Cie S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
US5279960A (en) * 1984-07-05 1994-01-18 Enzon Corp. 25 KD coccidial antigen of eimeria tenella
DE3855665D1 (de) * 1987-03-06 1996-12-19 Amgen Boulder Inc Polypeptide zur verwendung bei der diagnose von kokkidien-infektion und rekombinant-dns, verfahren zur herstellung derselben
NZ227595A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Recombinant production of eimeria tenella antigens and their use
NZ227597A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Eimeria tenella group b immunogens and their production
US5824656A (en) * 1988-01-15 1998-10-20 Merck & Co., Inc. Recombinant and native group B eimeria tenella immunogens useful as coccidiosis vaccines
ZA889230B (en) * 1988-02-12 1989-08-30 Us Agriculture Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated immune response and method of producing the same
AU620366B2 (en) * 1988-02-12 1992-02-20 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated response and method of producing the same
ZA893740B (en) * 1988-06-03 1990-02-28 Hoffmann La Roche Recombinant coccidiosis vaccines
ZA894726B (en) * 1988-06-27 1990-03-28 Akzo Nv Coccidiosis vaccine
DE68927350T2 (de) * 1988-07-05 1997-04-24 British Tech Group Usa Gentechnologisch hergestellter coccidiose-impfstoff
AU4647089A (en) * 1988-11-17 1990-06-12 Omar Fakhri Electro-therapy apparatus and method
NZ232372A (en) * 1989-02-10 1993-04-28 Merck & Co Inc Glycolipid-linked membrane-associated immunogens of eimeria useful in immunising poultry against coccidiosis
EP0548252A4 (en) * 1990-09-12 1995-02-15 Genex Corp Genetically engineered coccidiosis vaccine
AU654481B2 (en) * 1991-03-14 1994-11-10 British Technology Group Usa, Inc. Recombinant anticoccidial vaccine
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
DE69230037T2 (de) * 1991-07-12 2000-01-05 Pfizer Inc., New York Kontinuierliche zellinie sowie impfstoff gegen geflügelinfektion mit kokkidien
US5861160A (en) * 1995-06-07 1999-01-19 Ambico, Inc. Isospora suis sporozoite antigen
NZ500033A (en) * 1998-10-07 2001-06-29 Akzo Nobel Nv Hydrophilic eimeria polypeptides for use as coccidiosis vaccines
US6680061B1 (en) 1998-10-07 2004-01-20 Theodorus Cornelis Schaap Coccidiosis vaccines
CA2486618C (en) 2002-05-21 2013-04-09 Schering-Plough Ltd. Methods for the in vitro culture of sporozoea sp. and uses thereof
DE10330235A1 (de) * 2003-07-04 2005-01-20 Bayer Healthcare Ag Neues Eimeria Gen und Protein sowie deren Verwendung
US20220053799A1 (en) * 2020-06-26 2022-02-24 Zivo Bioscience, Inc. Positive latency effects on coccidiosis prevention and treatment via animal feed
AU2021296916A1 (en) * 2020-06-26 2023-01-19 Zivo Bioscience, Inc. Immune priming to accelerate/enhance immune response through administration of natural immune modulator
EP4152948A4 (en) * 2020-06-26 2024-08-07 Zivo Bioscience, Inc. IMMUNE PRIMING TO ACCELERATE/ENHANCE THE IMMUNE RESPONSE BY ADMINISTRATION OF A NATURAL IMMUNE MODULATOR
CN113185594B (zh) * 2021-04-26 2022-12-20 中国农业科学院兰州兽医研究所 一种柔嫩艾美耳球虫的免疫抗原、抗体及其制备方法和应用
CN120118203B (zh) * 2025-03-10 2025-08-19 安徽中起生物科技有限公司 一种抗球虫融合蛋白及其制备方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147186A (en) * 1961-04-03 1964-09-01 Auburn Res Foundation Stable coccidiosis immunization
DE2849226A1 (de) 1977-11-14 1979-05-17 Unilever Nv Verfahren zur wachstumsfoerderung von gefluegel, mittel zu seiner durchfuehrung und deren herstellung
JPS5649323A (en) 1979-09-29 1981-05-02 Nisshin Flour Milling Co Ltd Coccidiostat
JPS5780325A (en) * 1980-09-05 1982-05-19 Nat Res Dev Coccidial disease vaccine
EP0135712A3 (en) * 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against sporozoites of eimeria spp.
EP0135073A3 (en) * 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against merozites of eimeria spp.
CA1340520C (en) * 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US4639372A (en) * 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine
WO1986000528A1 (en) * 1984-07-05 1986-01-30 Genex Corporation Cloned gene and method for making and using the same
FR2780422B1 (fr) 1998-06-26 2000-09-08 Rhodia Chimie Sa Composition thermoepaississante pour bains de couchage a base d'un copolymere possedant une temperature critique inferieure de solubilite

Also Published As

Publication number Publication date
DE3650540D1 (de) 1996-08-08
ES2031819T3 (es) 1993-01-01
JP2907813B2 (ja) 1999-06-21
ATE140030T1 (de) 1996-07-15
DE3650645D1 (de) 1997-10-09
EP0453055B1 (en) 1997-09-03
JPS62224293A (ja) 1987-10-02
IL97566A0 (en) 1992-06-21
EP0453054B1 (en) 1996-07-03
IL80826A (en) 1992-06-21
ES2109254T3 (es) 1998-01-16
JP2837119B2 (ja) 1998-12-14
CA1341166C (en) 2001-01-16
DE3650540T2 (de) 1997-02-27
DE3650645T2 (de) 1998-02-19
JP2548148B2 (ja) 1996-10-30
EP0453054A3 (en) 1991-12-04
EP0453055A2 (en) 1991-10-23
EP0231537B1 (en) 1992-03-11
IL97566A (en) 1992-08-18
JPH10323195A (ja) 1998-12-08
IL97567A0 (en) 1992-06-21
AU6586986A (en) 1987-06-04
JPH08242864A (ja) 1996-09-24
EP0453054A2 (en) 1991-10-23
IL80826A0 (en) 1987-03-31
ATE73494T1 (de) 1992-03-15
AU592389B2 (en) 1990-01-11
GR3025209T3 (en) 1998-02-27
IL97567A (en) 1992-08-18
EP0453055A3 (en) 1991-11-06
EP0231537A3 (en) 1988-02-10
DE3684295D1 (de) 1992-04-16
ATE157545T1 (de) 1997-09-15
EP0231537A2 (en) 1987-08-12

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