ES2091928T3 - Metodos de prevencion de la replicacion virica. - Google Patents

Metodos de prevencion de la replicacion virica.

Info

Publication number
ES2091928T3
ES2091928T3 ES91909315T ES91909315T ES2091928T3 ES 2091928 T3 ES2091928 T3 ES 2091928T3 ES 91909315 T ES91909315 T ES 91909315T ES 91909315 T ES91909315 T ES 91909315T ES 2091928 T3 ES2091928 T3 ES 2091928T3
Authority
ES
Spain
Prior art keywords
viral replication
prevention methods
replication
viral
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91909315T
Other languages
English (en)
Inventor
Hubert E Blum
Tsanyang Liang
Eithan Galun
Jack R Wands
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24034871&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2091928(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of ES2091928T3 publication Critical patent/ES2091928T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10161—Methods of inactivation or attenuation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cookers (AREA)
  • Cold Cathode And The Manufacture (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

LA INVENCION SE REFIERE A METODOS Y COMPUESTOS PARA INHIBIR LA REPRODUCCION VIRAL. EN PARTICULAR, SE CONSIGUE LA FINALIZACION COMPLETA E IRREVERSIBLE DE LA REPRODUCCION DE UN VIRUS MEDIANTE LA INTRODUCCION DE AL MENOS UNA MUTACION EN ZONAS ESPECIFICAS EN EL GEN DE LA POLIMERASA VIRAL. EL METODO PUEDE UTILIZARSE PARA EVITAR O TRATAR INFECCIONES VIRICAS.
ES91909315T 1990-04-20 1991-04-22 Metodos de prevencion de la replicacion virica. Expired - Lifetime ES2091928T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51142890A 1990-04-20 1990-04-20

Publications (1)

Publication Number Publication Date
ES2091928T3 true ES2091928T3 (es) 1996-11-16

Family

ID=24034871

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91909315T Expired - Lifetime ES2091928T3 (es) 1990-04-20 1991-04-22 Metodos de prevencion de la replicacion virica.

Country Status (10)

Country Link
EP (1) EP0528903B1 (es)
JP (1) JPH05506993A (es)
AT (1) ATE142690T1 (es)
AU (1) AU656136B2 (es)
CA (1) CA2081022A1 (es)
DE (1) DE69122098T2 (es)
DK (1) DK0528903T3 (es)
ES (1) ES2091928T3 (es)
GR (1) GR3021656T3 (es)
WO (1) WO1991016420A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5633449A (en) * 1990-03-12 1997-05-27 Cornell Research Foundation, Inc. Induction of resistance to viral diseases in plants
US5596132A (en) * 1990-03-12 1997-01-21 Cornell Research Foundation, Inc. Induction of resistance to virus diseases by transformation of plants with a portion of a plant virus genome involving a read-through replicase gene
US5610050A (en) * 1990-04-20 1997-03-11 The General Hospital Corporation Methods of preventing viral replication
GB9208545D0 (en) * 1992-04-21 1992-06-03 Gatsby Charitable Foundation T Virus resistant plants
WO1993025068A1 (en) * 1992-06-08 1993-12-23 Cornell Research Foundation, Inc. Viral resistance by plant transformation with a replicase portion of a plant virus genome
US5869248A (en) * 1994-03-07 1999-02-09 Yale University Targeted cleavage of RNA using ribonuclease P targeting and cleavage sequences
US5683873A (en) * 1995-01-13 1997-11-04 Innovir Laboratories, Inc. EGS-mediated inactivation of target RNA
US6057153A (en) * 1995-01-13 2000-05-02 Yale University Stabilized external guide sequences
DE19517532C2 (de) 1995-05-12 1999-10-28 Max Planck Gesellschaft HBV-Vektoren und Zellen zu ihrer Bereitstellung
CN100412190C (zh) * 2001-03-15 2008-08-20 复旦大学 乙肝病毒全基因组多聚酶嵌合体的组建方法和应用
CN102643858B (zh) * 2011-02-16 2014-04-02 复旦大学 一种高效复制的人乙型肝炎病毒重组载体及其应用
RS61447B1 (sr) 2011-04-21 2021-03-31 Glaxo Group Ltd Modulacija ekspresije virusa hepatitisa b (hbv)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE201444T1 (de) * 1985-03-21 2001-06-15 Johnston Stephen Ph D Vom parasit abgeleiteter widerstand
IE892640L (en) * 1988-08-16 1990-02-16 Tate & Lyle Plc Defective hepadnaviruses and producer cell line for vaccines¹and treatment of liver diseases and disorders
NZ244820A (en) * 1991-10-25 1994-01-26 Isis Pharmaceuticals Inc Oligonucleotide inhibitor of epstein-barr virus.

Also Published As

Publication number Publication date
EP0528903A4 (en) 1993-09-08
GR3021656T3 (en) 1997-02-28
AU7785891A (en) 1991-11-11
CA2081022A1 (en) 1991-10-21
DE69122098D1 (de) 1996-10-17
JPH05506993A (ja) 1993-10-14
DE69122098T2 (de) 1997-02-20
ATE142690T1 (de) 1996-09-15
AU656136B2 (en) 1995-01-27
EP0528903A1 (en) 1993-03-03
EP0528903B1 (en) 1996-09-11
DK0528903T3 (da) 1996-09-30
WO1991016420A1 (en) 1991-10-31

Similar Documents

Publication Publication Date Title
ES2091928T3 (es) Metodos de prevencion de la replicacion virica.
ZA964445B (en) Oligonucleotides specific for hepatitis b virus
NO963860L (no) Isoprenyl-transferase-inhibitorer
EP0630280A4 (en) METHOD AND DEVICE FOR REMOVING DNA, VIRUSES AND ENDOTOXINS.
NO954217L (no) Guanosinrike antivirus-oligonukleotider
DE69533673D1 (de) Behandlung und prävention von helicobacter-infektionen
BR9204699A (pt) Compostos contendo grupamento imidazolinona ou imidazolintiona,processos de preparacoes desses compostos,composicoes fungicidas e processo de tratamento de culturas
PT98565A (pt) Um processo de producao de uma composicao para o tratamento da infeccao por hsv
ES2123156T3 (es) Compuestos y procedimientos de inhibicion de hiv y virus semejantes.
ATE165345T1 (de) Sulfonsaeurederivate zur behandlung von viruserkrankungen
ES2125976T3 (es) Otros derivados de indol con accion antiviral.
MD960168A (ro) Metodă şi compuşi pentru tratamentul infecţiilor virale
DE69004451D1 (de) Prophylaxe und Behandlung von Herpesvirus-Infektionen.
EP0600396A3 (en) Gut protozoan vaccines.
DE69730214D1 (de) Zusammensetzung und verfahren zur behandlung von herpes simplex
PT87004A (pt) Process for the preparation of compositions for the treatment of viral infections and composites 3'-azide-2',3'-didesoxy-in osine and 3'-fluoro-2',3'-didesoxyguanosine
EP1331267A3 (en) Oligonucleotides specific for hepatitis C virus
HUT44439A (en) Process for inhibiting the reproduction of viruses and virus infections
AU2396900A (en) Treatment and prevention of hiv and other viral infections
MD950289A (en) Process for uranil ions recovery out of sewage
FR2702490B1 (fr) Procédé de lyophilisation de cultures de microorganismes, lyophilisats obtenus et leur utilisation.
AU630249B2 (en) Prevention of glycoprotein enveloped virus infectivity by quinolyloxazole-2-ones
ATE56878T1 (de) Verfahren und zusammensetzung zur vorbeugung und behandlung von virus-infektionen.
DE68925356D1 (de) Nicht-zurückmutierende RNA-Viren
MX9400210A (es) Tratamiento de infecciones virales.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 528903

Country of ref document: ES