ES2093025T3 - Produccion del factor de crecimiento de celulas endoteliales y adn de codificacion del mismo. - Google Patents

Produccion del factor de crecimiento de celulas endoteliales y adn de codificacion del mismo.

Info

Publication number
ES2093025T3
ES2093025T3 ES90907682T ES90907682T ES2093025T3 ES 2093025 T3 ES2093025 T3 ES 2093025T3 ES 90907682 T ES90907682 T ES 90907682T ES 90907682 T ES90907682 T ES 90907682T ES 2093025 T3 ES2093025 T3 ES 2093025T3
Authority
ES
Spain
Prior art keywords
growth factor
endothelial cells
production
same
coding dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90907682T
Other languages
English (en)
Inventor
Napoleone Ferrara
David Wai-Hung Leung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ES2093025T3 publication Critical patent/ES2093025T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LOS AISLADORES DE ADN QUE CODIFICAN EL FACTOR DE CRECIMIENTO CELULAR ENDOTELIAL PUEDEN SER UTILIZADOS PARA PRODUCIR LA PROTEINA MEDIANTE SISTEMAS DE EXPRESION RECOMBINANTES. DICHA PROTEINA ES TERAPEUTICAMENTE UTIL PARA TRATAR CONDICIONES EN QUE SE DESEA UNA ACCION SELECTIVA EN LAS CELULAS ENDOTELIALES VASCULARES, EN AUSENCIA DE UNA PROLIFERACION DEL TEJIDO CONECTOR EXCESIVA.
ES90907682T 1989-05-12 1990-05-09 Produccion del factor de crecimiento de celulas endoteliales y adn de codificacion del mismo. Expired - Lifetime ES2093025T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35111789A 1989-05-12 1989-05-12
US36942489A 1989-06-21 1989-06-21
US07/389,722 US5332671A (en) 1989-05-12 1989-08-04 Production of vascular endothelial cell growth factor and DNA encoding same

Publications (1)

Publication Number Publication Date
ES2093025T3 true ES2093025T3 (es) 1996-12-16

Family

ID=27407983

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90907682T Expired - Lifetime ES2093025T3 (es) 1989-05-12 1990-05-09 Produccion del factor de crecimiento de celulas endoteliales y adn de codificacion del mismo.

Country Status (14)

Country Link
US (2) US5332671A (es)
EP (1) EP0471754B1 (es)
JP (1) JP3117992B2 (es)
AT (1) ATE140968T1 (es)
AU (1) AU635935B2 (es)
CA (1) CA2054699C (es)
DE (1) DE69027990T2 (es)
DK (1) DK0471754T3 (es)
ES (1) ES2093025T3 (es)
IE (1) IE74169B1 (es)
IL (2) IL94128A (es)
NZ (1) NZ233451A (es)
PT (1) PT93996B (es)
WO (1) WO1990013649A1 (es)

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ATE140968T1 (de) 1996-08-15
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PT93996A (pt) 1991-01-08
DE69027990D1 (de) 1996-09-05
IL94128A0 (en) 1991-01-31
IL94128A (en) 2005-11-20
DE69027990T2 (de) 1997-01-30
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CA2054699A1 (en) 1990-11-13
WO1990013649A1 (en) 1990-11-15
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US5332671A (en) 1994-07-26
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