ATE142500T1 - Doppelsträngige rns zur korrektur von abnormalitäten von zirkulierenden immunkomplexen und der monozytenfunktion - Google Patents

Doppelsträngige rns zur korrektur von abnormalitäten von zirkulierenden immunkomplexen und der monozytenfunktion

Info

Publication number
ATE142500T1
ATE142500T1 AT88306418T AT88306418T ATE142500T1 AT E142500 T1 ATE142500 T1 AT E142500T1 AT 88306418 T AT88306418 T AT 88306418T AT 88306418 T AT88306418 T AT 88306418T AT E142500 T1 ATE142500 T1 AT E142500T1
Authority
AT
Austria
Prior art keywords
double
stranded rna
immune complexes
circulative
abnormalities
Prior art date
Application number
AT88306418T
Other languages
English (en)
Inventor
William A Carter
Original Assignee
Hem Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Pharma Corp filed Critical Hem Pharma Corp
Application granted granted Critical
Publication of ATE142500T1 publication Critical patent/ATE142500T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
AT88306418T 1987-07-17 1988-07-13 Doppelsträngige rns zur korrektur von abnormalitäten von zirkulierenden immunkomplexen und der monozytenfunktion ATE142500T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7461687A 1987-07-17 1987-07-17
US12457787A 1987-11-24 1987-11-24

Publications (1)

Publication Number Publication Date
ATE142500T1 true ATE142500T1 (de) 1996-09-15

Family

ID=26755855

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88306418T ATE142500T1 (de) 1987-07-17 1988-07-13 Doppelsträngige rns zur korrektur von abnormalitäten von zirkulierenden immunkomplexen und der monozytenfunktion

Country Status (18)

Country Link
EP (1) EP0300680B1 (de)
JP (1) JP2601520B2 (de)
KR (1) KR0131880B1 (de)
CN (1) CN1035050A (de)
AT (1) ATE142500T1 (de)
AU (2) AU1820588A (de)
CA (1) CA1326999C (de)
DE (1) DE3855527T2 (de)
DK (1) DK399288A (de)
ES (1) ES2093607T3 (de)
FI (1) FI883352A7 (de)
HU (1) HUT47432A (de)
IE (1) IE76914B1 (de)
IL (1) IL86862A (de)
NO (1) NO175023C (de)
NZ (1) NZ225310A (de)
OA (1) OA08890A (de)
PT (1) PT87996B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963532A (en) * 1987-11-25 1990-10-16 Hem Research, Inc. dsRNA-based prevention of viral escape
JPH04507083A (ja) * 1989-05-19 1992-12-10 ヘム・リサーチ・インコーポレーテッド 規定された構造の短い治療用ｄｓＲＮＡ
ZA908037B (en) * 1989-10-11 1991-09-25 Hem Res Inc Protection from shock subsequent to injury by double-standed rnas
ATE147630T1 (de) * 1989-10-11 1997-02-15 Hem Pharma Corp Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's
US5132292A (en) * 1990-05-25 1992-07-21 Hem Research, Inc. Treatment of viral hepatitis
GB9108085D0 (en) * 1991-04-16 1991-06-05 Scras Complexes of polyadenylic acid with polyuridylic acid
EP0596912A4 (en) * 1991-07-16 1994-07-27 Hem Pharma Corp Modulation and diagnosis of cytokine dysfunctions.
FR2766715B1 (fr) * 1997-08-04 2001-02-16 Scras Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale
FR2768344B1 (fr) * 1997-08-26 2001-02-16 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale
FR2768345B1 (fr) * 1997-09-17 2001-05-04 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale
AR013269A1 (es) * 1997-08-04 2000-12-13 Scras Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
KR20010042069A (ko) 1998-03-20 2001-05-25 베니텍 오스트레일리아 리미티드 유전자 발현 조절방법
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
EP2314700A1 (de) 1999-01-28 2011-04-27 Medical College of Georgia Research Institute, Inc Zusammensetzung und Verfahren zur in vivo und in vitro Abschwächung der Genexpression mittels dobbelsträngiger RNA
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
US20020132257A1 (en) 2001-01-31 2002-09-19 Tony Giordano Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
EP2351576A1 (de) * 2004-12-29 2011-08-03 Mannkind Corporation Verfahren zum Auslösen, Beibehalten und Manipulieren von Immunantworten durch gezielte Verabreichung von Modifikationsmitteln der biologischen Reaktion in lymphatische Organe
ES2715251B1 (es) * 2015-11-17 2020-09-07 Bioncotech Therapeutics S L Novedosa composicion farmaceutica que comprende particulas que comprenden un complejo de un polirribonucleotido de doble cadena y una polialquilenimina
CN105434341B (zh) * 2015-12-22 2018-07-10 肇庆大华农生物药品有限公司 一种兽用聚腺尿苷酸注射液及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024222A (en) * 1973-10-30 1977-05-17 The Johns Hopkins University Nucleic acid complexes
US4140761A (en) * 1977-04-11 1979-02-20 The United States Of America As Represented By The Department Of Health, Education & Welfare Modification of hepatitis B virus infection in chronic carriers of hepatitis B surface antigen
DE3380200D1 (en) * 1982-09-16 1989-08-24 William Alvin Carter Anti-proliferative action of dsnras on tumor cells
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)

Also Published As

Publication number Publication date
DE3855527D1 (de) 1996-10-17
NO882853D0 (no) 1988-06-28
DE3855527T2 (de) 1997-04-03
KR0131880B1 (ko) 1998-04-17
KR890001580A (ko) 1989-03-27
PT87996A (pt) 1989-06-30
PT87996B (pt) 1995-03-31
FI883352L (fi) 1989-01-18
IE881894L (en) 1989-01-17
NO175023B (no) 1994-05-09
AU1820588A (en) 1989-01-19
EP0300680A2 (de) 1989-01-25
ES2093607T3 (es) 1997-01-01
FI883352A0 (fi) 1988-07-14
NZ225310A (en) 1991-05-28
EP0300680A3 (de) 1991-06-19
CN1035050A (zh) 1989-08-30
NO882853L (no) 1989-01-18
EP0300680B1 (de) 1996-09-11
DK399288A (da) 1989-01-18
JPS6490126A (en) 1989-04-06
OA08890A (en) 1989-10-31
NO175023C (no) 1994-08-17
IL86862A0 (en) 1988-11-30
FI883352A7 (fi) 1989-01-18
CA1326999C (en) 1994-02-15
IL86862A (en) 1993-05-13
JP2601520B2 (ja) 1997-04-16
IE76914B1 (en) 1997-11-05
DK399288D0 (da) 1988-07-15
HUT47432A (en) 1989-03-28
AU1761195A (en) 1995-06-29

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee