ES2095224T3 - Sales de litio como reactivos para la lisis eritrocitaria y para la desnaturalizacion de la hemoglobina. - Google Patents

Sales de litio como reactivos para la lisis eritrocitaria y para la desnaturalizacion de la hemoglobina.

Info

Publication number
ES2095224T3
ES2095224T3 ES90112657T ES90112657T ES2095224T3 ES 2095224 T3 ES2095224 T3 ES 2095224T3 ES 90112657 T ES90112657 T ES 90112657T ES 90112657 T ES90112657 T ES 90112657T ES 2095224 T3 ES2095224 T3 ES 2095224T3
Authority
ES
Spain
Prior art keywords
hemoglobin
lysis
erythrocital
denaturalization
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90112657T
Other languages
English (en)
Inventor
Lynette Lewis
Teresa M Yip
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of ES2095224T3 publication Critical patent/ES2095224T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

USO DE UNA SAL DE LITIO, EN PARTICULAR DIOCIANATO DE LITIO, COMO REACTIVO PARA LISINAR GLOBULOS ROJOS Y DESNATURALIZAR HEMOGLOBINA EN LA REALIZACION DE UN INMUNOENSAYO PARA DETECTAR LA CANTIDAD RELATIVA DE UN DERIVADO DE HEMOGLOBINA EN UNA MUESTRA DE SANGRE. EL METODO ES PARTICULARMENTE UTIL PARA DETERMINAR LA HEMOGLOBINA A1C. EL METODO PROPORCIONA UN MEDIO RAPIDO PARA LIBERAR HEMOGLOBINA DE LOS GLOBULOS ROJOS POR LISINA Y PARA EXPONER EL EPITOPE CARACTERISTICO DE LA FORMA A1C. LAS CONCENTRACIONES BAJAS DE LA SAL DE LITIO PROPORCIONAN UNA RAPIDA LIBERACION Y DESNATURALIZACION DE LA HEMOGLOBINA SIN NECESIDAD DE REALIZAR UNA DILUCION ANTES DEL INMUNOENSAYO.
ES90112657T 1989-07-13 1990-07-03 Sales de litio como reactivos para la lisis eritrocitaria y para la desnaturalizacion de la hemoglobina. Expired - Lifetime ES2095224T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37958289A 1989-07-13 1989-07-13

Publications (1)

Publication Number Publication Date
ES2095224T3 true ES2095224T3 (es) 1997-02-16

Family

ID=23497825

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90112657T Expired - Lifetime ES2095224T3 (es) 1989-07-13 1990-07-03 Sales de litio como reactivos para la lisis eritrocitaria y para la desnaturalizacion de la hemoglobina.

Country Status (12)

Country Link
EP (1) EP0407860B1 (es)
JP (1) JP2843919B2 (es)
AT (1) ATE145991T1 (es)
AU (1) AU625137B2 (es)
DE (1) DE69029291T2 (es)
DK (1) DK0407860T3 (es)
ES (1) ES2095224T3 (es)
FI (1) FI102698B1 (es)
GR (1) GR3022522T3 (es)
HU (1) HU206157B (es)
IE (1) IE902549A1 (es)
IL (1) IL94724A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151369A (en) * 1989-07-13 1992-09-29 Miles Inc. Lithium salts as red blood cell lysing and hemoglobin denaturing reagents
US5236664A (en) * 1991-04-08 1993-08-17 University Of South Alabama Apparatus for monitoring blood loss
DE4206932A1 (de) * 1992-03-05 1993-09-09 Boehringer Mannheim Gmbh Immunologische methode zur bestimmung eines haemoglobinderivates
US5610076A (en) * 1994-04-29 1997-03-11 Alteon Inc. Method for detecting hemoglobin advanced glycosylation endproducts
US6174734B1 (en) 1997-10-24 2001-01-16 Abbott Laboratories Measurement of glycated hemoglobin
US20050014275A1 (en) * 2002-03-29 2005-01-20 Fumihisa Kitawaki Blood processing method, blood processing device, method of measuring hemoglobins and device for measuring hemoglobins
JP4957547B2 (ja) 2005-04-14 2012-06-20 パナソニック株式会社 ヘモグロビン誘導体の測定方法、それに用いる試薬組成物、測定キット、分析デバイス、及び分析システム
CN102879558B (zh) 2007-10-04 2015-09-16 松下健康医疗器械株式会社 分析用仪器和使用该分析用仪器的分析装置及分析方法
WO2009057293A1 (ja) 2007-10-30 2009-05-07 Panasonic Corporation ヘモグロビン及びヘモグロビン誘導体の測定方法、測定キット
CN102246036B (zh) 2008-12-11 2016-01-20 积水医疗株式会社 含有糖化血红蛋白的试样的前处理方法
EP3920779A4 (en) * 2019-02-06 2022-03-09 Siemens Healthcare Diagnostics, Inc. PROCEDURE FOR BLOOD SAMPLE SUSPENSION

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339952C (en) * 1984-10-29 1998-07-14 William J. Knowles Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto
US4970171A (en) * 1987-11-09 1990-11-13 Miles Inc. Denaturant reagents for convenient determination of hemoglobin derivatives in blood

Also Published As

Publication number Publication date
IL94724A0 (en) 1991-04-15
JP2843919B2 (ja) 1999-01-06
DE69029291T2 (de) 1997-04-03
EP0407860A2 (en) 1991-01-16
EP0407860B1 (en) 1996-12-04
HU904183D0 (en) 1990-12-28
AU625137B2 (en) 1992-07-02
IE902549A1 (en) 1991-02-27
GR3022522T3 (en) 1997-05-31
HU206157B (en) 1992-08-28
JPH0351759A (ja) 1991-03-06
FI102698B (fi) 1999-01-29
DK0407860T3 (da) 1997-05-12
DE69029291D1 (de) 1997-01-16
EP0407860A3 (en) 1992-03-04
IL94724A (en) 1994-02-27
HUT57902A (en) 1991-12-30
FI903510A0 (fi) 1990-07-11
ATE145991T1 (de) 1996-12-15
AU5890990A (en) 1991-01-17
FI102698B1 (fi) 1999-01-29

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