ES2096486T3 - Procedimiento y dispositivo para la determinacion de un analito en una muestra. - Google Patents

Procedimiento y dispositivo para la determinacion de un analito en una muestra.

Info

Publication number
ES2096486T3
ES2096486T3 ES94927705T ES94927705T ES2096486T3 ES 2096486 T3 ES2096486 T3 ES 2096486T3 ES 94927705 T ES94927705 T ES 94927705T ES 94927705 T ES94927705 T ES 94927705T ES 2096486 T3 ES2096486 T3 ES 2096486T3
Authority
ES
Spain
Prior art keywords
sample
liquid phase
analyte
reagent
aggregates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94927705T
Other languages
English (en)
Inventor
Bruno Colin
Michel Goudard
Alain Theretz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA filed Critical Biomerieux SA
Application granted granted Critical
Publication of ES2096486T3 publication Critical patent/ES2096486T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO PARA LA DETERMINACION DE UN ANALITO EN UNA MUESTRA, SEGUN EL CUAL: (I) SE DISPONE DICHA MUESTRA EN FASE LIQUIDA, CUYO ANALITO COMPRENDE UN LIGANDO QUE TIENE AL MENOS UN LUGAR DE RECONOCIMIENTO ESPECIFICO DE UN ANTILIGANDO, (II) SE DISPONE DE AL MENOS UN REACTIVO QUE COMPRENDE PARTICULAS METALICAS EN SUSPENSION EN FASE LIQUIDA, NO SEPARABLES DE DICHA FASE LIQUIDA POR VIA MAGNETICA O ELECTROMAGNETICA, COMPRENDIENDO CADA PARTICULA UN NUCLEO METALICO SOBRE EL CUAL ESTA FIJADO DIRECTA O INDIRECTAMENTE AL MENOS UN ANTILIGANDO; (III) SE PONE EN CONTACTO, LA MUESTRA Y EL REACTIVO, EVENTUALMENTE CON OTRO REACTIVO; (IV) SE COLOCAN LOS AGREGADOS METALICOS BAJO UN CAMPO MAGNETICO; V) SE DETECTAN LOS AGREGADOS METALICOS, PARA OBTENER UNA SEÑAL REPRESENTATIVA DE LA MASA METALICA DE DICHOS AGREGADOS, CORRELACIONADOS CON LA CANTIDAD DE ANALITO PRESENTE EN ORIGEN EN LA MUESTRA, SIENDO DETECTADA LA MASA METALICA MEDIANTE UN DETECTOR MAGNETICO O MAGNETIZABLE, GENERANDO ELCAMPO SEGUN (IV), COLOCADO CERCA DE LA MUESTRA, Y SOMETIDA A UN DESPLAZAMIENTO O A UNA FUERZA BAJO EL EFECTO DE LOS AGREGADOS METALICOS UNIDOS, PARA OBTENER UNA SEÑAL DE DESPLAZAMIENTO O DE FUERZA, REPRESENTATIVO DE LA MASA METALICA DE LOS AGREGADOS. LA INVENCION SE REFIERE TAMBIEN A UN DISPOSITIVO PARA APLICAR ESTE PROCESO.
ES94927705T 1993-09-20 1994-09-20 Procedimiento y dispositivo para la determinacion de un analito en una muestra. Expired - Lifetime ES2096486T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9311363A FR2710410B1 (fr) 1993-09-20 1993-09-20 Procédé et dispositif pour la détermination d'un analyte dans un échantillon .

Publications (1)

Publication Number Publication Date
ES2096486T3 true ES2096486T3 (es) 1997-03-01

Family

ID=9451184

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94927705T Expired - Lifetime ES2096486T3 (es) 1993-09-20 1994-09-20 Procedimiento y dispositivo para la determinacion de un analito en una muestra.

Country Status (8)

Country Link
US (1) US5773307A (es)
EP (1) EP0720743B1 (es)
AT (1) ATE147166T1 (es)
CA (1) CA2172041C (es)
DE (1) DE69401359T2 (es)
ES (1) ES2096486T3 (es)
FR (1) FR2710410B1 (es)
WO (1) WO1995008769A1 (es)

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FR2758884B1 (fr) * 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
US6908770B1 (en) 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
US6592820B1 (en) * 1998-11-05 2003-07-15 Bio-Spectrum Technologies, Inc. System and method for biochemical assay
US7022517B1 (en) 1999-07-16 2006-04-04 Board Of Regents, The University Of Texas System Method and apparatus for the delivery of samples to a chemical sensor array
AU1325201A (en) 1999-07-16 2001-02-05 Board Of Regents, The University Of Texas System Detection system based on an analyte reactive particle
ATE403145T1 (de) * 2000-01-31 2008-08-15 Univ Texas Tragbare vorrichtung mit einer sensor-array- anordnung
US20020160363A1 (en) * 2001-01-31 2002-10-31 Mcdevitt John T. Magnetic-based placement and retention of sensor elements in a sensor array
US20020197622A1 (en) * 2001-01-31 2002-12-26 Mcdevitt John T. Method and apparatus for the confinement of materials in a micromachined chemical sensor array
WO2002063270A2 (en) * 2001-02-05 2002-08-15 Board Of Regents, The University Of Texas System The use of mesoscale self-assembly and recognition to effect delivery of sensing reagent for arrayed sensors
US8257967B2 (en) 2002-04-26 2012-09-04 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
EP1546367A4 (en) * 2002-07-24 2006-08-16 Univ Texas INFLUENCE AND DETECTION OF MICROBES WITH MEMBRANE PROCESSES
JP2004157072A (ja) * 2002-11-08 2004-06-03 Japan Science & Technology Agency 免疫反応測定に用いられる高感度磁性マーカー
US7601491B2 (en) * 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
US20040157219A1 (en) * 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
WO2004097371A2 (en) * 2003-04-25 2004-11-11 Board Of Regents, The University Of Texas System System and method for the detection of analytes
US9317922B2 (en) 2003-05-16 2016-04-19 Board Of Regents The University Of Texas System Image and part recognition technology
WO2004104922A2 (en) * 2003-05-16 2004-12-02 Board Of Regents, The University Of Texas System Image and part recognition technology
EP1695082A2 (en) * 2003-12-11 2006-08-30 Board of Regents, The University of Texas System Method and system for the analysis of saliva using a sensor array
US20060257854A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Membrane assay system including preloaded particles
US20060257941A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle and membrane sensor elements
US8105849B2 (en) 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US20060257991A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
US7781226B2 (en) * 2004-02-27 2010-08-24 The Board Of Regents Of The University Of Texas System Particle on membrane assay system
US20050239091A1 (en) * 2004-04-23 2005-10-27 Collis Matthew P Extraction of nucleic acids using small diameter magnetically-responsive particles
US20060024776A1 (en) * 2004-08-02 2006-02-02 Mcmillian Ray Magnetic particle capture of whole intact organisms from clinical samples
JP2008511816A (ja) * 2004-08-03 2008-04-17 ベクトン・ディキンソン・アンド・カンパニー サンプルを分別するための磁性材料の使用
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EP1899450A4 (en) * 2005-06-24 2010-03-24 Univ Texas SYSTEMS AND METHODS INCLUDING INCLUDED CASSETTES WITH DEFINITION SYSTEMS AND LIQUIDITY SUPPLY SYSTEMS
AU2006284832B2 (en) * 2005-08-31 2011-06-02 T2 Biosystems Inc. NMR device for detection of analytes involving magnetic particles
US20070166730A1 (en) 2006-01-19 2007-07-19 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
US8339135B2 (en) 2006-08-21 2012-12-25 Stc.Unm Biological detector and method
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US9476812B2 (en) 2010-04-21 2016-10-25 Dna Electronics, Inc. Methods for isolating a target analyte from a heterogeneous sample
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Also Published As

Publication number Publication date
FR2710410B1 (fr) 1995-10-20
CA2172041C (fr) 1999-08-10
US5773307A (en) 1998-06-30
CA2172041A1 (fr) 1995-03-30
WO1995008769A1 (fr) 1995-03-30
FR2710410A1 (fr) 1995-03-31
ATE147166T1 (de) 1997-01-15
DE69401359D1 (de) 1997-02-13
EP0720743B1 (fr) 1997-01-02
DE69401359T2 (de) 1997-04-30
EP0720743A1 (fr) 1996-07-10

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