ES2096596T3 - Procedimiento para la determinacion inmunologica de ligandos. - Google Patents

Procedimiento para la determinacion inmunologica de ligandos.

Info

Publication number
ES2096596T3
ES2096596T3 ES91102712T ES91102712T ES2096596T3 ES 2096596 T3 ES2096596 T3 ES 2096596T3 ES 91102712 T ES91102712 T ES 91102712T ES 91102712 T ES91102712 T ES 91102712T ES 2096596 T3 ES2096596 T3 ES 2096596T3
Authority
ES
Spain
Prior art keywords
binding
ligand
immunological determination
determined
leagues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91102712T
Other languages
English (en)
Inventor
Arno Dr Deger
Roland Dr Schenk
Gerhard Dr Bienhaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2096596T3 publication Critical patent/ES2096596T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE PRESENTA UN PROCESO PARA LA DETERMINACION INMUNOLOGICA DE UNA LIGADURA, DONDE SE DETERMINA ESTA LIGADURA CON: A) AL MENOS DOS MOLECULAS DE UNA SUSTANCIA P2 DE CAPACIDAD DE LIGADURA ESPECIFICA, DE LAS QUE AL MENOS UNA DE ESTAS MOLECULAS PORTA UNA MARCA Y B) UN RECEPTOR R QUE SE COMPONE DE UN COMPONENTE DE LIGADURA P1 CON CAPACIDAD DE LIGADO PARA EL MONOVALENTE P2 Y UN ENLACE EN UN LUGAR DE R1 PARA LA DETERMINACION DE LA LIGADURA Y DE ESTA FORMA DETERMINAR LA MARCA. ASI COMO UN REACTIVO PARA LA DETERMINACION INMUNOLOGICA DE UNA LIGADURA QUE CONTIENE UNA SUSTANCIA P2 CON ESPECIFICA CAPACIDAD DE ENLACE, DONDE EXISTE AL MENOS PARCIALMENTE LA FORMA MARCADA Y UN RECEPTOR R, QUE SE COMPONE DE UN COMPONENTE DE ENLACE P1 CON CAPACIDAD DE ENLACE MONOVALENTE PARA P2 Y UNA POSICION DE ENLACE R1 PARA LA LIGADURA DETERMINADA.
ES91102712T 1990-02-26 1991-02-25 Procedimiento para la determinacion inmunologica de ligandos. Expired - Lifetime ES2096596T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4006054A DE4006054A1 (de) 1990-02-26 1990-02-26 Verfahren zur immunologischen bestimmung von liganden

Publications (1)

Publication Number Publication Date
ES2096596T3 true ES2096596T3 (es) 1997-03-16

Family

ID=6401009

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91102712T Expired - Lifetime ES2096596T3 (es) 1990-02-26 1991-02-25 Procedimiento para la determinacion inmunologica de ligandos.

Country Status (9)

Country Link
EP (1) EP0444561B1 (es)
JP (1) JP2501960B2 (es)
KR (1) KR940008091B1 (es)
AT (1) ATE145479T1 (es)
AU (1) AU647449B2 (es)
CA (1) CA2034922A1 (es)
DE (2) DE4006054A1 (es)
ES (1) ES2096596T3 (es)
ZA (1) ZA911343B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7138251B1 (en) 1996-04-22 2006-11-21 Amgen Inc. Polynucleotides encoding a neurotrophic factor receptor
WO1998054213A2 (en) * 1997-05-30 1998-12-03 Amgen Inc. Neurotrophic factor receptors
WO2005062048A1 (de) 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Homogenes nachweisverfahren

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5510590A (en) * 1978-05-04 1980-01-25 Wellcome Found Enzyme immunity quantity analysis
US4228237A (en) * 1978-09-21 1980-10-14 Calbiochem-Behring Corp. Methods for the detection and determination of ligands
US4495296A (en) * 1979-05-21 1985-01-22 New York Blood Center, Inc. Labeled anti-hapten antibodies and their use as a universal reagent for solid phase radio- and/or enzyme-immunoassays
IL75020A (en) * 1984-05-10 1988-10-31 Abbott Lab Biotin-antibiotin immunoassay for the detection of ligands
JPS60252265A (ja) * 1984-05-29 1985-12-12 Toray Ind Inc 発光試薬およびそれを用いる生物学的に活性な物質の測定法
IE64286B1 (en) * 1988-05-25 1995-07-26 Boehringer Mannheim Gmbh Process for the determination of an immunologically detectable substance and a suitable vessel therefor
DE3834766A1 (de) * 1988-10-12 1990-04-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz

Also Published As

Publication number Publication date
KR940008091B1 (ko) 1994-09-02
DE59108355D1 (de) 1997-01-02
KR910021586A (ko) 1991-12-20
AU647449B2 (en) 1994-03-24
ATE145479T1 (de) 1996-12-15
EP0444561B1 (de) 1996-11-20
EP0444561A2 (de) 1991-09-04
JPH04216465A (ja) 1992-08-06
AU7101391A (en) 1991-08-29
EP0444561A3 (en) 1992-10-14
ZA911343B (en) 1991-11-27
JP2501960B2 (ja) 1996-05-29
CA2034922A1 (en) 1991-08-27
DE4006054A1 (de) 1991-08-29

Similar Documents

Publication Publication Date Title
PT89889A (pt) Processo para a preparacao de testes imunologicos contendo derivados de igg polimericos para a compensacao de factores perturbantes
ATE112059T1 (de) Verfahren zur bestimmung eines analyten.
DE3584796D1 (de) Verfahren und vorrichtung zur durchfuehrung analytischer bestimmungen.
DE59409947D1 (de) Verringerung des Hook-Effekts in Immuntests mit teilchenförmigem Trägermaterial
ES511797A0 (es) "metodo para ensayar reacciones antigeno-anticuerpo".
ATE80466T1 (de) Verfahren und reagenz zur bestimmung eines reaktionspartners einer immunologischen reaktion.
DK603087D0 (da) Immunokemisk metod tilbestemmelse af stabilt glycosyleret haemoglobin
NO874453D0 (no) Fremgangsmaate til bestemmelse av anti-hiv, middel dertil og dets anvendelse i fremgangsmaaten.
ES2096596T3 (es) Procedimiento para la determinacion inmunologica de ligandos.
ATE67599T1 (de) Heterogenes immunoassay.
ATE90790T1 (de) Verfahren zur herstellung einer festphasenmatrix.
DE3485265D1 (de) Verfahren zur bestimmung eines polyvalenten antigens und reagenz hierfuer.
ATE52251T1 (de) Histamin-derivate, immunogen-konjugate und dadurch induzierte antikoerper.
ATE77487T1 (de) Immunologisches bestimmungsverfahren zur bestimmung von hapteneigenschaften aufweisenden freien substanzen.
FI905350A7 (fi) Leimattua streptokokki-vasta-ainetta sisältävä koostumus, testipakkaus ja analyysimenetelmä, jossa sitä käytetään
FI95928C (fi) Molekyylit, joissa on vasta-ainetta liittävät kohdat ja joilla on stereospesifinen katalyysi
ATE116063T1 (de) Immunassay von elastase-1.
NO993198D0 (no) Metode for mÕling av tyroglobulin
JPS5386014A (en) Quantitative analysis of antigen and antibody
EP0650054A3 (de) Verfahren und Vorrichtung zur Gewinnung und zum Nachweis von immunologisch aktiven Substanzen aus der Gasphase.
DE3569828D1 (en) Method for immobilizing substances in synthetic solid phases, and synthetic solid phases for use in immunosorbent assays
DE3365111D1 (en) Labelled conjugates of ethosuximide, ethosuximide immunogens, antibodies thereto, immunoassay method employing the antibodies and reagent means, test kit and test device for the immunoassay method
IT7822489A0 (it) Reattivo a piu' componenti e metodo enzimatico in cinetica per la determinazione dell'ammoniaca nel sangue.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 444561

Country of ref document: ES