ES2097355T3 - Metodo para el diagnostico in vitro de alergias y otras enfermedades inflamatorias. - Google Patents

Metodo para el diagnostico in vitro de alergias y otras enfermedades inflamatorias.

Info

Publication number
ES2097355T3
ES2097355T3 ES92920592T ES92920592T ES2097355T3 ES 2097355 T3 ES2097355 T3 ES 2097355T3 ES 92920592 T ES92920592 T ES 92920592T ES 92920592 T ES92920592 T ES 92920592T ES 2097355 T3 ES2097355 T3 ES 2097355T3
Authority
ES
Spain
Prior art keywords
slt
pct
bound
carrier
allergies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92920592T
Other languages
English (en)
Inventor
Weck Alain Ladislas De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2097355T3 publication Critical patent/ES2097355T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/88—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving prostaglandins or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

EL METODO PARA LA DETECCION DE SULFIDOLEUCOTRIENOS SLT DEL GRUPO LTC4, LTD4 Y LTE4 POR MEDIO DE UN SOLO ENSAYO DE ELISA INMUNOENZIMATICO SE BASA EN LA INTERACCION ENTRE UNO O VARIOS ANTICUERPOS ANTI-SLT MONOCLONALES Y UN SLT CONJUGADO A UNA ENZIMA REVELADORA. SE PONE EN CONTACTO UNA MUESTRA BIOLOGICA, EN DONDE SE SUPONE UN CONTENIDO DE SLT, CON UN ANTICUERPO ANTI-SLT MONOCLONAL UNIDO A UN PORTADOR. DESPUES DE QUE EL SLT PRESENTE EN LA MUESTRA SE HAYA UNIDO A DICHO ANTICUERPO, SE AÑADE UN CONJUGADO DE UN SLT CON UNA ENZIMA REVELADORA AL PORTADOR CARGADO. FINALMENTE SE EVALUA LA CANTIDAD DE CONJUGADO UNIDO AL PORTADOR, CUYA CANTIDAD SE ENCUENTRA EN CORRELACION INVERSA AL SLT UNIDO AL PORTADOR. EL METODO ES UTIL PARA ENSAYOS IN VITRO PARA EL DIAGNOSTICO DE ENFERMEDADES INFLAMATORIAS, TALES COMO ENFERMEDADES REUMATICAS, INMUNODEFICIENCIAS, ALERGIAS O PSEUDOALERGIAS. LA SENSIBILIDAD DEL METODO SE PUEDE INCREMENTAR POR IMPRIMACION DE LAS MUESTRAS BIOLOGICAS CON CITOQUINAS, EJ. CON IL3, IL5 O GM-CSF COMO AGENTES DE IMPRIMACION. EL ENSAYO ES SUFICIENTEMENTE SENSIBLE COMO PARA DETECTAR EL SLT PRODUCIDO POR UNAS POCAS CELULAS REACTIVAS EN VOLUMENES POR MINUTO DE SANGRE SANA.
ES92920592T 1991-10-01 1992-09-25 Metodo para el diagnostico in vitro de alergias y otras enfermedades inflamatorias. Expired - Lifetime ES2097355T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH290491 1991-10-01

Publications (1)

Publication Number Publication Date
ES2097355T3 true ES2097355T3 (es) 1997-04-01

Family

ID=4244230

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92920592T Expired - Lifetime ES2097355T3 (es) 1991-10-01 1992-09-25 Metodo para el diagnostico in vitro de alergias y otras enfermedades inflamatorias.

Country Status (9)

Country Link
US (1) US5487977A (es)
EP (1) EP0559871B1 (es)
JP (1) JPH06503427A (es)
AT (1) ATE148234T1 (es)
AU (1) AU651249B2 (es)
CA (1) CA2097417A1 (es)
DE (1) DE69217038T2 (es)
ES (1) ES2097355T3 (es)
WO (1) WO1993007493A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI951778A7 (fi) * 1995-04-12 1996-10-13 Oy Aboatech Ab Menetelmä allergian toteamiseksi
US5739001A (en) * 1996-10-29 1998-04-14 E. I. Du Pont De Nemours And Company Solid phase cell-based assay
US6919076B1 (en) 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
US6958148B1 (en) 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
EP1265069B1 (de) * 2001-06-05 2003-09-17 Hanns-Wolf Baenkler Diagnostisches Verfahren auf der Grundlage von Lipidmessparameter-Modulations/Effektorquotientenprofilen
US8029454B2 (en) * 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
US20150152172A1 (en) * 2013-10-25 2015-06-04 Lpath, Inc. Compositions and methods for binding cysteinyl leukotrienes (cyslts) for treatment of disease
CN112415191A (zh) * 2020-11-06 2021-02-26 郑州人福博赛生物技术有限责任公司 一种白细胞三烯检测试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3218270A1 (de) * 1982-05-14 1983-11-17 Bayer Ag, 5090 Leverkusen Verfahren zur bestimmung von stoffwechselprodukten der arachidonsaeure mittels eines bindungsinhibitionstests an einem immunosorbent mit monoklonalen antikoerpern
US4559310A (en) * 1983-05-20 1985-12-17 Dana Farber Cancer Institute Assay methods and systems utilizing mast cell clones
JPS6111663A (ja) * 1984-06-28 1986-01-20 Ono Pharmaceut Co Ltd 酵素免疫測定法に用いられる酵素で標識されたロイコトリエン類
ES2060757T3 (es) * 1988-03-31 1994-12-01 Sankyo Co Metodo para la determinacion de derivados de acido araquidonico y equipo para el mismo.

Also Published As

Publication number Publication date
DE69217038D1 (de) 1997-03-06
CA2097417A1 (en) 1993-04-01
WO1993007493A1 (en) 1993-04-15
AU2652592A (en) 1993-05-03
DE69217038T2 (de) 1997-10-30
AU651249B2 (en) 1994-07-14
ATE148234T1 (de) 1997-02-15
EP0559871A1 (en) 1993-09-15
US5487977A (en) 1996-01-30
EP0559871B1 (en) 1997-01-22
JPH06503427A (ja) 1994-04-14

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