ES2097736T3 - Peptido ciclico con actividad antagonista de sustancia p y sustancia k. - Google Patents

Peptido ciclico con actividad antagonista de sustancia p y sustancia k.

Info

Publication number
ES2097736T3
ES2097736T3 ES89105225T ES89105225T ES2097736T3 ES 2097736 T3 ES2097736 T3 ES 2097736T3 ES 89105225 T ES89105225 T ES 89105225T ES 89105225 T ES89105225 T ES 89105225T ES 2097736 T3 ES2097736 T3 ES 2097736T3
Authority
ES
Spain
Prior art keywords
substance
cyclic peptide
antagonist activity
violaceoniger
steptomyces
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89105225T
Other languages
English (en)
Inventor
Tohru Kino
Motoaki Nishikawa
Masami Ezaki
Sumio Kiyoto
Masakuni Okuhara
Shigehiro Takase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2097736T3 publication Critical patent/ES2097736T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN COMPUESTO DE FORMULA DONDE LOS SIMBOLOS DEFINEN CIERTOS GRUPOS DE ATOMOS, PROCESOS PARA DU PREPARACION Y COMPUESTOS FARMACEUTICOS COMPRENDIENDOLOS COMO INGREDIENTE ACTIVO EN ASOCIACION CON UN PORTADOR O EXCIPIENTE SUBSTANCIALMENTE NO TOXICO FARMACEUTICAMENTE ACEPTABLE. EL INVENTO TAMBIEN COMPRENDE UN CULTIVO BIOLOGICAMENTE PURO DEL ORGANISMO STEPTOMYCES VIOLACEONIGER NO. 9326 (FREM BP - 1667).
ES89105225T 1988-04-05 1989-03-23 Peptido ciclico con actividad antagonista de sustancia p y sustancia k. Expired - Lifetime ES2097736T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888807921A GB8807921D0 (en) 1988-04-05 1988-04-05 Ws-9326 & its derivatives

Publications (1)

Publication Number Publication Date
ES2097736T3 true ES2097736T3 (es) 1997-04-16

Family

ID=10634574

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89105225T Expired - Lifetime ES2097736T3 (es) 1988-04-05 1989-03-23 Peptido ciclico con actividad antagonista de sustancia p y sustancia k.

Country Status (20)

Country Link
EP (1) EP0336230B1 (es)
JP (1) JP2551142B2 (es)
KR (1) KR0132567B1 (es)
CN (1) CN1037857C (es)
AT (1) ATE148890T1 (es)
AU (1) AU627453B2 (es)
CA (1) CA1335662C (es)
DE (1) DE68927759T2 (es)
DK (1) DK161789A (es)
ES (1) ES2097736T3 (es)
FI (1) FI102547B1 (es)
GB (1) GB8807921D0 (es)
GR (1) GR3023353T3 (es)
HU (1) HU204853B (es)
IL (1) IL89734A (es)
NO (1) NO177714C (es)
PH (1) PH30960A (es)
RU (2) RU1826970C (es)
UA (1) UA26845C2 (es)
ZA (1) ZA892188B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0360390A1 (en) * 1988-07-25 1990-03-28 Glaxo Group Limited Spirolactam derivatives
ZA903856B (en) * 1989-06-02 1991-05-29 Fujisawa Pharmaceutical Co Preparation of fri15224 substance for parenteral administration
FR2666335B1 (fr) 1990-09-05 1992-12-11 Sanofi Sa Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant.
EP0498069B1 (en) * 1990-12-21 1995-10-25 Fujisawa Pharmaceutical Co., Ltd. New use of peptide derivative
FR2688219B1 (fr) 1992-03-03 1994-07-08 Sanofi Elf Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
US5830854A (en) * 1992-12-14 1998-11-03 Merck Sharp & Dohme, Limited Method of treating cystic fibrosis using a tachykinin receptor antagonist
WO1994020126A1 (en) * 1993-03-03 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Use of peptides for the manufacture of a medicament
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2729954B1 (fr) 1995-01-30 1997-08-01 Sanofi Sa Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
US20100105688A1 (en) 2007-01-24 2010-04-29 Glaxo Group Limited Pharmaceutical compositions comprising 3,5-diamino-6-(2,3-dichlophenyl)-1,2,4-triazine or r(-)-2,4-diamino-5-(2,3-dichlorophenyl)-6-fluoromethyl pyrimidine and an nk1
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661473A (en) * 1984-03-27 1987-04-28 Merck & Co., Inc. Renin inhibitors containing peptide isosteres
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide
JPS6424156A (en) * 1987-07-17 1989-01-26 Yanmar Diesel Engine Co Air-fuel ratio control device for gas engine
JP2570670B2 (ja) * 1987-12-28 1997-01-08 味の素株式会社 トキソプラズマ増殖抑制剤
GB8802229D0 (en) * 1988-02-02 1988-03-02 Fujisawa Pharmaceutical Co Ws-9326 & its derivatives

Also Published As

Publication number Publication date
HU204853B (en) 1992-02-28
NO177714B (no) 1995-07-31
FI891581A0 (fi) 1989-04-03
HUT49631A (en) 1989-10-30
DE68927759T2 (de) 1997-06-19
CN1037857C (zh) 1998-03-25
RU2043365C1 (ru) 1995-09-10
RU1826970C (ru) 1993-07-07
FI102547B (fi) 1998-12-31
AU627453B2 (en) 1992-08-27
AU3239789A (en) 1989-10-12
ATE148890T1 (de) 1997-02-15
CN1036795A (zh) 1989-11-01
KR890016061A (ko) 1989-11-28
JPH02204499A (ja) 1990-08-14
KR0132567B1 (ko) 1998-04-14
FI102547B1 (fi) 1998-12-31
DK161789D0 (da) 1989-04-04
JP2551142B2 (ja) 1996-11-06
CA1335662C (en) 1995-05-23
UA26845C2 (uk) 1999-12-29
NO891389L (no) 1989-10-06
NO891389D0 (no) 1989-04-03
PH30960A (en) 1997-12-23
EP0336230A2 (en) 1989-10-11
EP0336230B1 (en) 1997-02-12
IL89734A (en) 1994-05-30
GR3023353T3 (en) 1997-08-29
ZA892188B (en) 1989-11-29
DE68927759D1 (de) 1997-03-27
IL89734A0 (en) 1989-09-28
DK161789A (da) 1989-10-06
FI891581A7 (fi) 1989-10-06
NO177714C (no) 1995-11-08
EP0336230A3 (en) 1991-07-17
GB8807921D0 (en) 1988-05-05

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